Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Peggy Lu"'
Autor:
Peggy Lu, Francesco Alletto, Bosul Lee, Elizabeth Burk, Jasmine Martinez, Fabio Prati, Emilia Caselli, Brad Spellberg, Brian Luna
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0287102 (2023)
Recently, we reported rifabutin hyper-activity against Acinetobacter baumannii. We sought to characterize if any additional rifamycins (n = 22) would also display hyper-activity when tested in iron-limited media against A. baumannii, K. pneumoniae, a
Externí odkaz:
https://doaj.org/article/ad60d1ef5d15411eb99a26636e488cc0
Autor:
Marlène Maeusli, Nicholas Skandalis, Bosul Lee, Peggy Lu, Sarah Miller, Jun Yan, Yuli Talyansky, Rachel Li, Zeferino Reyna, Noel Guerrero, Amber Ulhaq, Matthew Slarve, Ioannis Theologidis, Brad Spellberg, Brian Luna
Publikováno v:
mSphere, Vol 7, Iss 3 (2022)
ABSTRACT Novel approaches to combating antibiotic resistance are needed given the ever-continuing rise of antibiotic resistance and the scarce discovery of new antibiotics. Little is known about the colonization dynamics and the role of intrinsic pla
Externí odkaz:
https://doaj.org/article/0295be0ddbe94d329abb045df3f02088
Autor:
Bosul Lee, Jun Yan, Amber Ulhaq, Sarah Miller, Wonjae Seo, Peggy Lu, Rosemary She, Brad Spellberg, Brian Luna
Publikováno v:
mSphere, Vol 6, Iss 6 (2021)
ABSTRACT We recently reported that the antimicrobial activity of rifabutin against Acinetobacter baumannii is best modeled by the use of RPMI for in vitro susceptibility testing. Here, we define the effects of medium on the susceptibility and frequen
Externí odkaz:
https://doaj.org/article/d93849aae744420f96a3fc927649b5f7
Autor:
Marlène Maeusli, Bosul Lee, Sarah Miller, Zeferino Reyna, Peggy Lu, Jun Yan, Amber Ulhaq, Nicholas Skandalis, Brad Spellberg, Brian Luna
Publikováno v:
mSphere, Vol 5, Iss 3 (2020)
ABSTRACT Agricultural use of antibiotics is recognized by the U.S. Centers for Disease Control and Prevention as a major contributor to antibiotic-resistant infections. While most One Health attention has been on the potential for antibiotic resistan
Externí odkaz:
https://doaj.org/article/cba93b122e474db59beeb97cbbc37e6f
Autor:
Brian M Luna, Jun Yan, Zeferino Reyna, Eugene Moon, Travis B Nielsen, Hernan Reza, Peggy Lu, Robert Bonomo, Arnold Louie, George Drusano, Jürgen Bulitta, Rosemary She, Brad Spellberg
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219824 (2019)
In 2017, the WHO identified Acinetobacter baumannii as the top priority for the development of new antibiotics. Despite the need for new antibiotics, there remains a lack of well validated preclinical tools for A. baumannii. Here, we characterize and
Externí odkaz:
https://doaj.org/article/bc06e2509ee34e9294fd5e940445f5a3
Autor:
Yuanyuan Jiao, Jun Yan, Michael Vicchiarelli, Dhruvitkumar S. Sutaria, Peggy Lu, Zeferino Reyna, Brad Spellberg, Robert A. Bonomo, George L. Drusano, Arnold Louie, Brian M. Luna, Jürgen B. Bulitta
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
Polymyxin B is a “last-line-of-defense” antibiotic approved in the 1960s. However, the population pharmacokinetics (PK) of its four main components has not been reported in infected mice. We aimed to determine the PK of polymyxin B1, B1-Ile, B2,
Autor:
Peggy, Lu, Alletto, Francesco, Lee, Bosul, Burk, Elizabeth, Martinez, Jasmine, Prati, Fabio, Caselli, Emilia, Spellberg, Brad, Luna, Brian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3674::aae91eb7062a5fcca97392f294946099
https://hdl.handle.net/11380/1308786
https://hdl.handle.net/11380/1308786
Autor:
Amber Ulhaq, Brian Luna, Jun Yan, Peggy Lu, Bosul Lee, Brad Spellberg, Sarah Miller, Wonjae Seo, Rosemary C. She
Publikováno v:
mSphere, Vol 6, Iss 6 (2021)
mSphere
mSphere
We recently reported that the antimicrobial activity of rifabutin against Acinetobacter baumannii is best modeled by the use of RPMI for in vitro susceptibility testing. Here, we define the effects of medium on the susceptibility and frequency of res
Autor:
Travis B. Nielsen, Elizabeth Burk, Brian Luna, Matthew Slarve, Peter Oelschlaeger, William Win, Kyle Hurth, Robert A. Bonomo, Yuli Talyansky, Rachel Li, Bosul Lee, Peggy Lu, Brad Spellberg, Juan Ruiz, Jun Yan
Publikováno v:
Infect Immun
Extremely drug-resistant (XDR) Acinetobacter baumannii is a notorious and frequently encountered pathogen demanding novel therapeutic interventions. An initial monoclonal antibody (MAb), C8, raised against A. baumannii capsule, proved a highly effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2811835ce749a36edb72a8f341828c80
https://europepmc.org/articles/PMC8445169/
https://europepmc.org/articles/PMC8445169/
Autor:
Amber Ulhaq, Zeferino Reyna, Brian Luna, Peggy Lu, Marlène Maeusli, Nicholas Skandalis, Brad Spellberg, Jun Yan, Bosul Lee, Sarah Miller
Publikováno v:
mSphere
mSphere, Vol 5, Iss 3, p e00329-20 (2020)
mSphere, Vol 5, Iss 3, p e00329-20 (2020)
Previous efforts have correlated antibiotic-fed livestock and meat products with respective antibiotic resistance genes, but virtually no research has been conducted on the transmission of antibiotic resistance from plant foods to the mammalian gut (