Deciphering the impact of STAT3 activation mediated by PTPRT promoter hypermethylation as biomarker of response to paclitaxel-plus-cetuximab in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.

Autor: Cirauqui BC; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Head and Neck Functional Unit, Catalan Institute of Oncology (ICO), Badalona, Spain., Peguera AB; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Pi-Sunyer AQ; Head and Neck Functional Unit, Catalan Institute of Oncology (ICO), Badalona, Spain.; Department of Pathology, Germans Trias i Pujol Hospital, Badalona, Spain., Ferrando-Díez A; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Head and Neck Functional Unit, Catalan Institute of Oncology (ICO), Badalona, Spain., Serrano JLR; Molecular Biology Unit, Hematology Laboratory, Catalan Institute of Oncology (ICO), Badalona, Spain., Viñolas MD; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., García IT; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., García VQ; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Oukadour IC; Laboratory of Cellular and Molecular Biology, Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Valencia AG; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Vergara PH; Head and Neck Functional Unit, Catalan Institute of Oncology (ICO), Badalona, Spain., de Aguirre Egaña I; Molecular Biology Unit, Hematology Laboratory, Catalan Institute of Oncology (ICO), Badalona, Spain., Herrero CQ; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Resistance Cancer Predictive Biomarkers Group, ProCURE Program-Catalan Institute of Oncology, Badalona, Spain., Carbonell OM; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Paradís AL; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Esteve A; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Vila MM; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Rosell R; Laboratory of Cellular and Molecular Biology, Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Martínez-Cardús A; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Mesía R; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Spain.; Badalona Applied Research Group in Oncology (BARGO), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.; Translational Program in Cancer Research (CARE), Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.

Publikováno v: Head & neck [Head Neck] 2025 Jan; Vol. 47 (1), pp. 57-67. Date of Electronic Publication: 2024 Jul 27.