Výsledky vyhledávání - "Peggy J. Pula"

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Autor: Tony E. Hugli, Arthur M. Dannenberg, Masahiro Nakamura, Fujiho Tanaka, Kazuyuki Higuchi, Peggy J. Pula, Donald L. Kreutzer, Richard G. Discipio

Publikováno v: Inflammation. 21:251-267

Developing, peak and healing lesions were induced in the skin of rabbits by topical applications (on different days) of the chemical irritant sulfur mustard (SM). Immediately after the rabbits were euthanized, the intact lesions were excised and orga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c4b48b8973622b92cac7a8c515f262ee
https://doi.org/10.1023/a:1027378422627

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Extracellular Collagenase, Proteoglycanase and Products of Their Activity, Released in Organ Culture by Intact Dermal Inflammatory Lesions Produced by Sulfur Mustard

Autor: Masahiro Nakamura, Nancy M. Dahms, Janet S. Kerr, J. Frederick Woessner, Gerald W. Hart, Peggy J. Pula, Akira Kajiki, Kazuyuki Higuchi, Marie G. Selzer, Arthur M. Dannenberg, Carol L. Ruppert

Publikováno v: Journal of Investigative Dermatology. 95(6):717-726

Peak (1 and 2 d) and healing (3, 6, and 10 d) inflammatory lesions were produced in rabbits by the topical application of the military vesicant, bis(2-chloroethyl)sulfide, commonly called sulfur mustard (SM). SM produces an acute sterile dermal infla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1a43b30183d9d42aa5b01862eba33f

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Full-Thickness Human Skin Explants for Testing the Toxicitiy of Topically Applied Chemicals

Autor: Takafumi Yano, Masahiro Nakamura, Peggy J. Pula, Toru Rikimaru, Brian Schofield, Arthur M. Dannenberg, K. Gregory Moore

Publikováno v: Journal of Investigative Dermatology. 95(3):325-332

This report describes a model organ-culture system for testing the toxicity of chemical substances that are topically applied to human skin. In this system, the viable keratinocytes in the full-thickness skin explants are protected by the same kerati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18f97d4e64264eb95ca8a526ddf277b

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Two Sensitive in Vitro Monitors of Chemical Toxicity to Human and Animal Skin (in Short-Term Organ Culture): I. Paranuclear Vacuolization in glycol Methacrylate Tissue Sections II. Interference with [14C]Leucine Incorporation

Autor: Akira Kajiki, K. Gregory Moore, Kazuwki Higuchi, Peggy J. Pula, D. J. P. Bassett, Arthur M. Dannenberg, Brian Schofield, Kin Wing Au

Publikováno v: Journal of Toxicology: Cutaneous and Ocular Toxicology. 5:285-302

Two sensitive in vitro tests have been developed to determine the toxicity of chemicals applied to full-thickness skin explants from fresh human surgical specimens and sacrificed guinea pigs and rabbits. Before incubation, dinitrochlorobenzene (DNCB)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8355a3627da9967e9acba738625d872
https://doi.org/10.3109/15569528609036302

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Sources of extracellular lysosomal enzymes released in organ-culture by developing and healing inflammatory lesions

Autor: Peggy J. Pula, Akira Kajiki, Kazuyuki Higuchi, Arthur M. Dannenberg, Louis H. Liu, Masahiro Nakamura

Publikováno v: Journal of leukocyte biology. 43(2)

Developing and healing inflammatory lesions were topically produced in the skin of rabbits by sulfur mustard (SM). After the rabbits were sacrificed, the various lesions were removed and organ-cultured. The organ-culture fluids extracted the extracel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e327d860edaaabab9464998daba8e608
https://pubmed.ncbi.nlm.nih.gov/3422085

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