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of 4
pro vyhledávání: '"Pegcantratinib"'
Autor:
Cranston, Amy, Stocken, Deborah D., Stamp, Elaine, Roblin, David, Hamlin, Julia, Langtry, James, Plummer, Ruth, Ashworth, Alan, Burn, John, Rajan, Neil
Publikováno v:
Trials
Background Patients with germline mutations in a tumour suppressor gene called CYLD develop multiple, disfiguring, hair follicle tumours on the head and neck. The prognosis is poor, with up to one in four mutation carriers requiring complete surgical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::615e9efbf15a9fb3a715996a5a926e4c
Autor:
Monique, Zangarini, Neil, Rajan, Marina, Danilenko, Philip, Berry, Silvio, Traversa, Gareth J, Veal
Publikováno v:
Bioanalysis
Aim: Pegcantratinib is a mini-PEGylated K252a derivative, under clinical evaluation as an anticancer agent acting through inhibition of the tropomyosin receptor kinase. A method for quantifying pegcantratinib in skin tumor biopsies of patients was re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4504cee3993df704ec1f522b6faa7b44
https://pubmed.ncbi.nlm.nih.gov/28111963
https://pubmed.ncbi.nlm.nih.gov/28111963
Akademický článek
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Autor:
Cranston A; Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, NE2 4AE, UK. amy.cranston@ncl.ac.uk., Stocken DD; Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, NE2 4AE, UK.; Institute of Health and Society, Newcastle University, Newcastle upon Tyne, NE2 4AX, UK., Stamp E; Institute of Health and Society, Newcastle University, Newcastle upon Tyne, NE2 4AX, UK., Roblin D; The Francis Crick Institute, London, NW1 2BE, UK., Hamlin J; Ziarco Pharma Ltd, Innovation House, Ramsgate Road, Sandwich, Kent, CT13 9ND, UK., Langtry J; Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, NE1 4LP, UK., Plummer R; Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK., Ashworth A; UCSF Helen Diller Family Comprehensive Cancer Centre, San Francisco, CA, 94158, USA., Burn J; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, NE1 3BZ, UK., Rajan N; Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, NE1 4LP, UK.; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, NE1 3BZ, UK.
Publikováno v:
Trials [Trials] 2017 Mar 07; Vol. 18 (1), pp. 111. Date of Electronic Publication: 2017 Mar 07.