Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Peggy J. Farnham"'
Autor:
Alex de Mendoza, Trung Viet Nguyen, Ethan Ford, Daniel Poppe, Sam Buckberry, Jahnvi Pflueger, Matthew R. Grimmer, Sabine Stolzenburg, Ozren Bogdanovic, Alicia Oshlack, Peggy J. Farnham, Pilar Blancafort, Ryan Lister
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-31 (2022)
Abstract Background Cytosine DNA methylation is widely described as a transcriptional repressive mark with the capacity to silence promoters. Epigenome engineering techniques enable direct testing of the effect of induced DNA methylation on endogenou
Externí odkaz:
https://doaj.org/article/b7e0ceb7c87f42b496fd72cdb8d5a2de
Autor:
Suhn Kyong Rhie, Andrew A. Perez, Fides D. Lay, Shannon Schreiner, Jiani Shi, Jenevieve Polin, Peggy J. Farnham
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
In prostate cancer, chromatin structure can impact the transcriptome. Here, the authors develop high resolution chromatin interaction maps in prostate cancer cells using in situ Hi-C, revealing prostate cancer-specific TADs and enhancer-promoter loop
Externí odkaz:
https://doaj.org/article/bf4333a7da084e70ab3ac3f87cbcc657
Autor:
Henriette O’Geen, Sofie L. Bates, Sakereh S. Carter, Karly A. Nisson, Julian Halmai, Kyle D. Fink, Suhn K. Rhie, Peggy J. Farnham, David J. Segal
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-20 (2019)
Abstract Background Rewriting of the epigenome has risen as a promising alternative to gene editing for precision medicine. In nature, epigenetic silencing can result in complete attenuation of target gene expression over multiple mitotic divisions.
Externí odkaz:
https://doaj.org/article/f99d86a8bbaf4fed912b9c90925d2dd9
Autor:
Yu Guo, Andrew A. Perez, Dennis J. Hazelett, Gerhard A. Coetzee, Suhn Kyong Rhie, Peggy J. Farnham
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-17 (2018)
Abstract Background Recent genome-wide association studies (GWAS) have identified more than 100 loci associated with increased risk of prostate cancer, most of which are in non-coding regions of the genome. Understanding the function of these non-cod
Externí odkaz:
https://doaj.org/article/9bcba50014fa4bf2876aa1d3ed808387
Publikováno v:
Cell Reports, Vol 21, Iss 6, Pp 1411-1417 (2017)
Summary: Prostate cancer (PCa) is the leading cancer among men in the United States, with genetic factors contributing to ∼42% of the susceptibility to PCa. We analyzed a PCa risk region located at 7p15.2 to gain insight into the mechanisms by whic
Externí odkaz:
https://doaj.org/article/fd814044b8b445789dbb4f737987c0b2
Autor:
Luis G. Acevedo, A. Leonardo Iniguez, Heather L. Holster, Xinmin Zhang, Roland Green, Peggy J. Farnham
Publikováno v:
BioTechniques, Vol 43, Iss 6, Pp 791-797 (2007)
The technique of chromatin immunoprecipitation (ChIP) is a powerful method for identifying in vivo DNA binding sites of transcription factors and for studying chromatin modifications. Unfortunately, the large number of cells needed for the standard C
Externí odkaz:
https://doaj.org/article/b79bb0905027428d95dc427f7323cda0
Publikováno v:
BioTechniques, Vol 41, Iss 5, Pp 577-580 (2006)
A single chromatin immunoprecipitation (ChIP) sample does not provide enough DNA for hybridization to a genomic tiling array. A commonly used technique for amplifying the DNA obtained from ChIP assays is ligation-mediated PCR (LM-PCR). However, using
Externí odkaz:
https://doaj.org/article/7158a1050435478d91d69fb270e9de4d
Autor:
Mark Zern, Peggy J. Farnham, Ralph W. de vere White, Natalie J. Torok, Candice Tahimic, Joy X. Jiang, Kimberly R. Blahnik, Sushma Iyengar, Christine J. Jung
PDF file - 12K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f64293e880961cfffcfc021b1c96339
https://doi.org/10.1158/1541-7786.22517689.v1
https://doi.org/10.1158/1541-7786.22517689.v1
Autor:
Mark Zern, Peggy J. Farnham, Ralph W. de vere White, Natalie J. Torok, Candice Tahimic, Joy X. Jiang, Kimberly R. Blahnik, Sushma Iyengar, Christine J. Jung
XLS file - 42K, KEGG Pathway Categories of Differentially Up-Regulated Genes Following EHCC miRNA Expression in hPHs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea27722cc3ac14a7aee6ce0c451ecc2
https://doi.org/10.1158/1541-7786.22517683.v1
https://doi.org/10.1158/1541-7786.22517683.v1
Autor:
Mark Zern, Peggy J. Farnham, Ralph W. de vere White, Natalie J. Torok, Candice Tahimic, Joy X. Jiang, Kimberly R. Blahnik, Sushma Iyengar, Christine J. Jung
PDF file - 1.3MB, S1. Pearson correlation analysis of hESCs, HCCs and hPHS. S2. EHCC miRNAs are not capable of rescuing hepatic progenitor cell induction in Dgcr8 null mESCs during the in vitro differentiation process of mESCs along a hepatic lineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc45379f77c97c74da9e095126d6715
https://doi.org/10.1158/1541-7786.22517686.v1
https://doi.org/10.1158/1541-7786.22517686.v1