Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Pegah Safabakhsh"'
Autor:
Tinne Verhulst, Lieven Meerpoel, Emmanuel Gustin, Weimei Sun, Matthew V. Lorenzi, Junchen Gu, Longen Zhou, Wim Bert Griet Schepens, Hillary Millar, Tongfei Wu, Viellevoye Marcel, Vineet Pande, Petra Vinken, Desiree De Lange, An Boeckx, Christopher Moy, Friederike Pastore, Geert Mannens, Sylvie Laquerre, Ulrike Philippar, Vipul Bhargava, Gaston Stanislas Marcella Diels, Thomas Nys, Kathryn Packman, Jan Willem Thuring, Erika van Heerde, Bie Verbist, Sumit Rai, Lijs Beke, Pegah Safabakhsh, Timothy A. Graubert, Yue Fan, Angelique N Gilbert, Dirk Brehmer, Vikki Keersmaekers, Barbara Morschhäuser, Danilo Fiore, David Walker, Amy J. Johnson
Publikováno v:
Molecular cancer therapeutics. 20(12)
The protein arginine methyltransferase 5 (PRMT5) methylates a variety of proteins involved in splicing, multiple signal transduction pathways, epigenetic control of gene expression, and mechanisms leading to protein expression required for cellular p
Autor:
Bin Fang, Erika R. Briggs, Ying Wu, David J. Steger, Mete Civelek, Mitchell A. Lazar, Raymond E. Soccio, Pegah Safabakhsh, Eric Chen, Benjamin F. Voight, Kyoung-Jae Won, Logan J. Everett, Matthew J. Emmett, Hee-Woong Lim, Satyajit R. Rajapurkar, Joanna R. DiSpirito, Jill M. Marinis
Publikováno v:
Cell. 162(1):33-44
SummarySNPs affecting disease risk often reside in non-coding genomic regions. Here, we show that SNPs are highly enriched at mouse strain-selective adipose tissue binding sites for PPARγ, a nuclear receptor for anti-diabetic drugs. Many such SNPs a
Autor:
Michael Schaffer, Ted Laderas, Brian J. Druker, Pegah Safabakhsh, Fei Huang, Shannon K. McWeeney, Yoko Kosaka, Homer Adams, Clare Lefave, Lauren K. Brady, Adam J. Lamble, David Soong, Evan F. Lind, Brendan P. Hodkinson, Yann Abraham, Jeffrey W. Tyner
Publikováno v:
Blood. 132:2750-2750
Advances in Acute Myeloid Leukemia (AML) research have shown that the bone marrow microenvironment may distinctly vary across disease subtypes, and that this variation is associated with disease risk and response to conventional therapies. Novel ther
Autor:
Christiaan J. M. Saris, Guang Xian Zhang, Abdolmohamad Rostami, Melissa Cullimore, Pegah Safabakhsh, Denise C. Fitzgerald, Zoe Fonseca-Kelly
Publikováno v:
The Journal of Immunology. 190:3225-3234
IFN-β, IL-27, and IL-10 have been shown to exert a range of similar immunoregulatory effects in murine and human experimental systems, particularly in Th1- and Th17-mediated models of autoimmune inflammatory disease. In this study we sought to trans