Zobrazeno 1 - 10
of 557
pro vyhledávání: '"Peghaire, A."'
Publikováno v:
In Journal of Thrombosis and Haemostasis November 2023 21(11):3056-3066
Autor:
C. Peghaire, N. P. Dufton, M. Lang, I. I. Salles-Crawley, J. Ahnström, V. Kalna, C. Raimondi, C. Pericleous, L. Inuabasi, R. Kiseleva, V. R. Muzykantov, J. C. Mason, G. M. Birdsey, A. M. Randi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
The endothelium actively maintains an anticoagulant surface through expression of thrombomodulin. Here, Peghaire et al. identify an anti-thrombotic pathway that controls thrombomodulin expression selectively in regions of low shear stress, via cooper
Externí odkaz:
https://doaj.org/article/7798914f5f094e87a7d8b776f5a7230c
Autor:
Kilani, Badr, Gourdou‐Latyszenok, Virginie, Guy, Alexandre, Bats, Marie‐Lise, Peghaire, Claire, Parrens, Marie, Renault, Marie‐Ange, Duplàa, Cecile, Villeval, Jean‐Luc, Rautou, Pierre‐Emmanuel, Couffinhal, Thierry, James, Chloe *
Publikováno v:
In Journal of Thrombosis and Haemostasis May 2019 17(5):827-840
Autor:
Jesus M. Gomez-Salinero, Tomer Itkin, Sean Houghton, Chaitanya Badwe, Yang Lin, Viktoria Kalna, Neil Dufton, Claire R. Peghaire, Masataka Yokoyama, Matthew Wingo, Tyler M. Lu, Ge Li, Jenny Zhaoying Xiang, Yen-Michael Sheng Hsu, David Redmond, Ryan Schreiner, Graeme M. Birdsey, Anna M. Randi, Shahin Rafii
Publikováno v:
Nat Cardiovasc Res
Current dogma dictates that, during adulthood, endothelial cells (ECs) are locked in an immutable stable homeostatic state. By contrast, herein we show that maintenance of EC fate and function are linked and active processes, which depend on the cons
Autor:
Neil P. Dufton, Claire R. Peghaire, Lourdes Osuna-Almagro, Claudio Raimondi, Viktoria Kalna, Abhishek Chauhan, Gwilym Webb, Youwen Yang, Graeme M. Birdsey, Patricia Lalor, Justin C. Mason, David H. Adams, Anna M. Randi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The transcription factor ERG is key to endothelial lineage specification and vascular homeostasis. Here the authors show that ERG balances TGFβ signalling through the SMAD1 and SMAD3 pathways, protecting the endothelium from endothelial-to-mesenchym
Externí odkaz:
https://doaj.org/article/688d3e51bd6e4384bf9ccbf1181bb7d6
Autor:
A. V. Shah, G. M. Birdsey, C. Peghaire, M. E. Pitulescu, N. P. Dufton, Y. Yang, I. Weinberg, L. Osuna Almagro, L. Payne, J. C. Mason, H. Gerhardt, R. H. Adams, A. M. Randi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Vascular maturation and stability is regulated by Notch and Angiopoietin-1/Tie2 signalling. Here, Shahet al. show that the transcription factor ERG coordinates the Ang1, Notch and Wnt/β-catenin pathways to promote vascular maturation and stability.
Externí odkaz:
https://doaj.org/article/5f4b6819b7ab45719c0100c6dc529987
Autor:
Alexandre Guy, Virginie Gourdou-Latyszenok, Nicolas Le Lay, Claire Peghaire, Badr Kilani, Juliana Vieira Dias, Cécile Duplaa, Marie-Ange Renault, Cécile Denis, Jean Luc Villeval, Yacine Boulaftali, Martine Jandrot-Perrus, Thierry Couffinhal, Chloe James
Publikováno v:
Haematologica, Vol 104, Iss 1 (2019)
Thrombosis is the main cause of morbidity and mortality in patients with JAK2V617F myeloproliferative neoplasms. Recent studies have reported the presence of JAK2V617F in endothelial cells of some patients with myeloproliferative neoplasms. We invest
Externí odkaz:
https://doaj.org/article/2fa70e2d604a4b19b50aa6fedb21a695
Autor:
Elodie Peghaire, Samar Hamdache, Antonin Galien, Mohamad Sleiman, Alexandra ter Halle, Hicham El Alaoui, Ayhan Kocer, Claire Richard, Pascale Goupil
Publikováno v:
Forests, Vol 11, Iss 6, p 705 (2020)
Red maple leaf extracts (RME) were tested for their plant defense inducer (PDI) properties. Two extracts were obtained and compared by different approaches: RME1 using ethanol–water (30–70%, v/v, 0.5% HCl 1N) and RME2 using pure water. Both extra
Externí odkaz:
https://doaj.org/article/be661edb864f4f1f92c2e8ff066e51cf
Autor:
Neil P. Dufton, Claire R. Peghaire, Lourdes Osuna-Almagro, Claudio Raimondi, Viktoria Kalna, Abhishek Chauhan, Gwilym Webb, Youwen Yang, Graeme M. Birdsey, Patricia Lalor, Justin C. Mason, David H. Adams, Anna M. Randi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/09a0a6c4e2f844d885132da763c799de
Autor:
McCracken, I, Saginc, G, He, L, Huseynov, A, Daniels, A, Fletcher, S, Peghaire, C, Kalna, V, Andaloussi-Mäe, M, Muhl, L, Craig, NM, Griffiths, SJ, Haas, JG, Tait-Burkard, C, Lendahl, U, Birdsey, GM, Betsholtz, C, Noseda, M, Baker, A, Randi, AM
A striking feature of severe COVID-19 is thrombosis in large as well as small vessels of multiple organs. This has led to the assumption that SARS-CoV-2 virus directly infects and damages the vascular endothelium. However, endothelial expression of A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::59647085ce07a2b153c16ee598b05d42
http://hdl.handle.net/10044/1/98346
http://hdl.handle.net/10044/1/98346