Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Pegine B, Walrad"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
A large number of eukaryotic proteins are processed by single or combinatorial post-translational covalent modifications that may alter their activity, interactions and fate. The set of modifications of each protein may be considered a “regulatory
Externí odkaz:
https://doaj.org/article/d1c7e9d7814f425eb95a8ecb670e8cd1
Autor:
Rachel C Findlay, Mohamed Osman, Kirstin A Spence, Paul M Kaye, Pegine B Walrad, Laurence G Wilson
Publikováno v:
eLife, Vol 10 (2021)
Cellular motility is an ancient eukaryotic trait, ubiquitous across phyla with roles in predator avoidance, resource access, and competition. Flagellar motility is seen in various parasitic protozoans, and morphological changes in flagella during the
Externí odkaz:
https://doaj.org/article/228f928220244c1e99f120c6214cb864
Autor:
Juliana Alcoforado Diniz, Mariana M Chaves, Slavica Vaselek, Rubens D Miserani Magalhães, Rafael Ricci-Azevedo, Renan V H de Carvalho, Lucas B Lorenzon, Tiago R Ferreira, Dario Zamboni, Pegine B Walrad, Petr Volf, David L Sacks, Angela K Cruz
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0009230 (2021)
Leishmania major is the main causative agent of cutaneous leishmaniasis in the Old World. In Leishmania parasites, the lack of transcriptional control is mostly compensated by post-transcriptional mechanisms. Methylation of arginine is a conserved po
Externí odkaz:
https://doaj.org/article/fc6c456a480446dd8f8cc9b8f8b6c3d8
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0009033 (2021)
Leishmaniasis is a neglected tropical disease which kills an estimated 50,000 people each year, with its deadly impact confined mainly to lower to middle income countries. Leishmania parasites are transmitted to human hosts by sand fly vectors during
Externí odkaz:
https://doaj.org/article/a301ed86cd2347ab8ae332d9fdb2e2f0
Autor:
Tony Isebe, Suellen Rodrigues Maran, Pegine B. Walrad, Igor Cestari, Nilmar Silvio Moretti, Krista Fleck, Elton J R Vasconcelos, Victoria Jeffers, Natália Melquie Monteiro-Teles
Publikováno v:
Trends Parasitol
Protein lysine acetylation has emerged as a major regulatory post-translational modification in different organisms, present not only on histone proteins affecting chromatin structure and gene expression but also on nonhistone proteins involved in se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de18e6b85b1e5962f0248e6a8ddca2c
https://doi.org/10.1016/j.pt.2021.04.008
https://doi.org/10.1016/j.pt.2021.04.008
Autor:
Vijani Somaratne, Mitali Chatterjee, Marcela Montes de Oca, Pegine B. Walrad, Dimitris Lagos, Nidhi S. Dey, Renu Wickremasinghe, Srija Moulik, Bimalka Seneviratne, Hiro Goto, Sujai Senarathna, Paul M. Kaye, Shalindra Ranasinghe, Nayani Madarasinghe, Luiza Campos Reis, Sarah Forrester
Publikováno v:
The Journal of Clinical Investigation
Cutaneous leishmaniasis (CL) is a chronic skin disease caused by Leishmania parasites and in Sri Lanka, CL is caused by L. donovani. Pentavalent antimonials (e.g. sodium stibogluconate; SSG) are first line drugs for CL, despite protracted and painful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db580da50412b23fac6ee64fe76bb0c9
http://europepmc.org/articles/PMC8592550
http://europepmc.org/articles/PMC8592550
Autor:
Laurence G. Wilson, Kirstin A Spence, Rachel C Findlay, Pegine B. Walrad, Mohamed Osman, Paul M. Kaye
Publikováno v:
eLife, Vol 10 (2021)
Cellular motility is an ancient eukaryotic trait, ubiquitous across phyla with roles in predator avoidance, resource access, and competition. Flagellar motility is seen in various parasitic protozoans, and morphological changes in flagella during the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aba31ac9e39f4e888248992f462d1ad
https://eprints.whiterose.ac.uk/175718/1/elife_65051_v1.pdf
https://eprints.whiterose.ac.uk/175718/1/elife_65051_v1.pdf
Publikováno v:
Parasitology
Trypanothione is the primary thiol redox carrier in Trypanosomatids whose biosynthesis and utilization pathways contain unique enzymes that include suitable drug targets against the human parasites in this family. Overexpression of the rate-limiting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cff3e164839f50723af92816be75031
https://pubmed.ncbi.nlm.nih.gov/33602349
https://pubmed.ncbi.nlm.nih.gov/33602349
Autor:
Rafael Ricci-Azevedo, Mariana M. Chaves, Dario S. Zamboni, Rubens Daniel Miserani Magalhães, Tiago R. Ferreira, Pegine B. Walrad, Renan V. H. de Carvalho, David L. Sacks, Slavica Vaselek, Angela K. Cruz, Juliana Alcoforado Diniz, Lucas B. Lorenzon, Petr Volf
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0009230 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS Neglected Tropical Diseases
PLOS Neglected Tropical Diseases
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS Neglected Tropical Diseases
PLOS Neglected Tropical Diseases
Leishmania major is the main causative agent of cutaneous leishmaniasis in the Old World. In Leishmania parasites, the lack of transcriptional control is mostly compensated by post-transcriptional mechanisms. Methylation of arginine is a conserved po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19cb51e29b2c50b89620c84d3976760
https://doaj.org/article/fc6c456a480446dd8f8cc9b8f8b6c3d8
https://doaj.org/article/fc6c456a480446dd8f8cc9b8f8b6c3d8