Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Peer B. Jacobson"'
Autor:
Andrea J. Mothe, Peer B. Jacobson, Mitchell Caprelli, Antigona Ulndreaj, Radmehr Rahemipour, Lili Huang, Philippe P. Monnier, Michael G. Fehlings, Charles H. Tator
Publikováno v:
Neurobiology of Disease, Vol 172, Iss , Pp 105812- (2022)
Spinal cord injury (SCI) elicits a cascade of degenerative events including cell death, axonal degeneration, and the upregulation of inhibitory molecules which limit repair. Repulsive guidance molecule A (RGMa) is an axon growth inhibitor which is al
Externí odkaz:
https://doaj.org/article/a8245c7e74194fe69378e5a56161daca
Autor:
Peer B. Jacobson, Robin Goody, Matthew Lawrence, Bernhard K. Mueller, Xiaomeng Zhang, Bradley A. Hooker, Kimberly Pfleeger, Adam Ziemann, Charles Locke, Quentin Barraud, Mathias Droescher, Joerg Bernhard, Andreas Popp, Preethne Boeser, Lili Huang, Jennifer Mollon, Yulia Mordashova, Yi-Fang Cui, John P. Savaryn, Christine Grinnell, Ingeborg Dreher, Michael Gold, Grégoire Courtine, Andrea Mothe, Charles H. Tator, James D. Guest
Publikováno v:
Neurobiology of Disease, Vol 155, Iss , Pp 105385- (2021)
Spinal cord injury (SCI) is a devastating condition characterized by loss of function, secondary to damaged spinal neurons, disrupted axonal connections, and myelin loss. Spontaneous recovery is limited, and there are no approved pharmaceutical treat
Externí odkaz:
https://doaj.org/article/8dc4097a8c454ae6bfbbc5ad5984d8ca
Autor:
Andrea J. Mothe, Marlon Coelho, Lili Huang, Philippe P. Monnier, Yi-Fang Cui, Bernhard K. Mueller, Peer B. Jacobson, Charles H. Tator
Publikováno v:
Neurobiology of Disease, Vol 143, Iss , Pp 104995- (2020)
Spinal cord injury (SCI) often results in permanent functional loss due to a series of degenerative events including cell death, axonal damage, and the upregulation of inhibitory proteins that impede regeneration. Repulsive Guidance Molecule A (RGMa)
Externí odkaz:
https://doaj.org/article/0705e8cb2a934da099c36c454f69f541
Autor:
Sarath P. Gunasekera, Anne M. Romanic, Peer B. Jacobson, Michael J. Fay, Mary Hall, Renee Peksa, Marcio Guzman, Alejandro M. S. Mayer
Publikováno v:
Marine Drugs, Vol 5, Iss 3, Pp 113-135 (2007)
The excitatory amino acid domoic acid is the causative agent of amnesic shellfish poisoning in humans. The in vitro effects of domoic acid on rat neonatal brain microglia were compared with E. coli lipopolysaccharide (LPS), a known activator of micro
Externí odkaz:
https://doaj.org/article/ab8018e40ba949bfae804cdfc7dfaeec
Autor:
Elaine Smith, Ingeborg Dreher, Mathias Droescher, Bradley A Hooker, Jennifer Mollon, Xiaomeng Zhang, Peer B Jacobson
Publikováno v:
Stroke. 54
Introduction: Current acute interventions for ischemic stroke aim to restore perfusion of affected tissue. There is an unmet need for therapies that protect neurons from ischemic damage and/or enhance natural repair processes to restore function. In
Autor:
Dustin R. Wakeman, Michael R. Weed, Sylvia E. Perez, Erika N. Cline, Kirsten L. Viola, Kyle C. Wilcox, David S. Moddrelle, Ernell Z. Nisbett, Anish M. Kurian, Amanda F. Bell, Ricaldo Pike, Peer B. Jacobson, William L. Klein, Elliott J. Mufson, Matthew S. Lawrence, John D. Elsworth
Publikováno v:
Neuropathology and applied neurobiologyREFERENCES. 48(4)
An obstacle to developing new treatment strategies for Alzheimer's disease (AD) has been the inadequate translation of findings in current AD transgenic rodent models to the prediction of clinical outcomes. By contrast, nonhuman primates (NHPs) share
Autor:
Yi-Fang Cui, Bernhard K. Mueller, Charles H. Tator, Philippe P. Monnier, Peer B. Jacobson, Marlon Coelho, Lili Huang, Andrea J. Mothe
Publikováno v:
Neurobiology of Disease, Vol 143, Iss, Pp 104995-(2020)
Spinal cord injury (SCI) often results in permanent functional loss due to a series of degenerative events including cell death, axonal damage, and the upregulation of inhibitory proteins that impede regeneration. Repulsive Guidance Molecule A (RGMa)
Autor:
Peer B. Jacobson, Melanie Scott, Paul M. Jung, Jason J. Winnick, Alan D. Cherrington, Rita Basu, Dale S. Edgerton, Joshua Roop, Viswanathan Saraswathi, Christopher J. Ramnanan
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 304:E747-E756
The aim of this study was to determine the effect of prolonged 11β-hydroxysteroid dehydrogenase-1 (11β-HSD1) inhibition on basal and hormone-stimulated glucose metabolism in fasted conscious dogs. For 7 days prior to study, either an 11β-HSD1 inhi
Autor:
Chih-Hung Lee, Ann Tovcimak, Michael W. Decker, Gerard B. Fox, Gricelda H. Simler, Prisca Honore, Jordan W. Brown, Chang Z. Zhu, Madhavi Pai, Nathan R. Rustay, Chih-Liang Chin, Chengmin Zhong, Joe Mikusa, Murali Gopalakrishnan, Victoria A. Komater, Donna M. Gauvin, Anita K. Salyers, Scott J. Baker, La Geisha Lewis, Peer B. Jacobson, Erica Gomez, Prasant Chandran
Publikováno v:
Biochemical Pharmacology. 82:967-976
Positive modulation of the neuronal nicotinic acetylcholine receptor (nAChR) α4β2 subtype by selective positive allosteric modulator NS-9283 has shown to potentiate the nAChR agonist ABT-594-induced anti-allodynic activity in preclinical neuropathi
Autor:
Rita Basu, Michael Sarr, Robert A. Rizza, Paul M. Jung, Peer B. Jacobson, Michael D. L. Johnson, Meagan M Grudzien, Ravinder J. Singh, Ananda Basu
Publikováno v:
Diabetes
OBJECTIVE—To determine the contribution of liver and viscera to splanchnic cortisol production in humans. RESEARCH DESIGN AND METHODS—D4 cortisol was infused intravenously; arterial, portal venous, and hepatic venous blood was sampled; and liver