Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Pei‐Hsuan Chen"'
Autor:
Deepti Gadi, Stephen P. Martindale, Pui Yan Chiu, Jasneet Khalsa, Pei-Hsuan Chen, Stacey M. Fernandes, Zixu Wang, Svitlana Tyekucheva, John-Hanson Machado, David C. Fisher, Philippe Armand, Matthew S. Davids, Scott Rodig, Barbara Sherry, Jennifer R. Brown
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract PI3Kδ inhibitors are approved for the therapy of B cell malignancies, but their clinical use has been limited by unpredictable autoimmune toxicity, despite promising efficacy and evidence that toxicity is associated with improved clinical o
Externí odkaz:
https://doaj.org/article/94914f0b3bca45c9ad51c3edd14b1ac9
Publikováno v:
Journal of Functional Foods, Vol 108, Iss , Pp 105759- (2023)
Alcohol consumption causes alcoholic liver diseases (ALD). The aim of this study investigated whether the mechanisms of the effects of dehulled adlay on ALD by using a chronic ethanol feeding plus single binge model. Rats were pair-fed with a control
Externí odkaz:
https://doaj.org/article/9df5dfefd3cf4cfbb0e39ff0a7e346eb
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Background Adipose tissue inflammation is considered as one of the major mechanisms underlying the pathogenesis of insulin resistance and complications in diabetes. Here, we aimed to study the effects of adipose-derived stromal cells on diab
Externí odkaz:
https://doaj.org/article/d1ab092c0e224d16929cc3c5324f9b92
Autor:
Ning Wang, Aoni Xu, Pengfei Ou, Sung-Fu Hung, Adnan Ozden, Ying-Rui Lu, Jehad Abed, Ziyun Wang, Yu Yan, Meng-Jia Sun, Yujian Xia, Mei Han, Jingrui Han, Kaili Yao, Feng-Yi Wu, Pei-Hsuan Chen, Alberto Vomiero, Ali Seifitokaldani, Xuhui Sun, David Sinton, Yongchang Liu, Edward H. Sargent, Hongyan Liang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Metal borides/borates are promising candidates to become high-performance alkaline oxygen evolution reaction catalysts. This study reports an in-situ phase composition modulation approach to fabricate boride/borate-based catalysts.
Externí odkaz:
https://doaj.org/article/357654ab658b43b8a6a6077c410fcab6
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-19 (2020)
Abstract Nonalcoholic fatty liver disease (NAFLD) is a common metabolic syndrome. Imbalances between liver lipid output and input are the direct causes of NAFLD, and hepatic steatosis is the pathological premise and basis for NAFLD progression. Mutua
Externí odkaz:
https://doaj.org/article/43f043efc4ca487090736d8fa8260a95
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract Background Infection by antibiotic-resistant microorganisms is common in intensive care units and has become a global problem. Here, we determined the effect of aryl hydrocarbon receptor (AhR) stimulation on antibiotics-induced systemic defe
Externí odkaz:
https://doaj.org/article/386eddf364c2445fa7d931a934e245b5
Autor:
Szu-Yu Chen, Chi-Fu Chiang, Kou-Chou Chiu, Chao-Wen Cheng, Shih-Ming Huang, Pei-Hsuan Chen, Ching-Yang Chen, Yi-Shing Shieh
Publikováno v:
Journal of Dental Sciences, Vol 14, Iss 3, Pp 281-287 (2019)
Background/purpose: Macrophages participate in the periapical inflammation with pro-inflammatory M1 cells and anti-inflammatory M2 cells. Gas6/Axl signal is the responsible pathway for the activation of M1 and polarization of M2. The aim of this stud
Externí odkaz:
https://doaj.org/article/10930b7d5dfc4b9bb9e6cca80bc49754
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0252153 (2021)
Adipose tissue inflammation is a major cause of the pathogenesis of obesity and comorbidities. To study the involvement of M1/M2 cytokine expression of adipose tissue in the regulatory mechanisms of dipeptidyl peptidase 4 (DPP4) and insulin resistanc
Externí odkaz:
https://doaj.org/article/25bf716a7a434aab8d7f0410e617444e
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-15 (2018)
Abstract Background Widespread use of antibiotics in the intensive care unit is a potential cause of the emergence of hospital-acquired pneumonia. This study determined whether Lactobacillus salivarius feeding could reverse antibiotic-induced lung de
Externí odkaz:
https://doaj.org/article/6d0cdada962645d38d1294a6a75cec16
Autor:
Barrett L. Updegraff, Xiaorong Zhou, Yabin Guo, Mahesh S. Padanad, Pei-Hsuan Chen, Chendong Yang, Jessica Sudderth, Carla Rodriguez-Tirado, Luc Girard, John D. Minna, Prashant Mishra, Ralph J. DeBerardinis, Kathryn A. O’Donnell
Publikováno v:
Cell Reports, Vol 25, Iss 8, Pp 2223-2233.e6 (2018)
Summary: Pathways underlying metabolic reprogramming in cancer remain incompletely understood. We identify the transmembrane serine protease TMPRSS11B as a gene that promotes transformation of immortalized human bronchial epithelial cells (HBECs). TM
Externí odkaz:
https://doaj.org/article/8830c3d646e74fa1ad38b656919ff687