Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Peggy A. Scherle"'
Autor:
Rebecca S. Cook, Holly K. Koblish, Peggy A. Scherle, Justin M. Balko, Jamaal L. James, Mellissa J. Nixon, Paula I. Gonzales-Ericsson, Violeta Sanchez, Donna J. Hicks, Bushra Rahman, David L. Elion, Thomas A. Werfel
Efferocytosis is the process by which apoptotic cells are cleared from tissue by phagocytic cells. The removal of apoptotic cells prevents them from undergoing secondary necrosis and releasing their inflammation-inducing intracellular contents. Effer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a7c8a9839e99a391d54de44b1f8950a
https://doi.org/10.1158/0008-5472.c.6510818.v1
https://doi.org/10.1158/0008-5472.c.6510818.v1
Autor:
Rebecca S. Cook, Holly K. Koblish, Peggy A. Scherle, Justin M. Balko, Jamaal L. James, Mellissa J. Nixon, Paula I. Gonzales-Ericsson, Violeta Sanchez, Donna J. Hicks, Bushra Rahman, David L. Elion, Thomas A. Werfel
Supplemental Figure S6. Tumors harvested on treatment d 7 were assessed by IHC for FoxP3 and Arg-1. Representative images are shown. Original magnification = 400X. Asterisks represent areas of acellular debris. Black arrows indicate tumor infiltratin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b391b6002fd2de78471ae232ce1fdf3
https://doi.org/10.1158/0008-5472.22421027
https://doi.org/10.1158/0008-5472.22421027
Autor:
Peggy A. Scherle, Robert C. Newton, Wenqing Yao, Jincong Zhuo, Meizhong Xu, Chunhong He, Sharon Diamond, Jason Boer, Yu Li, Richard Wynn, Elham Behshad, Jordan S. Fridman, Leslie M. Hall, Holly K. Koblish, Cindy Marando, Gengjie Yang, Qian Wang, Xiangdong Liu
PDF file - 91K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e2ac65557a6da0e73230a1e910ea93
https://doi.org/10.1158/1078-0432.22443831.v1
https://doi.org/10.1158/1078-0432.22443831.v1
Autor:
Peggy A. Scherle, Robert C. Newton, Wenqing Yao, Jincong Zhuo, Meizhong Xu, Chunhong He, Sharon Diamond, Jason Boer, Yu Li, Richard Wynn, Elham Behshad, Jordan S. Fridman, Leslie M. Hall, Holly K. Koblish, Cindy Marando, Gengjie Yang, Qian Wang, Xiangdong Liu
PDF file - 94K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38dc9ab0796303e073ea0830c1554ad1
https://doi.org/10.1158/1078-0432.22443834
https://doi.org/10.1158/1078-0432.22443834
Autor:
Peggy A. Scherle, Robert C. Newton, Wenqing Yao, Jincong Zhuo, Meizhong Xu, Chunhong He, Sharon Diamond, Jason Boer, Yu Li, Richard Wynn, Elham Behshad, Jordan S. Fridman, Leslie M. Hall, Holly K. Koblish, Cindy Marando, Gengjie Yang, Qian Wang, Xiangdong Liu
PDF file - 66K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a72bf8abaf13e94800645d9e3c5eb8d
https://doi.org/10.1158/1078-0432.22443828
https://doi.org/10.1158/1078-0432.22443828
Autor:
Jun Li, Margaret Favata, Jennifer A. Kelley, Eian Caulder, Beth Thomas, Xiaoming Wen, Richard B. Sparks, Ari Arvanitis, James D. Rogers, Andrew P. Combs, Kris Vaddi, Kimberly A. Solomon, Peggy A. Scherle, Robert Newton, Jordan S. Fridman
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 1, Pp 28-38 (2010)
Cytokines in the bone marrow of multiple myeloma patients activate Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathways in tumor cells and promote tumor growth, survival, and drug resistance. INCB16562 was dev
Externí odkaz:
https://doaj.org/article/8ff70b38f3cd4dcba837d81f78e72017
Autor:
Jeffrey Kaufman, Koichi Ito, Kris Vaddi, Joseph Rager, Peggy A. Scherle, Jack Carter, Bruce Ruggeri, Nicole Spardy Burr, Neha Bhagwat, Venkat Thodima
Publikováno v:
Cancer Research. 81:1138-1138
Adenoid cystic carcinoma (ACC) is a rare cancer of secretory glands, characterized by slow and unpredictable growth, unrelenting relapse and high rates of metastasis. Poor response to chemotherapy and targeted drugs has resulted in there being no app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06e2ea0a7ea22341d8653d56527958b9
https://doi.org/10.1158/1538-7445.am2021-1138
https://doi.org/10.1158/1538-7445.am2021-1138
Autor:
Koichi Ito, Alexander Grego, Mizue Terai, Peggy A. Scherle, Bruce Ruggeri, Jack Carter, Neha Bhagwat, Joseph Rager, Venkat Thodima, Takami Sato, Omar Abdel-Wahab, Monisha Sivakumar, Kris Vaddi
Publikováno v:
Cancer Research. 81:1137-1137
PRMT5 (protein arginine methyltransferase 5) is a predominant Type II PRMT that catalyzes symmetric dimethylation of protein arginine residues (sDMA). PRMT5 is overexpressed in many types of cancer and plays roles in multiple essential biological pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c662b45f75ae9a9ce3e25431f5245e0
https://doi.org/10.1158/1538-7445.am2021-1137
https://doi.org/10.1158/1538-7445.am2021-1137
Autor:
Monisha Sivakumar, Youyou Zhang, Kris Vaddi, Jacob Spruance, Lin Zhang, Bruce Ruggeri, Koichi Ito, Venkat Thodima, Mu Xu, Peggy A. Scherle, Joseph Rager, Jack Carter, Neha Bhagwat
Publikováno v:
Cancer Research. 81:1185-1185
Genetic defects of DNA damage response (DDR) pathways in cancer cells induce synthetic lethality with chemotherapy and PARP inhibitors. However, many patients with advanced cancers develop resistance to these therapies mainly due to circumvention and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33e43ac50d29bc7c60388a02a4c2570b
https://doi.org/10.1158/1538-7445.am2021-1185
https://doi.org/10.1158/1538-7445.am2021-1185
Autor:
Robert J. Cherney, Peggy A. Scherle, Matthew E. Voss, Persymphonie B. Miller, Qihong Zhao, Gengjie Yang, Sarah R. King, Gregory D. Brown, Sandhya Mandlekar, Carl P. Decicco, Percy H. Carter, Andrew J. Tebben, Yvonne C. Lo
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:3311-3316
We describe an isostere-driven approach to improve upon a previously-described series of capped dipeptide antagonists of CC Chemokine Receptor 2 (CCR2). Modification of the substitution around the isostere was combined with additional changes in a di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7950fbb3a84435ceb2f0d4bd997371d
https://doi.org/10.1016/j.bmcl.2012.03.007
https://doi.org/10.1016/j.bmcl.2012.03.007