Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Peggy Wentworth"'
Autor:
Inge van der Werf, Phoebe K. Mondala, S. Kathleen Steel, Larisa Balaian, Luisa Ladel, Cayla N. Mason, Raymond H. Diep, Jessica Pham, Jacqueline Cloos, Gertjan J.L. Kaspers, Warren C. Chan, Adam Mark, James J. La Clair, Peggy Wentworth, Kathleen M. Fisch, Leslie A. Crews, Thomas C. Whisenant, Michael D. Burkart, Mary E. Donohoe, Catriona H.M. Jamieson
Publikováno v:
Cell reports. Medicine, vol 4, iss 3
Cell reports. Medicine, 4(3):100962. Cell Press
Cell Reports Medicine, 4(3):100962. Cell Press
van der Werf, I, Mondala, P K, Steel, S K, Balaian, L, Ladel, L, Mason, C N, Diep, R H, Pham, J, Cloos, J, Kaspers, G J L, Chan, W C, Mark, A, la Clair, J J, Wentworth, P, Fisch, K M, Crews, L A, Whisenant, T C, Burkart, M D, Donohoe, M E & Jamieson, C H M 2023, ' Detection and targeting of splicing deregulation in pediatric acute myeloid leukemia stem cells ', Cell reports. Medicine, vol. 4, no. 3, 100962, pp. 100962 . https://doi.org/10.1016/j.xcrm.2023.100962, https://doi.org/10.1016/j.xcrm.2023.100962
Cell reports. Medicine, 4(3):100962. Cell Press
Cell Reports Medicine, 4(3):100962. Cell Press
van der Werf, I, Mondala, P K, Steel, S K, Balaian, L, Ladel, L, Mason, C N, Diep, R H, Pham, J, Cloos, J, Kaspers, G J L, Chan, W C, Mark, A, la Clair, J J, Wentworth, P, Fisch, K M, Crews, L A, Whisenant, T C, Burkart, M D, Donohoe, M E & Jamieson, C H M 2023, ' Detection and targeting of splicing deregulation in pediatric acute myeloid leukemia stem cells ', Cell reports. Medicine, vol. 4, no. 3, 100962, pp. 100962 . https://doi.org/10.1016/j.xcrm.2023.100962, https://doi.org/10.1016/j.xcrm.2023.100962
Pediatric acute myeloid leukemia (pAML) is typified by high relapse rates and a relative paucity of somatic DNA mutations. Although seminal studies show that splicing factor mutations and mis-splicing fuel therapy-resistant leukemia stem cell (LSC) g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635fc2f87ba6c7bb45c6b2245e0c70ae
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85150286973&origin=inward
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85150286973&origin=inward
Autor:
Leslie A. Crews, Wenxue Ma, Luisa Ladel, Jessica Pham, Larisa Balaian, S. Kathleen Steel, Phoebe K. Mondala, Raymond H. Diep, Christina N. Wu, Cayla N. Mason, Inge van der Werf, Isabelle Oliver, Eduardo Reynoso, Gabriel Pineda, Thomas C. Whisenant, Peggy Wentworth, James J. La Clair, Qingfei Jiang, Michael D. Burkart, Catriona H.M. Jamieson
Publikováno v:
Cell Stem Cell. 30:250-263.e6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::479f480adc67d87af29db08fbda10b67
https://doi.org/10.1016/j.stem.2023.01.008
https://doi.org/10.1016/j.stem.2023.01.008
Autor:
Inge Van Der Werf, Kathleen Steel, Phoebe Mondala, Larissa Balaian, Jacqueline Cloos, Gertjan J.L. Kaspers, James La Clair, Peggy Wentworth, Kathleen Fisch, Leslie Crews, Thomas Whisenant, Michael Burkart, Mary Donohoe, Catriona Jamieson
Publikováno v:
Blood. 140:3354-3355
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0642da34db5d821bfd620c5b49d4d3fe
https://doi.org/10.1182/blood-2022-171145
https://doi.org/10.1182/blood-2022-171145
Autor:
Cayla Mason, Phoebe Mondala, Inge van der Werf, Ruben van Boxtel, Markus J van Roosmalen, Kathleen M. Fisch, Jacqueline Cloos, Adam Mark, Raymond Diep, Larisa Balaian, James J. La Clair, Leslie Crews, Gertjan J.L. Kaspers, Luisa Ladel, Catriona Jamieson, Warren C. W. Chan, Kathleen Steel, Thomas Whisenant, Peggy Wentworth, Mary Donohoe, Michael D. Burkart
Publikováno v:
Mondala, P, Van Der Werf, I, Balaian, L, Steel, K, Ladel, L, Mason, C, Diep, R, Cloos, J, Kaspers, G, van Roosmalen, M J, Van Boxtel, R, Chan, W, Mark, A, Donohoe, M, La Clair, J, Wentworth, P, Fisch, K, Crews, L A, Whisenant, T, Burkart, M & Jamieson, C 2021, ' Deregulation of Splicing in Pediatric Acute Myeloid Stem and Progenitor Cells ', Blood, vol. 138 . https://doi.org/10.1182/blood-2021-154120
Blood, 138. American Society of Hematology
Blood, 138. American Society of Hematology
Currently, the limited capacity of pediatric acute myeloid leukemia (AML) therapies to prevent recurrence has contributed to high mortality rates. While dormant self-renewing leukemia stem cells (LSCs) contribute to adult AML relapse, their role in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d410fc7237fa86fcd9dbbeb5e49ba660
https://doi.org/10.1182/blood-2021-154120
