Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Peggy I. Wang"'
Autor:
Andrej J Savol, Peggy I Wang, Yesu Jeon, David Colognori, Eda Yildirim, Stefan F Pinter, Bernhard Payer, Jeannie T Lee, Ruslan I Sadreyev
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182568 (2017)
In mammals, monoallelic gene expression can result from X-chromosome inactivation, genomic imprinting, and random monoallelic expression (RMAE). Epigenetic regulation of RMAE is not fully understood. Here we analyze allelic imbalance in chromatin sta
Externí odkaz:
https://doaj.org/article/d2fb6aac590144e1a7065ef3104958b4
Autor:
Sarah K Bowman, Aimee M Deaton, Heber Domingues, Peggy I Wang, Ruslan I Sadreyev, Robert E Kingston, Welcome Bender
Publikováno v:
eLife, Vol 3 (2014)
The bithorax complex (BX-C) in Drosophila melanogaster is a cluster of homeotic genes that determine body segment identity. Expression of these genes is governed by cis-regulatory domains, one for each parasegment. Stable repression of these domains
Externí odkaz:
https://doaj.org/article/8473f4313b264f1680854a28ddd03e3a
Autor:
Clifford J. Tabin, Sharmistha Kundu, Sharon K. Marr, Ruslan I. Sadreyev, Peggy I. Wang, Andrej J. Savol, Matthew G. Schwartz, Daniel J. Grau, Patrick Schorderet, Robert E. Kingston, Mei Sheng Lau
Publikováno v:
Science. 355:1081-1084
Polycomb group gene silencing Histone proteins wrap around DNA to form nucleosomes that package metazoan DNA into the nucleus. Chromatin compaction is also believed to be critical for the repression of homeotic genes by the Polycomb repressive comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b8a8bba1e08f492c70f543203520073
https://doi.org/10.1126/science.aah5403
https://doi.org/10.1126/science.aah5403
Autor:
Robert E. Kingston, Jakub Mieczkowski, Peggy I. Wang, Sharmistha Kundu, Ruslan I. Sadreyev, Britta Mueller, Michael Y. Tolstorukov
Publikováno v:
Genes & Development. 31:451-462
Activation of transcription requires alteration of chromatin by complexes that increase the accessibility of nucleosomal DNA. Removing nucleosomes from regulatory sequences has been proposed to play a significant role in activation. We tested whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bdcb3fb2722a1279c54a1cde3ce487d
https://doi.org/10.1101/gad.293118.116
https://doi.org/10.1101/gad.293118.116
Autor:
Steven Tropello, Howard Carolan, Daniel J. Sheets, Aliaksei Pustavoitau, R. Gentry Wilkerson, Peggy I. Wang, Nolan Benner, Clark Fischer
Publikováno v:
Journal of Medical Devices. 13
This paper describes a novel percutaneous ultrasound gastrostomy (PUG) procedure and the CoapTech point-of-care ultrasound magnet-aligned gastrostomy (PUMA-G) device, which were developed to allow the placement of gastrostomy tubes by physicians acro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3a9b5494c349c0f1a6514d21daa0d9a
https://doi.org/10.1115/1.4042866
https://doi.org/10.1115/1.4042866
Autor:
Shawn T. Brown, Joel Gittelsohn, Michelle S. Wong, Eli Zenkov, Yeeli Mui, Peggy I. Wang, Atif Adam, Marie C. Ferguson, Bruce Y. Lee, Daniel L. Hertenstein
A number of locations have been considering sugar-sweetened beverage point-of-purchase warning label policies to help address rising adolescent overweight and obesity prevalence.To explore the impact of such policies, in 2016 detailed agent-based mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247e4819a865e56f0f9de79d6c04e62a
https://europepmc.org/articles/PMC5783749/
https://europepmc.org/articles/PMC5783749/
Autor:
Lawrence J. Cheskin, Michelle S. Wong, Atif Adam, Daniel L. Hertenstein, Bruce Y. Lee, Marie C. Ferguson, Peggy I. Wang, Patrick T. Wedlock, Sindiso Nyathi, Saeideh Falah-Fini, Shawn T. Brown, Joel Gittelsohn, Eli Zenkov, Sarah M. Bartsch
Increasing physical activity among children is a potentially important public health intervention. Quantifying the economic and health effects of the intervention would help decision makers understand its impact and priority. Using a computational si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4d5e79833dd832273690ab5c1ec9b2
https://europepmc.org/articles/PMC5563819/
https://europepmc.org/articles/PMC5563819/
Autor:
Christopher P. Davis, Robert E. Kingston, Matthew D. Simon, Hongjae Sunwoo, Jason A. West, Peggy I. Wang, Ruslan I. Sadreyev, Michael Y. Tolstorukov
Publikováno v:
Molecular Cell. 55:791-802
Mechanistic roles for many lncRNAs are poorly understood, in part because their direct interactions with genomic loci and proteins are difficult to assess. Using a method to purify endogenous RNAs and their associated factors, we mapped the genomic b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f464134386e6000ee0dfe5b86946ece
https://doi.org/10.1016/j.molcel.2014.07.012
https://doi.org/10.1016/j.molcel.2014.07.012
Autor:
Anthony Anselmo, Brian C. Del Rosario, Peggy I. Wang, Jeannie T. Lee, Ruslan I. Sadreyev, Amanda M. Del Rosario
Publikováno v:
Developmental cell. 43(3)
Summary X-chromosome inactivation (XCI) silences one X chromosome in the female mammal and is essential to peri-implantation development. XCI is thought to be cell autonomous, with all factors required being produced within each cell. Nevertheless, e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8affe2947b8bc3c828e2a49d2ba9077a
https://pubmed.ncbi.nlm.nih.gov/29107559
https://pubmed.ncbi.nlm.nih.gov/29107559
Publikováno v:
Genome Research
Network “guilt by association” (GBA) is a proven approach for identifying novel disease genes based on the observation that similar mutational phenotypes arise from functionally related genes. In principle, this approach could account even for no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959dcabd905ff214e8fd9b0fcacb5898
https://doi.org/10.1101/gr.118992.110
https://doi.org/10.1101/gr.118992.110