Zobrazeno 1 - 3
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pro vyhledávání: '"Pedro de Andrade Horn"'
Publikováno v:
The Journal of Organic Chemistry. 87:8796-8801
A nickel-catalyzed tandem Ueno-Stork cyclization is developed to enable stereoselective 1,2-dicarbofunctionalization of cyclic alkenes and efficiently build various bicyclic products. This new protocol does not involve any toxic or difficult-to-remov
Dissertation/ Thesis
A historically important reaction, the Ueno-Stork reaction promotes, through the use of toxic organotin species, the cyclization of a haloacetal onto an alkene generating bicyclic acetals. This reaction has been used over the years in several total s
Autor:
Jing-Yuan Liu, Jian Ting Zhang, Robert C. Peery, Pedro de Andrade Horn, Kwaku Kyei-Baffour, Jianguo Liu, Zizheng Dong, Mingji Dai
Publikováno v:
J Med Chem
Survivin, a homodimeric member of the Inhibitor of Apoptosis Protein (IAP) family, is required for cancer cell survival and overexpressed in almost all solid tumors. However, targeting survivin has been challenging due to its "undruggable" nature. Re