Zobrazeno 1 - 10 of 95 pro vyhledávání: '"Peffers, MJ"'
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Identification of Candidate Synovial Fluid Biomarkers for the Prediction of Patient Outcome following Microfracture or Osteotomy
Autor: Hulme, CH, Peffers, MJ, Harrington, GMB, Wilson, E, Perry, J, Roberts, S, Gallacher, P, Jermin, P, Wright Bevans, K
Background: Biomarkers are needed to predict clinical outcome for microfracture and osteotomy surgeries to ensure patients can be better stratified to receive the most appropriate treatment. \ud Hypothesis/purpose: To identify novel biomarker candida
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::04068cf9d6ccd366659567d1d2f85264
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7
Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro
Autor: Rubio-Martinez, LM, Rioja, E, Martins, M Castro, Wipawee, S, Clegg, P, Peffers, MJ
Publikováno v: BMC Veterinary Research
Arthritis Research and Therapy
BMC Veterinary Research, Vol 13, Iss 1, Pp 1-8 (2017)
BMC VETERINARY RESEARCH
Background Chondrotoxic effects of local anaesthetics are well reported in humans and some animal species but knowledge on their toxic effects on synoviocytes or equine chondrocytes or the effects on cellular production of inflammatory cytokines is l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fd2729e675fd618406693b6647bd6082
http://europepmc.org/articles/PMC5678813
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8
Serum snoRNAs as biomarkers for joint ageing and post traumatic osteoarthritis
Autor: Steinbusch, MMF, Fang, Y, Milner, PI, Clegg, PD, Young, DA, Welting, TJM, Peffers, MJ
Publikováno v: Scientific Reports, 7:43558. Nature Publishing Group
Scientific reports
The development of effective treatments for the age-related disease osteoarthritis and the ability to predict disease progression has been hampered by the lack of biomarkers able to demonstrate the course of the disease. Profiling the expression patt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b3170af537b0cf0573d19c52a9dcdfb1
https://cris.maastrichtuniversity.nl/en/publications/c84712e6-0aec-4d58-85cd-4fcf47a4a3a9
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9
A proteomic analysis of chondrogenic, osteogenic and tenogenic constructs from ageing mesenchymal stem cells
Autor: Peffers, MJ, Collins, J, Loughlin, J, proctor, C, Clegg, P
Publikováno v: Stem Cell Research & Therapy
Background Mesenchymal stem cells (MSCs) have prospective applications in regenerative medicine and tissue engineering but to what extent phenotype and differentiation capacity alter with ageing is uncertain. Consequently, any loss in functionality w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6745f37e97392c2dc7acb7e79d8cf0
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10
Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq
Autor: Peffers, MJ, Goljanek-Whysall, K, Collins, J, Fang, Y, Rushton, M, Loughlin, J, Proctor, C, Clegg, PD
Publikováno v: PLoS ONE, Vol 11, Iss 8, p e0160517 (2016)
PLoS ONE
PLOS ONE
Mesenchymal stem cells (MSC) are capable of multipotent differentiation into connective tissues and as such are an attractive source for autologous cell-based regenerative medicine and tissue engineering. Epigenetic mechanisms, like DNA methylation,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0ffb769b4c9abd385ce2cacd87aced08
https://doaj.org/article/14ea65a0420642e8aaeaacb51e680a5c
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