Výsledky vyhledávání

Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

Autor: Borrow, P, Lewicki, H, Wei, X, Horwitz, MS, Peffer, N, Meyers, H, Nelson, JA, Gairin, JE, Hahn, BH, Oldstone, MB, Shaw, GM

The HIV-1-specific cytotoxic T lymphocyte (CTL) response is temporally associated with the decline in viremia during primary HIV-1 infection, but definitive evidence that it is of importance in virus containment has been lacking. Here we show that in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7bbfdc98b68822498ab284e55d2493ad
https://ora.ox.ac.uk/objects/uuid:0c801680-9f44-47c4-8d27-f8fbf95fdf20

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The enhancer domain of the human cytomegalovirus major immediate-early promoter determines cell type-specific expression in transgenic mice

Autor: Baskar, J F, Smith, P P, Nilaver, G, Jupp, R A, Hoffmann, S, Peffer, N J, Tenney, D J, Colberg-Poley, A M, Ghazal, P, Nelson, J A

Publikováno v: Baskar, J F, Smith, P P, Nilaver, G, Jupp, R A, Hoffmann, S, Peffer, N J, Tenney, D J, Colberg-Poley, A M, Ghazal, P & Nelson, J A 1996, ' The enhancer domain of the human cytomegalovirus major immediate-early promoter determines cell type-specific expression in transgenic mice ', Journal of Virology, vol. 70, no. 5, pp. 3207-14 . < http://jvi.asm.org/content/70/5/3207 >

The human cytomegalovirus (HCMV) major immediate-early promoter (MIEP) is one of the first promoters to activate upon infection. To examine HCMV MIEP tissue-specific expression, transgenic mice were established containing the lacZ gene regulated by t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::66e58628572758bf7d1375e01ff6ab31
https://hdl.handle.net/20.500.11820/39fb6d38-3e8e-4261-989d-433da8b50510

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Akademický článek

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Akademický článek

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Direct activation of human resting T cells by IL 2: the role of an IL 2 receptor distinct from the Tac protein

Autor: Bich-Thuy, L. T., Dukovich, M., Peffer, N. J., Fauci, A. S., John Kehrl, Greene, W. C.

Publikováno v: Scopus-Elsevier

High concentrations of interleukin 2 (IL 2) were shown to produce a delayed but pronounced proliferation of purified resting T cells in the apparent absence of other activation signals. Because these stimulatory effects of IL 2 occurred in the absenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1864e81929639f03cd6e8d54981fba1
https://doi.org/10.4049/jimmunol.139.5.1550

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Periodical

Interleukin 2 receptor gene expression in normal human T lymphocytes.

Autor: Leonard, W J, Krönke, M, Peffer, N J, Depper, J M, Greene, W C

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; September 1985, Vol. 82 Issue: 18 p6281-6285, 5p

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Periodical

Strand-invasion of duplex DNA by peptide nucleic acid oligomers.

Autor: Peffer, N J, Hanvey, J C, Bisi, J E, Thomson, S A, Hassman, C F, Noble, S A, Babiss, L E

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; November 1993, Vol. 90 Issue: 22 p10648-10652, 5p

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Periodical

Sequence requirements for ligand binding and cell surface expression of the Tac antigen, a human interleukin-2 receptor.

Autor: Cullen, B R, Podlaski, F J, Peffer, N J, Hosking, J B, Greene, W C

Publikováno v: Journal of Biological Chemistry; April 1988, Vol. 263 Issue: 10 p4900-4906, 7p

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Periodical

The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression.

Autor: Ballard, D W, Dixon, E P, Peffer, N J, Bogerd, H, Doerre, S, Stein, B, Greene, W C

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; March 1992, Vol. 89 Issue: 5 p1875-1879, 5p

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Periodical

Induction of Interleukin-2 Receptor-α Gene Expression Is Regulated by Post-translational Activation of κ B Specific DNA Binding Proteins

Autor: Böhnlein, E, Ballard, D W, Bogerd, H, Peffer, N J, Lowenthal, J W, Greene, W C

Publikováno v: Journal of Biological Chemistry; May 1989, Vol. 264 Issue: 15 p8475-8478, 4p

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