Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Peggy S, Lai"'
Autor:
Long H. Nguyen, Daniel Okin, David A. Drew, Vincent M. Battista, Sirus J. Jesudasen, Thomas M. Kuntz, Amrisha Bhosle, Kelsey N. Thompson, Trenton Reinicke, Chun-Han Lo, Jacqueline E. Woo, Alexander Caraballo, Lorenzo Berra, Jacob Vieira, Ching-Ying Huang, Upasana Das Adhikari, Minsik Kim, Hui-Yu Sui, Marina Magicheva-Gupta, Lauren McIver, Marcia B. Goldberg, Douglas S. Kwon, Curtis Huttenhower, Andrew T. Chan, Peggy S. Lai
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background The gut microbiome is a critical modulator of host immunity and is linked to the immune response to respiratory viral infections. However, few studies have gone beyond describing broad compositional alterations in severe COVID-19,
Externí odkaz:
https://doaj.org/article/afc3763a56b64dd68fea4cc56b2a2b90
Autor:
Michael S. Kelly, MD, Adna Mohammed, BS, Daniel Okin, MD, PhD, George A. Alba, MD, Sirus J. Jesudasen, MD, Shelby Flanagan, MPH, Nupur A. Dandawate, MD, Alexander Gavralidis, MD, Leslie L. Chang, MD, Emily E. Moin, MD, MBE, Alison S. Witkin, MD, Kathryn A. Hibbert, MD, Aran Kadar, MD, Patrick L. Gordan, MD, MBA, Lisa M. Bebell, MD, MSc, Marissa Hauptman, MD, MPH, Linda Valeri, MSc, PhD, Peggy S. Lai, MD, MPH
Publikováno v:
Critical Care Explorations, Vol 5, Iss 6, p e0927 (2023)
IMPORTANCE:. Which social factors explain racial and ethnic disparities in COVID-19 access to care and outcomes remain unclear. OBJECTIVES:. We hypothesized that preferred language mediates the association between race, ethnicity and delays to care.
Externí odkaz:
https://doaj.org/article/962529ccd7824a428b7a6fbf9550c310
Autor:
Mehdi Benamar, Qian Chen, Janet Chou, Amélie M. Julé, Rafik Boudra, Paola Contini, Elena Crestani, Peggy S. Lai, Muyun Wang, Jason Fong, Shira Rockwitz, Pui Lee, Tsz Man Fion Chan, Ekin Zeynep Altun, Eda Kepenekli, Elif Karakoc-Aydiner, Ahmet Ozen, Perran Boran, Fatih Aygun, Pinar Onal, Ayse Ayzit Kilinc Sakalli, Haluk Cokugras, Metin Yusuf Gelmez, Fatma Betul Oktelik, Esin Aktas Cetin, Yuelin Zhong, Maria Lucia Taylor, Katherine Irby, Natasha B. Halasa, Elizabeth H. Mack, Overcoming COVID-19 Investigators, Sara Signa, Ignazia Prigione, Marco Gattorno, Nicola Cotugno, Donato Amodio, Raif S. Geha, Mary Beth Son, Jane Newburger, Pankaj B. Agrawal, Stefano Volpi, Paolo Palma, Ayca Kiykim, Adrienne G. Randolph, Gunnur Deniz, Safa Baris, Raffaele De Palma, Klaus Schmitz-Abe, Louis-Marie Charbonnier, Lauren A. Henderson, Talal A. Chatila
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 1 (2023)
Multisystem inflammatory syndrome in children (MIS-C) evolves in some pediatric patients following acute infection with SARS-CoV-2 by hitherto unknown mechanisms. Whereas acute-COVID-19 severity and outcomes were previously correlated with Notch4 exp
Externí odkaz:
https://doaj.org/article/a39c807bcee64be782682857c935eead
Autor:
Jacob Vieira, Sirus Jesudasen, Lindsay Bringhurst, Hui-Yu Sui, Lauren McIver, Katrine Whiteson, Kurt Hanselmann, George A. O’Toole, Christopher J. Richards, Leonard Sicilian, Isabel Neuringer, Peggy S. Lai
Publikováno v:
mSystems, Vol 7, Iss 5 (2022)
ABSTRACT Features of the airway microbiome in persons with cystic fibrosis (pwCF) are correlated with disease progression. Microbes have traditionally been classified for their ability to tolerate oxygen. It is unknown whether supplemental oxygen, a