https://doi.org/10.1182/blood-2021-154120
Autor:
Peggy Wentworth, Catriona Jamieson, Cayla Mason, Christina C.N. Wu, Phoebe Mondala, Larisa Balaian, Wenxue Ma, Michael D. Burkart, Jessica Pham, James J. La Clair, Leslie Crews
Publikováno v:
Blood. 138:3321-3321
Secondary acute myeloid leukemia (sAML) is the most therapeutically recalcitrant form of AML with a life expectancy of less than 12 months. Secondary AML evolves from relatively prevalent myeloproliferative neoplasms (MPNs), myelodysplastic syndrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cb355cfebb2d247c7c481c511db9fb2
https://doi.org/10.1182/blood-2021-154233
https://doi.org/10.1182/blood-2021-154233
Autor:
Larissa Balaian, Inge van der Werf, Jacqueline Cloos, Peggy Wentworth, Gertjan J.L. Kaspers, Leslie Crews, Kathleen M. Fisch, Thomas Whisenant, Cayla Mason, Phoebe Mondala, Michael D. Burkart, Raymond Diep, Catriona Jamieson, Jim La Clair
Publikováno v:
Blood. 136:8-8
INTRODUCTION Because acute myeloid leukemia (AML) is the leading cause of pediatric leukemia relapse-related mortality, there is a desperate need for developing new therapeutics and providing mechanistic insights into the cell type and molecular cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::079813cb98df63ae365f57239ff3baff
https://doi.org/10.1182/blood-2020-136596
https://doi.org/10.1182/blood-2020-136596
Autor:
Catriona Jamieson, Peggy Wentworth, Jim La Clair, Jacqueline Cloos, Gertjan J.L. Kaspers, Katie Fisch, Larisa Balaian, Tom Whisenant, Inge van der Werf, Michael D. Burkart, Cayla Mason, Phoebe Mondala, Raymond Diep
Publikováno v:
Cancer Research. 80:469-469
While 5 year survival rates for acute lymphoblastic leukemia (ALL) in childhood are 90% (https://www.cancer.org/cancer/leukemia-in-children/detection-diagnosis-staging/survival-rates.html), acute myeloid leukemia survival rates have lagged behind at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e845c8328f4392990f573d78f576a39
https://doi.org/10.1158/1538-7445.am2020-469
https://doi.org/10.1158/1538-7445.am2020-469
Autor:
Catriona Jamieson, Maurizio Pellecchia, Wenxue Ma, Lawrence S.B. Goldstein, Alice Y. Shih, Maryla Krajewska, Kelly A. Frazer, Janine M. Low-Marchelli, Anil Sadarangani, John C. Reed, Karen Messer, Ifat Geron, Minya Pu, Christian L. Barrett, Dayong Zhai, Sheldon R. Morris, Lei Bao, Daniel Goff, Hye Jung E. Chun, Jessica M. Rusert, Thomas J. Hudson, Angela Court Recart, Kim Hien T. Dao, Peggy Wentworth, Mark D. Minden, Ryan Chuang, Christina Jamieson, Jason Gotlib, Kristen M. Smith, Jun Wei, Kamran Shazand, Giovanni Martinelli, Heather Leu, Marco A. Marra, Larisa Balaian
Publikováno v:
Cell Stem Cell. 12(3):316-328
SummaryLeukemia stem cells (LSCs) play a pivotal role in the resistance of chronic myeloid leukemia (CML) to tyrosine kinase inhibitors (TKIs) and its progression to blast crisis (BC), in part, through the alternative splicing of self-renewal and sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcec4d248dc5222d4c3b8491f2ea003d
Autor:
Robert W. Chesnut, Philip J. R. Goulder, Spyros A. Kalams, Christian Brander, John Fikes, Bruce D. Walker, Mark J. Newman, Marcus Altfeld, Susan Buchbinder, Peggy Wentworth, Robert L. Eldridge, Alessandro Sette, Eric S. Rosenberg, Marylyn M. Addo, Amy K. Shea, Brian D. Livingston, Paul E. Sax, Steve Boswell, Neha Reshamwala, John Sidney, Phuong Thi Nguyen, Theresa Flynn, Gregory K. Robbins
Virus-specific cytotoxic T-lymphocyte (CTL) responses are critical in the control of human immunodeficiency virus type 1 (HIV-1) infection and will play an important part in therapeutic and prophylactic HIV-1 vaccines. The identification of virus-spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36d59dbb958b5f98b277ba3df1c746c
https://doi.org/10.1128/jvi.75.3.1301-1311.2001
https://doi.org/10.1128/jvi.75.3.1301-1311.2001
Autor:
Ajesh Maewal, Alessandro Sette, Howard M. Grey, Carla Oseroff, Jeff Alexander, John Fikes, Carol Dahlberg, Robert W. Chesnut, Peggy Wentworth, Esteban Celis, Ralph T. Kubo
Publikováno v:
Vaccine. 16:823-833
Various peptide-based approaches to simultaneous induction of multiple cytotoxic T lymphocyte (CTL) responses were evaluated as part of ongoing efforts to develop immunotherapeutic vaccines for use in humans. To this end, HLA (human histocompatibilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298a6223a52ff06b1ed651c6b00036b8
https://doi.org/10.1016/s0264-410x(97)00264-8
https://doi.org/10.1016/s0264-410x(97)00264-8