Výsledky vyhledávání - "Peggy Del Carmine"

Akademický článek

Haploinsufficiency of autism spectrum disorder candidate gene NUAK1 impairs cortical development and behavior in mice

Autor: Virginie Courchet, Amanda J. Roberts, Géraldine Meyer-Dilhet, Peggy Del Carmine, Tommy L. Lewis, Franck Polleux, Julien Courchet

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)

Nuak1 is an autism spectrum disorder candidate gene. Here the authors report behavioral and cortical development in mice heterozygous for Nuak1, suggesting loss of function mutations in one copy of Nuak1 may contribute to neurodevelopmental disorders

Externí odkaz: https://doaj.org/article/86a0b1965c3547f0820ef0dd3daf13b6

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Heparan Sulfate Mimetics Accelerate Postinjury Skeletal Muscle Regeneration

Autor: Jessica Bouvière, Sébastien Banzet, Aurélie Trignol, Dieu-Huong Hoang, Bénédicte Chazaud, Peggy Del Carmine, Denis Barritault, Marie-Emmanuelle Goriot, Sabrina Ben Larbi

Publikováno v: Tissue Engineering Part A. 25:1667-1676

Although skeletal muscle is capable of complete recovery after an injury, specific situations require support or acceleration of this process, such as in the elderly and athletes, respectively. Skeletal muscle regeneration is due to muscle stem cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f55ca6fe7b7433ec7c1a92da2044279
https://doi.org/10.1089/ten.tea.2019.0058

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Individualized isometric neuromuscular electrical stimulation training promotes myonuclear accretion in mouse skeletal muscle

Autor: Aliki Zavoriti, Aurélie Fessard, Masoud Rahmati, Peggy Del Carmine, Bénédicte Chazaud, Julien Gondin

Skeletal muscle is a plastic tissue that adapts to exercise through fusion of muscle stem cells (MuSCs) with myofibers, a physiological process referred to as myonuclear accretion. However, it is still unclear whether myonuclear accretion is driven b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73511836f577f59bfe6a6f59045082a6
https://doi.org/10.1101/2021.12.14.472254

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Thyroid hormone receptor-α deletion decreases heart function and exercise performance in apolipoprotein E-deficient mice

Autor: Ming Lo, Karine Gauthier, Michel Beylot, Peggy del Carmine, Laurence Canaple, Kiao Ling Liu

Publikováno v: Physiological Genomics. 48:73-81

The deletion of thyroid hormone receptor-α (TRα) in atherosclerosis-prone apolipoprotein E-deficient (ApoE−/−) mice (ApoE−/−TRα0/0) accelerates the formation of atherosclerotic plaques without aggravation of hypercholesterolemia. To evalua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f17b36b1a0c2053cee6bac2e70d82e
https://doi.org/10.1152/physiolgenomics.00115.2015

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Haploinsufficiency of autism candidate gene NUAK1 impairs cortical development and behavior

Autor: Franck Polleux, Amanda J. Roberts, Virginie Courchet, Tommy L. Lewis, Peggy Del Carmine, Julien Courchet

Publikováno v: bioRxiv

SUMMARYRecently, numerous rare de novo mutations have been identified in children diagnosed with autism spectrum disorders (ASD). However, despite the predicted loss-of-function nature of some of these de novo mutations, the affected individuals are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0fc8e40179681a75cca4aea90660a05
https://doi.org/10.1101/262725

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Regulation of Akt-mTOR, ubiquitin-proteasome and autophagy-lysosome pathways in locomotor and respiratory muscles during experimental sepsis in mice

Autor: Julien Gondin, Serge Molliex, Josiane Castells, Thierry Busso, Damien Freyssenet, David Arnould, Anne Cécile Durieux, Peggy Del Carmine, Jerome Morel, Jean-Charles Palao, Vanessa E. Jahnke, Marine Desgeorges

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7 (1), ⟨10.1038/s41598-017-11440-5⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)

Sepsis induced loss of muscle mass and function contributes to promote physical inactivity and disability in patients. In this experimental study, mice were sacrificed 1, 4, or 7 days after cecal ligation and puncture (CLP) or sham surgery. When comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b1731c0cd67a951d2936347988dca20
http://europepmc.org/articles/PMC5589872

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TRα Protects Against Atherosclerosis in Male Mice: Identification of a Novel Anti-Inflammatory Property for TRα in Mice

Autor: Jacques Samarut, Alexandre Deloire, Laurence Canaple, Karine Gauthier, Cyrielle Billon, Sébastien Fleury, M. Beylot, David Dombrowicz, Peggy del Carmine

Publikováno v: Endocrinology
Endocrinology, Endocrine Society, 2014, 155 (7), pp.2735-2745. ⟨10.1210/en.2014-1098⟩
Endocrinology, 2014, 155 (7), pp.2735-2745. ⟨10.1210/en.2014-1098⟩

International audience; Hypothyroidism is associated with an increased occurrence of atherosclerosis, suggesting some protective role for thyroid hormones (THs). Hypercholesterolemia is one of the major risk factor to develop this disease. Here, we s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102258abab287e8be69a06976d07b0f9
https://doi.org/10.1210/en.2014-1098

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Nonalcoholic Hepatic Steatosis in Zucker Diabetic Rats: Spontaneous Evolution and Effects of Metformin and Fenofibrate

Autor: Michel Beylot, Alexandra Basset, Peggy del Carmine, Ghina Haffar, Fabien Forcheron, Pauline Abdallah

Publikováno v: Obesity. 17:1381-1389

No specific treatment for nonalcoholic hepatic fatty liver disease has been defined. We followed the spontaneous evolution of liver steatosis and tested the therapeutic usefulness of metformin and fenofibrate in a model of steatosis, the Zucker diabe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0bfe06c57ee97127bcb8f416946d59
https://doi.org/10.1038/oby.2008.661

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Adiponectin receptors: expression in Zucker diabetic rats and effects of fenofibrate and metformin

Autor: Coralie Metais, Michel Beylot, Giampiero Bricca, Fabien Forcheron, Peggy del Carmine, Alexandra Basset, Pauline Abdallah

Publikováno v: Metabolism. 57:946-953

The insulin-sensitizing adipokine, adiponectin, acts through 2 receptors, AdipoR1 and AdipoR2. A decreased expression of these receptors could contribute to insulin resistance and diabetes. We determined if the expression of adiponectin receptors is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0126b2fd4900eb4d8827564d2dfc82e3
https://doi.org/10.1016/j.metabol.2008.02.010

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Vascular function of the mesenteric artery isolated from thyroid hormone receptor-alpha Knockout mice

Autor: Kiao Ling Liu, Ming Lo, Peggy del Carmine, Karine Gauthier, Michel Beylot, Laurence Canaple

Publikováno v: Journal of Vascular Research
Journal of Vascular Research, Karger, 2014, 51 (5), pp.350-359. ⟨10.1159/000368195⟩
Journal of Vascular Research, 2014, 51 (5), pp.350-359. ⟨10.1159/000368195⟩

Objective: This study evaluated the consequences of thyroid hormone receptor-E (TRE) disruption on vascular reactivity. Methods: The activity of superior mesenteric arteries isolated from TRE knockout mice generated in the SV129 background (TRE0/0SV)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564cb0d4376981a9f273c87c53cd237a
https://hal.inrae.fr/hal-02634799

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