Zobrazeno 1 - 10 of 51 pro vyhledávání: '"Pei Ching Hsiao"'
1
Comparison of molecular responses and outcomes between BCR::ABL1 e14a2 and e13a2 transcripts in chronic myeloid leukemia
Autor: Yi‐Jiun Su, Ming‐Chung Kuo, Tsai‐Yun Chen, Ming‐Chung Wang, Youngsen Yang, Ming‐Chun Ma, Tung‐Liang Lin, Tung‐Huei Lin, Hung Chang, Chieh‐Lin Jerry Teng, Pei‐Ching Hsiao, Chih‐Cheng Chen, Po‐Nan Wang, Lee‐Yung Shih
Publikováno v: Cancer Science. 113:3518-3527
Several studies have compared the molecular responses between e14a2 and e13a2 BCR::ABL1 transcripts in chronic myeloid leukemia (CML) patients treated with front-line imatinib, but there were very limited studies on nilotinib or dasatinib-treated pat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e87e2150d5c2e47c09e48b4d21b131
https://doi.org/10.1111/cas.15501
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3
Akademický článek
Pterostilbene simultaneously induced G0/G1-phase arrest and MAPK-mediated mitochondrial-derived apoptosis in human acute myeloid leukemia cell lines.
Autor: Pei-Ching Hsiao, Ying-Erh Chou, Peng Tan, Wei-Jiunn Lee, Shun-Fa Yang, Jyh-Ming Chow, Hui-Yu Chen, Chien-Huang Lin, Liang-Ming Lee, Ming-Hsien Chien
Publikováno v: PLoS ONE, Vol 9, Iss 8, p e105342 (2014)
Pterostilbene (PTER) is a dimethylated analog of the phenolic phytoalexin, resveratrol, with higher anticancer activity in various tumors. Herein, the molecular mechanisms by which PTER exerts its anticancer effects against acute myeloid leukemia (AM
Externí odkaz: https://doaj.org/article/7e661e2bb30745d48113cb10667d87a0
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4
Akademický článek
Glabridin mediate caspases activation and induces apoptosis through JNK1/2 and p38 MAPK pathway in human promyelocytic leukemia cells.
Autor: Hsin-Lien Huang, Ming-Ju Hsieh, Ming-Hsien Chien, Hui-Yu Chen, Shun-Fa Yang, Pei-Ching Hsiao
Publikováno v: PLoS ONE, Vol 9, Iss 6, p e98943 (2014)
BACKGROUND: Glabridin, a prenylated isoflavonoid of G. glabra L. roots, has been associated with a wide range of biological properties such as regulation of energy metabolism, estrogenic, neuroprotective, anti-osteoporotic, and skin-whitening in prev
Externí odkaz: https://doaj.org/article/c2023514136f45f7a11b93a528628097
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5
Akademický článek
Licochalcone A suppresses migration and invasion of human hepatocellular carcinoma cells through downregulation of MKK4/JNK via NF-κB mediated urokinase plasminogen activator expression.
Autor: Jen-Pi Tsai, Pei-Ching Hsiao, Shun-Fa Yang, Shu-Ching Hsieh, Da-Tian Bau, Chu-Liang Ling, Chun-Li Pai, Yi-Hsien Hsieh
Publikováno v: PLoS ONE, Vol 9, Iss 1, p e86537 (2014)
Hepatocellular cell carcinoma (HCC) is one of the most commonly diagnosed cancers worldwide and in Taiwan. Chemoprevention of cancer with dietary bioactive compounds could potentially reverse, suppress, or prevent cancer progression. Licochalcone A (
Externí odkaz: https://doaj.org/article/daa9158162aa419d9bd28a7deec9978b
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6
Akademický článek
Effects of EZH2 polymorphisms on susceptibility to and pathological development of hepatocellular carcinoma.
Autor: Yung-Luen Yu, Kuo-Jung Su, Yi-Hsien Hsieh, Hsiang-Lin Lee, Tzy-Yen Chen, Pei-Ching Hsiao, Shun-Fa Yang
Publikováno v: PLoS ONE, Vol 8, Iss 9, p e74870 (2013)
The enhancer of zeste 2 (EZH2) gene encodes the histone methyltransferase that is the catalytic component of the polycomb repressive complex-2, which initiates epigenetic silencing of genes. The expression level of EZH2 in hepatocellular carcinoma (H
Externí odkaz: https://doaj.org/article/25b2647659d24618918569b87293b64a
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7
The Curcumin Analogue, EF-24, Triggers p38 MAPK-Mediated Apoptotic Cell Death via Inducing PP2A-Modulated ERK Deactivation in Human Acute Myeloid Leukemia Cells
Autor: Chia Chi Ku, Meng Ying Tsai, Shun-Fa Yang, Ming Hsien Chien, Jer Hwa Chang, Wei Jiunn Lee, Pei Ching Hsiao
Publikováno v: Cancers, Vol 12, Iss 2163, p 2163 (2020)
Cancers
Volume 12
Issue 8
Curcumin (CUR) has a range of therapeutic benefits against cancers, but its poor solubility and low bioavailability limit its clinical use. Demethoxycurcumin (DMC) and diphenyl difluoroketone (EF-24) are natural and synthetic curcumin analogues, resp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2679069c72c4cd78f7028ece38630b7b
https://www.mdpi.com/2072-6694/12/8/2163
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9
Cantharidic acid induces apoptosis of human leukemic HL-60 cells via c-Jun N-terminal kinase-regulated caspase-8/-9/-3 activation pathway
Autor: Pei Ching Hsiao, Shih Chung Wang, Ming Hsien Chien, Jyh Ming Chow, Shun-Fa Yang, Hui Yu Chen, Chiao Wen Lin
Publikováno v: Environmental toxicology. 33(4)
Cantharidin, a natural toxin from blister beetles, has shown potent anticancer activities on many solid tumor cells. Recently, cantharidin and its analogue, norcantharidin, were also shown to suppress nonsolid tumors such as chronic myeloid leukemia,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594732a149e442ab2c59d1aa6639949e
https://pubmed.ncbi.nlm.nih.gov/29345422
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10
Tricetin Induces Apoptosis of Human Leukemic HL-60 Cells through a Reactive Oxygen Species-Mediated c-Jun N-Terminal Kinase Activation Pathway
Autor: Pei Ching Hsiao, Hui Yu Chen, Ming Hsien Chien, Wei Jiunn Lee, Peng Tan, Yung Wei Lin, Jyh Ming Chow, Shun-Fa Yang, Yu Ching Wen
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 8, p 1667 (2017)
International Journal of Molecular Sciences; Volume 18; Issue 8; Pages: 1667
Tricetin is a dietary flavonoid with cytostatic properties and antimetastatic activities in various solid tumors. The anticancer effect of tricetin in nonsolid tumors remains unclear. Herein, the molecular mechanisms by which tricetin exerts its anti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::161ec515c3bda750b1c3b73071b56165
https://pubmed.ncbi.nlm.nih.gov/28758971
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