Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Peggy S. Zelenka"'
Autor:
Brenna K. Harrington, Senthil S. Saravanamuthu, Lijin Dong, Pushpa Pandiyan, Natarajan Bhaskaran, Lixin Zheng, Carol J. Thiele, Chunhua Yan, Ying Hu, Peggy S. Zelenka, Vassili Bletsos, Zhihui Liu, Fengchun Ye, Rachel Harris, Aaron Weinberg
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
While T helper (Th) cells play a crucial role in host defense, an imbalance in Th effector subsets due to dysregulation in their differentiation and expansion contribute to inflammatory disorders. Here, we show that Casz1, whose function is previousl
Publikováno v:
Experimental Cell Research. 330:186-198
Cyclin dependent kinase 5 (Cdk5), a proline-directed serine/threonine kinase, requires p39 for its enzymatic activity, and is implicated in cytoskeletal organization and contraction in numerous cell types. The C-terminus of p39 binds muskelin, a mult
Autor:
Joseph D. Weaver, Peggy S. Zelenka, Sonia Gaur, Brajendra K. Tripathi, Ji-Liang Gao, Philip M. Murphy, Erich H. Schneider, Algirdas J. Jesaitis
Publikováno v:
Journal of Biological Chemistry. 287:40779-40792
Lens degeneration in Fpr1(-/-) mice prompted us to search for functional FPR1 expression directly on lens epithelial cells.FPR1 is functionally expressed on human lens epithelial cells but has atypical properties compared with hematopoietic cell FPR1
Autor:
Peggy S. Zelenka, Samuel J. Listwak, Dolena R. Ledee, Leonardo H. Tonelli, Svetlana P. Chapoval, Chad Gunsolly, James D. Nicholson, Daniela Verthelyi, Achsah D. Keegan
Publikováno v:
Journal of Neuroimmunology. 225:82-90
The chemokine CCL27 has chemoattractant properties for memory T cells and has been implicated in skin allergic reactions. The present study reports the expression in the brain of two CCL27 splice variants localized in the cerebral cortex and limbic r
Publikováno v:
Biochemical and Biophysical Research Communications. 354:1034-1039
Cyclin-dependent kinase 5 (Cdk5) has been shown to regulate adhesion and migration of lens and corneal epithelial cells. To explore protein–protein interactions that may mediate these functions, we performed yeast two-hybrid screening on an embryon
Autor:
Janine Smith, Peggy S Zelenka
Publikováno v:
Expert Opinion on Therapeutic Patents. 15:875-887
Cyclin-dependent kinase 5 (CDK5) is generally considered to be a neuron-specific enzyme, and CDK5 inhibitors have most often been claimed for pharmacologic use in neurodegenerative diseases. However, recent findings indicate that CDK5 also has import
Autor:
S. Ray, Chun Gao, Graeme Wistow, Amanda Bundek, Peggy S. Zelenka, Robert N. Fariss, Keith Wyatt
Publikováno v:
Journal of Biological Chemistry. 280:8494-8502
Platelet-derived growth factor D (PDGF-D), also known as Iris-expressed growth factor, is a member of the PDGF/vascular endothelial growth factor family. The expression of PDGF-D in the eye is tissue-specific. In the anterior segment, it is localized
Publikováno v:
Journal of Cell Science. 117:4089-4098
Recent studies have shown that Cdk5, a member of the cyclin-dependent-kinase family, regulates adhesion and migration in a mouse corneal epithelial cell line. Here, we extend these findings to corneal wound healing in vivo and examine the mechanism l
Autor:
Jianguo Fan, Ana B. Chepelinsky, Peggy S. Zelenka, Robert N. Fariss, Nady Golestaneh, Woo Kuen Lo
Publikováno v:
Journal of Biological Chemistry. 279:31813-31822
Lens major intrinsic protein (MIP), exclusive to the vertebrate lens, otherwise known as MIP26 and Aquaporin 0, is abundantly expressed as a lens fiber membrane protein. Although relatively less efficient compared with other aquaporins, MIP is sugges
Autor:
Peggy S. Zelenka
Publikováno v:
The International Journal of Developmental Biology. 48:857-865
Cell movements during lens development and differentiation involve dynamic regulation of cell-matrix and cell-cell adhesion. How these processes are regulated depends on the particular array of matrix components and adhesion proteins that are express