Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Peggy Kegley"'
Autor:
Ashraf Badros, R. Donald Harvey, Rong Chen, Tianling Chen, Kristi Mahadocon, Judith A. Fox, Rajni Sinha, David A. Siegel, Wei Gang Tong, William G. Wierda, Peggy Kegley, William Plunkett, Ute Hoch, Steven Coutre, Leslie Popplewell
Publikováno v:
Journal of Clinical Oncology. 28:3015-3022
Purpose SNS-032 is a highly selective and potent inhibitor of cyclin-dependent kinases (Cdks) 2, 7, and 9, with in vitro growth inhibitory effects and ability to induce apoptosis in malignant B cells. A phase I dose-escalation study of SNS-032 was co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8981c13073e88950685fb01f3fbf61
https://doi.org/10.1200/jco.2009.26.1347
https://doi.org/10.1200/jco.2009.26.1347
Autor:
Kristi Mahadocon, Steven Coutre, Mary G. Bolton, Peggy Kegley, R. Donald Harvey, David S. Siegel, William Plunkett, Rajni Sinha, Judith A. Fox, Runzhe Chen, Leslie Popplewell, William G. Wierda, Ashraf Badros
Publikováno v:
Blood. 112:3178-3178
SNS-032, formerly BMS-387032, is a highly selective and potent inhibitor of cyclin-dependent kinases (CDK) 2, 7 and 9. CDK2 and CDK7 are involved in cell cycle regulation. CDK7, along with CDK9, regulate RNA polymerase (Pol) II-dependent transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::534f9d6b074a4682f05410ac4232eca7
https://doi.org/10.1182/blood.v112.11.3178.3178
https://doi.org/10.1182/blood.v112.11.3178.3178