Externí odkaz:
https://doaj.org/article/e56270e82f7548a19eaf598d09d68c21
Autor:
Mark J Siedner, Francis Bajunirwe, David B Meya, Lisa Liang Philpotts, Peggy S Lai, Joseph Baruch Baluku, Edwin Nuwagira, Stella G Mpagama
Publikováno v:
BMJ Open, Vol 12, Iss 8 (2022)
Introduction Tuberculosis (TB) is significantly associated with multiple postinfectious, non-communicable diseases after microbiological cure. For example, those with a history of TB disease have a higher risk of developing chronic lung diseases at a
Externí odkaz:
https://doaj.org/article/daee91f7c4f74163a471e8e149978d0d
Autor:
Emily E. Moin, Daniel Okin, Sirus J. Jesudasen, Nupur A. Dandawate, Alexander Gavralidis, Leslie L. Chang, Alison S. Witkin, Kathryn A. Hibbert, Aran Kadar, Patrick L. Gordan, Lisa M. Bebell, Peggy S. Lai, George A. Alba
Publikováno v:
Resuscitation Plus, Vol 10, Iss , Pp 100219- (2022)
Purpose: Code status orders impact clinical outcomes as well as patients’ and surrogates’ experiences. This is the first multicenter cohort examining code status orders of ICU patients with COVID-19 reported to date. Materials and methods: This i
Externí odkaz:
https://doaj.org/article/fb92cc4be5ff4d999539e40116468a8b
Autor:
Crystal M. North, Piers MacNaughton, Peggy S. Lai, Jose Vallarino, Samson Okello, Bernard Kakuhikire, Alexander C. Tsai, Marcia C. Castro, Mark J. Siedner, Joseph G. Allen, David C. Christiani
Publikováno v:
Environmental Health, Vol 18, Iss 1, Pp 1-12 (2019)
Abstract Background Most of the global burden of pollution-related morbidity and mortality is believed to occur in resource-limited settings, where HIV serostatus and sex may influence the relationship between air pollution exposure and respiratory m
Externí odkaz:
https://doaj.org/article/51f8f4c4c68d4fa6b498c301c9d732a9
Autor:
Andres Cardenas, Joanne E. Sordillo, Sheryl L. Rifas-Shiman, Wonil Chung, Liming Liang, Brent A. Coull, Marie-France Hivert, Peggy S. Lai, Erick Forno, Juan C. Celedón, Augusto A. Litonjua, Kasey J. Brennan, Dawn L. DeMeo, Andrea A. Baccarelli, Emily Oken, Diane R. Gold
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Epigenetic differences in nasal epithelium have been proposed as a biomarker for lower airway disease and asthma. Here, in epigenome-wide association studies for asthma and other airway traits using nasal swabs, the authors identify differentially me
Externí odkaz:
https://doaj.org/article/463a3a6559c24a0d94c1e260b9956f71
Autor:
Daniel, Okin, Ching-Ying, Huang, George A, Alba, Sirus J, Jesudasen, Nupur A, Dandawate, Alexander, Gavralidis, Leslie L, Chang, Emily E, Moin, Imama, Ahmad, Alison S, Witkin, C Corey, Hardin, Kathryn A, Hibbert, Aran, Kadar, Patrick L, Gordan, Hang, Lee, B Taylor, Thompson, Lisa M, Bebell, Peggy S, Lai
Publikováno v:
Chest. 163:533-542
Prone position ventilation (PPV) is resource-intensive, yet the optimal strategy for PPV in intubated patients with COVID-19 is unclear.Does a prolonged (24 or more hours) PPV strategy improve mortality in intubated COVID-19 patients compared to inte
Autor:
Ana A Weil, Meti D Debela, Daniel M Muyanja, Bernard Kakuhikire, Charles Baguma, David R Bangsberg, Alexander C Tsai, Peggy S Lai
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0252261 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0229699.].
Externí odkaz:
https://doaj.org/article/8d09bdffe3d947ae9317b537e7a05d59