Enhancing Dental Pulp Stem Cell Proliferation and Odontogenic Differentiation with Protein Phosphatase 1-Disrupting Peptide: An In Vitro Study

Autor: Anna Kobrock, Bárbara Matos, Daniela Patrício, Liliana Grenho, John Howl, Margarida Fardilha, Pedro S. Gomes

Publikováno v: Cells, Vol 13, Iss 13, p 1143 (2024)

The reparative and regenerative capabilities of dental pulp stem cells (DPSCs) are crucial for responding to pulp injuries, with protein phosphatase 1 (PP1) playing a significant role in regulating cellular functions pertinent to tissue healing. Acco

Externí odkaz: https://doaj.org/article/5b6eb8779dbf4083b6360366d0583c0c

Assuring the Biofunctionalization of Silicone Covalently Bonded to Rhamnolipids: Antibiofilm Activity and Biocompatibility

Autor: Maïssa Dardouri, Ana Bettencourt, Victor Martin, Filomena A. Carvalho, Bruno Colaço, Adelina Gama, Madeleine Ramstedt, Nuno C. Santos, Maria H. Fernandes, Pedro S. Gomes, Isabel A. C. Ribeiro

Publikováno v: Pharmaceutics, Vol 14, Iss 9, p 1836 (2022)

Silicone-based medical devices composed of polydimethylsiloxane (PDMS) are widely used all over the human body (e.g., urinary stents and catheters, central venous catheters stents) with extreme clinical success. Nevertheless, their abiotic surfaces,

Externí odkaz: https://doaj.org/article/cf0fef31eac24c0090ebc924d9413b76

The Osteogenic Assessment of Mineral Trioxide Aggregate–based Endodontic Sealers in an Organotypic Ex Vivo Bone Development Model

Autor: Maria Helena Fernandes, Bruno Colaço, Pedro S. Gomes, Bruna Pinheiro

Publikováno v: Journal of Endodontics. 47:1461-1466

Introduction Mineral trioxide aggregate (MTA)-based sealers are endodontic materials with widespread success in distinct clinical applications, potentially embracing direct contact with the bone tissue. Bone response to these materials has been tradi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e718096646df9a0f19f347bb1925cd
https://doi.org/10.1016/j.joen.2021.06.006

Assessment of the bone healing process mediated by periosteum-derived mesenchymal stem cells’ secretome and a xenogenic bioceramic - an in vivo study in the rabbit critical size calvarial defect model

Autor: Milda Alksne, Mindaugas Pranskunas, Pedro S. Gomes, Victor Martin, Egidijus Šimoliūnas, Gintaras Juodzbalys, Algirdas Kaupinis, Algirdas Puisys

Publikováno v: Materials, Basel : MDPI AG, 2021, vol. 14, no. 13, art. no. 3512, p. 133-149
Materials
Volume 14
Issue 13
Materials, Vol 14, Iss 3512, p 3512 (2021)

The mesenchymal stem cell (MSC) secretome has been considered an innovative therapeutic biological approach, able to modulate cellular crosstalk and functionality for enhanced tissue repair and regeneration. This study aims to evaluate the functional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80f45327b9216ffd1319e47e129b32a
https://repository.vu.lt/VU:ELABAPDB152554405&prefLang=en_US

Microgap and bacterial microleakage during the osseointegration period: An in vitro assessment of the cover screw and healing abutment in a platform-switched implant system

Autor: João C. Sampaio-Fernandes, Pedro Ferrás Fernandes, Liliana Grenho, Pedro S. Gomes, Maria Helena Fernandes

Publikováno v: The Journal of Prosthetic Dentistry.

Statement of problem Microgap and bacterial microleakage at the implant-prosthetic abutment interface are recognized concerns for implant-supported restorations, leading to inflammation of the peri-implant tissues, with deleterious consequences for c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e211267986de91002f55667027364cd
https://doi.org/10.1016/j.prosdent.2021.07.030