Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Pei Chi Yang"'
Autor:
Colleen E. Clancy, Pei Chi Yang, Jonathan D. Moreno, Xander H.T. Wehrens, Mao Tsuen Jeng, Sergei Y. Noskov
Publikováno v:
The Journal of Physiology. 594:6433-6435
The mechanism of therapeutic efficacy of flecainide for catecholaminergic polymorphic ventricular tachycardia (CPVT) is unclear. Model predictions suggest that Na(+) channel effects are insufficient to explain flecainide efficacy in CPVT. This study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f0efc686df348b6359ee6afcebc52a
https://doi.org/10.1113/jp273143
https://doi.org/10.1113/jp273143
Autor:
Gonzalo Hernandez-Hernandez, Samantha C O'Dwyer, Pei-Chi Yang, Collin Matsumoto, Mindy Tieu, Zhihui Fong, Timothy J Lewis, L Fernando Santana, Colleen E Clancy
Publikováno v:
eLife, Vol 12 (2024)
The function of the smooth muscle cells lining the walls of mammalian systemic arteries and arterioles is to regulate the diameter of the vessels to control blood flow and blood pressure. Here, we describe an in silico model, which we call the ‘Her
Externí odkaz:
https://doaj.org/article/e1c78cfe649246afb454472a4d6e05a3
Autor:
Yang PC; Department of Pharmacology, University of California, Davis, CA, USA., Moreno JD; Department of Medicine, Barnes-Jewish Hospital, Washington University in St Louis, St Louis, MO, USA., Jeng MT; Department of Pharmacology, University of California, Davis, CA, USA., Wehrens XH; Cardiovascular Research Institute, Department of Molecular Physiology & Biophysics, Department of Medicine, Cardiology, Baylor College of Medicine, Houston, TX, USA., Noskov S; Centre for Molecular Simulation, Department of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada., Clancy CE; Department of Pharmacology, University of California, Davis, CA, USA. ceclancy@ucdavis.edu.
Publikováno v:
The Journal of physiology [J Physiol] 2016 Nov 01; Vol. 594 (21), pp. 6433-6435.
Akademický článek
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Autor:
Hernandez-Hernandez, Gonzalo, O'Dwyer, Samantha C., Pei-Chi Yang, Matsumoto, Collin, Tieu, Mindy, Zhihui Fong, Lewis, Timothy J., Santana, L. Fernando, Clancy, Colleen E.
Publikováno v:
eLife; 2/9/2024, p1-30, 30p
Autor:
Parya Aghasafari, Pei-Chi Yang, Divya C Kernik, Kazuho Sakamoto, Yasunari Kanda, Junko Kurokawa, Igor Vorobyov, Colleen E Clancy
Publikováno v:
eLife, Vol 10 (2021)
The development of induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) has been a critical in vitro advance in the study of patient-specific physiology, pathophysiology, and pharmacology. We designed a new deep learning multitask network
Externí odkaz:
https://doaj.org/article/1cce6aa896514b5586df70ba8213b166
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 8, p e1008109 (2020)
In the last decade, there has been tremendous progress in identifying genetic anomalies linked to clinical disease. New experimental platforms have connected genetic variants to mechanisms underlying disruption of cellular and organ behavior and the
Externí odkaz:
https://doaj.org/article/cd9eeae8737b439684cd9e37115ffe67
Autor:
Pei-Chi Yang, M. Saleet Jafri
Publikováno v:
Heliyon, Vol 6, Iss 3, Pp e03526- (2020)
T cell receptor stimulation initiates a cascade of reactions that cause an increase in intracellular calcium (Ca2+) concentration mediated through inositol 1,4,5-trisphosphate (IP3). To understand the basic mechanisms by which the immune response in
Externí odkaz:
https://doaj.org/article/55549d88cb7a48499a1923895f4907f3
Autor:
Tian-Hoe Tan, Ting-Ya Yang, Yao-Mei Chen, Shiu-Yuan Chung, Hsiao-Hua Liu, Pei-Chi Yang, Pei-Hsin Kao, An-Chi Peng, Yi-Min Shu, Yu-Sheng Chu, Kang-Ting Tsai, Chien-Chin Hsu, Chung-Han Ho, Hung-Jung Lin, Chien-Cheng Huang
Publikováno v:
Aging Clinical and Experimental Research. 34:3137-3144
A computerized tool and interdisciplinary care were implemented to develop a novel model for older patients with delirium in the emergency department (ED).We developed a computerized tool using a delirium triage screen and brief confusion assessment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1590ba1a449655a495b11b256db82349
https://doi.org/10.1007/s40520-022-02240-7
https://doi.org/10.1007/s40520-022-02240-7
Autor:
Pei-Chi Yang, Shweta Purawat, Pek U Ieong, Mao-Tsuen Jeng, Kevin R DeMarco, Igor Vorobyov, Andrew D McCulloch, Ilkay Altintas, Rommie E Amaro, Colleen E Clancy
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 3, p e1006856 (2019)
Multi-scale computational modeling is a major branch of computational biology as evidenced by the US federal interagency Multi-Scale Modeling Consortium and major international projects. It invariably involves specific and detailed sequences of data
Externí odkaz:
https://doaj.org/article/a9798631d43e4238936e418a85225114