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Autor:
Iris F. Ueki, Birgit Jung, Peer Kroschel, Jae Jeong Shim, Pierre-Régis Burgel, Ursula Protin, Jay A. Nadel, Trang Dao-Pick, Kiyoshi Takeyama
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 280:L165-L172
Mucus hypersecretion from hyperplastic airway goblet cells is a hallmark of chronic obstructive pulmonary disease (COPD). Although cigarette smoking is thought to be involved in mucus hypersecretion in COPD, the mechanism by which cigarette smoke ind