Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Peggy Tom"'
Autor:
Susan Peng, Nancy M. Dahms, Ravi Kambampati, Xu Wang, Jonathan H. LeBowitz, Peggy Tom, John Maga, Richard N. Bohnsack, Jianghong Zhou, Angela M. Thomm, Barry J. Byrne, Sarah Golata
Publikováno v:
The Journal of Biological Chemistry
Background: Acid α-glucosidase, an enzyme replacement therapy for Pompe disease, is poorly targeted to lysosomes when relying on phosphomannose residues. Results: Fusing IGF-II to acid α-glucosidase resulted in more efficient uptake and glycogen cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d0e09aeec5bd4ae887d48d36e2e357
https://doi.org/10.1074/jbc.m112.438663
https://doi.org/10.1074/jbc.m112.438663
Autor:
Jenni Firrman, LinShu Liu, Karley Mahalak, Weiming Hu, Kyle Bittinger, Ahmed Moustafa, Steven M. Jones, Adrienne Narrowe, Peggy Tomasula
Publikováno v:
Frontiers in Nutrition, Vol 9 (2023)
IntroductionFollowing consumption of milk, lactose, a disaccharide of glucose and galactose, is hydrolyzed and absorbed in the upper gastrointestinal tract. However, hydrolysis and absorption are not always absolute, and some lactose will enter the c
Externí odkaz:
https://doaj.org/article/3036441a7bab48bc9cc3edb91c6cb096
Publikováno v:
Antiviral Research. 38:107-116
Herpes simplex virus-type 1 (HSV-1) encodes both the small (UL40) and large (UL39) subunits of the enzyme, ribonucleotide reductase. Treatment of HSV-1-infected cells with interferon-alpha (IFN-alpha) reduced the levels of both enzyme subunits. Reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079008726db50e03bc04af1c521a65f5
https://doi.org/10.1016/s0166-3542(98)00016-3
https://doi.org/10.1016/s0166-3542(98)00016-3
Publikováno v:
Journal of Interferon & Cytokine Research. 16:937-940
ISG-15, a 15-kDa protein encoded by an interferon (IFN)-stimulated gene (ISG), was produced in human corneal cell cultures prepared from donor corneas in response to each of three major types of IFN, IFN-alpha, IFN-beta, and IFN-gamma. IFN-alpha and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c002c052d211e592b72b2b469a7f3d
https://doi.org/10.1089/jir.1996.16.937
https://doi.org/10.1089/jir.1996.16.937
Publikováno v:
Antiviral research. 38(2)
Treatment of cells with combinations of human interferon-alpha (IFN-alpha) and the nucleoside analog, acyclovir (ACV), leads to the synergistic inhibition of herpes simplex virus type 1 (HSV-1) replication. We have examined the effect of these agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700ea8ec120b3025349dc6af3efa4a79
https://pubmed.ncbi.nlm.nih.gov/9707372
https://pubmed.ncbi.nlm.nih.gov/9707372
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 15(1)
The 2',5'-oligoadenylate (2-5A) synthetase pathway, induced by interferon-alpha (IFN-alpha), has been shown to be responsible for the antiviral action of IFN-alpha against some viruses. Studies were done to determine the role of this pathway in the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fadbf1047d4d848f33dbfe6683b53da1
https://pubmed.ncbi.nlm.nih.gov/7648430
https://pubmed.ncbi.nlm.nih.gov/7648430
Alpha interferon (IFN-alpha) and acyclovir (ACV) are synergistic in their anti-herpes simplex virus activities. IFN-alpha treatment reduced the herpes simplex virus thymidine kinase (TK) activity present in cells 6 h postinfection, while steady-state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0093bb7e70769d93072cedb524b8bd0
https://europepmc.org/articles/PMC284554/
https://europepmc.org/articles/PMC284554/
Autor:
Minqian Wang, Jenni Firrman, Liqing Zhang, Gustavo Arango-Argoty, Peggy Tomasula, LinShu Liu, Weidong Xiao, Kit Yam
Publikováno v:
Molecules, Vol 22, Iss 8, p 1292 (2017)
Apigenin is a major dietary flavonoid with many bioactivities, widely distributed in plants. Apigenin reaches the colon region intact and interacts there with the human gut microbiota, however there is little research on how apigenin affects the gut
Externí odkaz:
https://doaj.org/article/ef91b30dedbc4ba2b017fad98ff8a6a4