Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Peer Wuensche"'
Autor:
Yun Zheng, Kian Leong Lee, Henry Yang, Peer Wuensche, Ling-Wen Ding, Makoto Sudo, Wenwen Chien, Norimichi Hattori, Manoj Garg, Seiichi Mori, Erkan Baloglu, Sharon Shacham, Qiao-Yang Sun, Sigal Gery, H. Phillip Koeffler, Michael Kauffman, Sarawut Wongphayak, Liang Xu
Publikováno v:
Journal of Cancer
This study is an unbiased genomic screen to obtain functional targets for increased effectiveness of dasatinib in pancreatic cancer. Dasatinib, a multi-targeted tyrosine kinase inhibitor, is used in clinical trials for treatment of pancreatic cancer;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae864c04e14497e629f146d9a1bc903
https://pubmed.ncbi.nlm.nih.gov/30588262
https://pubmed.ncbi.nlm.nih.gov/30588262
Autor:
Seiichi Mori, Itay Tokatly, Wenwen Chien, Henry Yang, Ling-Wen Ding, Qiao-Yang Sun, H. Phillip Koeffler, Jeffrey W. Tyner, Siew Zhuan Tan, Kian Leong Lee, Peer Wuensche, Lorenz Poellinger, Lucia A. Torres-Fernandez, Norazean Zaiden
Publikováno v:
Molecular Oncology. 9:889-905
We utilized three tiers of screening to identify novel therapeutic agents for pancreatic cancers. First, we analyzed 14 pancreatic cancer cell lines against a panel of 66 small‐molecule kinase inhibitors and dasatinib was the most potent. Second, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c99de34403158c58bdc79af18a42880
https://doi.org/10.1016/j.molonc.2015.01.002
https://doi.org/10.1016/j.molonc.2015.01.002
Autor:
Ahmed M. Aribi, Yun Zheng, Ding Ling Wen, H. Phillip Koeffler, Wenwen Chien, Su Ming Thean, Dhong Hyun Lee, Rosie Alvarez, Jonathan W. Said, Ngan B. Doan, Peer Wuensche
Publikováno v:
Molecular Carcinogenesis. 53:722-735
Pancreatic ductal adenocarcinoma is a devastating disease with few therapeutic options. Histone deacetylase inhibitors are a novel therapeutic approach to cancer treatment; and two new pan-histone deacetylase inhibitors (HDACi), belinostat and panobi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18e494ef08113f900fd49b4c14d94bbf
https://doi.org/10.1002/mc.22024
https://doi.org/10.1002/mc.22024
Autor:
Peer Wuensche, Wenwen Chien, Jonathan W. Said, H P Koeffler, Kian Leong Lee, Ngan B. Doan, Ling-Wen Ding, H Kato, Lorenz Poellinger
Publikováno v:
British journal of cancer, vol 109, iss 7
British Journal of Cancer
British Journal of Cancer
Background: The PIAS4 protein belongs to the family of protein inhibitors of activated STAT, but has since been implicated in various biological activities including the post-translational modification known as sumoylation. In this study, we explored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb94084925086278ffb98eb4885fd2b
https://escholarship.org/uc/item/3p73v3kq
https://escholarship.org/uc/item/3p73v3kq
Autor:
Makoto Sudo, Peer Wuensche, Wenwen Chien, Qiao-Yang Sun, Kian Leong Lee, Lorenz Poellinger, Jeffrey W. Tyner, Henry Yang, H. Phillip Koeffler
Publikováno v:
Cancer Research. 73:1291-1291
Tyrosine kinase inhibitors (TKIs) have provided promising anti-cancer activities, but intrinsic or acquired resistance to these drugs is a major problem. To overcome this resistance, we have used microarray analysis to identify a signature of intrins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c9ca9942f77fe84eae5ffb3c28dbfac
https://doi.org/10.1158/1538-7445.am2013-1291
https://doi.org/10.1158/1538-7445.am2013-1291