Výsledky vyhledávání - "Pedro V. da Silva-Neto"

Akademický článek

Plasma Sphingomyelin Disturbances: Unveiling Its Dual Role as a Crucial Immunopathological Factor and a Severity Prognostic Biomarker in COVID-19

Publikováno v: Cells, Vol 12, Iss 15, p 1938 (2023)

SARS-CoV-2 infection triggers distinct patterns of disease development characterized by significant alterations in host regulatory responses. Severe cases exhibit profound lung inflammation and systemic repercussions. Remarkably, critically ill patie

Externí odkaz: https://doaj.org/article/08327d39112b4723bd7923540f24fd0a

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

The Interplay among Glucocorticoid Therapy, Platelet-Activating Factor and Endocannabinoid Release Influences the Inflammatory Response to COVID-19

Publikováno v: Viruses, Vol 15, Iss 2, p 573 (2023)

COVID-19 is associated with a dysregulated immune response. Currently, several medicines are licensed for the treatment of this disease. Due to their significant role in inhibiting pro-inflammatory cytokines and lipid mediators, glucocorticoids (GCs)

Externí odkaz: https://doaj.org/article/8571dd7050f54f5e89a23cd7c0e0bc72

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

The Severity of COVID-19 Affects the Plasma Soluble Levels of the Immune Checkpoint HLA-G Molecule

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 17, p 9736 (2022)

The non-classical histocompatibility antigen G (HLA-G) is an immune checkpoint molecule that has been implicated in viral disorders. We evaluated the plasma soluble HLA-G (sHLA-G) in 239 individuals, arranged in COVID-19 patients (n = 189) followed u

Externí odkaz: https://doaj.org/article/dc3221bc80fa471baea141889c67a91e

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Matrix Metalloproteinases on Severe COVID-19 Lung Disease Pathogenesis: Cooperative Actions of MMP-8/MMP-2 Axis on Immune Response through HLA-G Shedding and Oxidative Stress

Publikováno v: Biomolecules, Vol 12, Iss 5, p 604 (2022)

Patients with COVID-19 predominantly have a respiratory tract infection and acute lung failure is the most severe complication. While the molecular basis of SARS-CoV-2 immunopathology is still unknown, it is well established that lung infection is as

Externí odkaz: https://doaj.org/article/a4761d57afc64085bf12c2d1efb8f8ed

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

sTREM-1 Predicts Disease Severity and Mortality in COVID-19 Patients: Involvement of Peripheral Blood Leukocytes and MMP-8 Activity

Autor: Pedro V. da Silva-Neto, Jonatan C. S. de Carvalho, Vinícius E. Pimentel, Malena M. Pérez, Diana M. Toro, Thais F. C. Fraga-Silva, Carlos A. Fuzo, Camilla N. S. Oliveira, Lilian C. Rodrigues, Jamille G. M. Argolo, Ingryd Carmona-Garcia, Nicola T. Neto, Camila O. S. Souza, Talita M. Fernandes, Victor A. F. Bastos, Augusto M. Degiovani, Leticia F. Constant, Fátima M. Ostini, Marley R. Feitosa, Rogerio S. Parra, Fernando C. Vilar, Gilberto G. Gaspar, José J. R. da Rocha, Omar Feres, Fabiani G. Frantz, Raquel F. Gerlach, Sandra R. Maruyama, Elisa M. S. Russo, Angelina L. Viana, Ana P. M. Fernandes, Isabel K. F. M. Santos, Vânia L. D. Bonato, Antonio L. Boechat, Adriana Malheiro, Ruxana T. Sadikot, Marcelo Dias-Baruffi, Cristina R. B. Cardoso, Lúcia H. Faccioli, Carlos A. Sorgi, on behalf of the IMUNOCOVID Study Group

Publikováno v: Viruses, Vol 13, Iss 12, p 2521 (2021)

Uncontrolled inflammatory responses play a critical role in coronavirus disease (COVID-19). In this context, because the triggering-receptor expressed on myeloid cells-1 (TREM-1) is considered an intrinsic amplifier of inflammatory signals, this stud

Externí odkaz: https://doaj.org/article/11ff9cf45f4e4d15bd09faff571b2561

Zobrazit plný text záznamu

Plný text ve formátu HTML

Acetylcholine, Fatty Acids, and Lipid Mediators Are Linked to COVID-19 Severity

Publikováno v: The Journal of Immunology. 209:250-261

Lipid and cholinergic mediators are inflammatory regulators, but their role in the immunopathology of COVID-19 is still unclear. Here, we used human blood and tracheal aspirate (TA) to investigate whether acetylcholine (Ach), fatty acids (FAs), and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f965a5346c56b2e1dcc281d907b97fe
https://doi.org/10.4049/jimmunol.2200079

Zobrazit plný text záznamu

Prognostic value of sTREM-1 in COVID-19 patients: a biomarker for disease severity and mortality

Autor: Vinicius E Pimentel, Thais Fernanda de Campos Fraga-Silva, Angelo A.F. Junior, Marcelo Dias-Baruffi, Rita C.C. Barbieri, Elisa Maria de Sousa Russo, Rogério Serafim Parra, Kamila Zaparoli, Nicola T. Neto, Vania L. D. Bonato, Giovanna S. Porcel, Leticia F. Constant, Omar Féres, Cassia F. S. L. Dias, Fernando Crivelenti Vilar, Ana Paula Morais Fernandes, José Joaquim Ribeiro da Rocha, Fatima M. Ostini, Marley Ribeiro Feitosa, Caroline T. Garbato, Rafael C. da Silva, Augusto M. Degiovani, Fabiani Gai Frantz, Adriana Malheiro, Jamille Guedes Malta Argolo, Jonatan C S de Carvalho, Isabelle C. Guarneri, Malena M. Perez, Carlos Arterio Sorgi, Lilian Cataldi Rodrigues, Diana Mota Toro, Debora C. Nepomuceno, Ruxana T. Sadikot, Alessandro P de Amorim, Camilla Narjara Simão Oliveira, Cristina Ribeiro de Barros Cardoso, Dayane P. da Silva, Cristiane M. Milanezi, Lúcia Helena Faccioli, Pedro V da Silva Neto, Isabel Kinney Ferreira de Miranda Santos, Ana C. Xavier, Angelina Lettiere Viana, Ingryd Carmona-Garcia, Gilberto Gambero Gaspar, Sandra Regina Maruyama

BackgroundThe uncontrolled inflammatory response plays a critical role in the novel coronavirus disease (COVID-19) and triggering receptor expressed on myeloid cells-1 (TREM-1) is thought to be intricate to inflammatory signal amplification. This stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da9aa1a5969983e6e3485d71142969a1
https://doi.org/10.1101/2020.09.22.20199703

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání