Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Pedro S. Lazo"'
Autor:
Lucia Cabal-Hierro, Lorea J Ugarte-Gil, Noelia Artime, Miguel A. Prado, Bryant G. Darnay, Pedro Casado, J. Iglesias, Pedro S. Lazo, Belén Fernández-García
Publikováno v:
Oncotarget
Tumor Necrosis Factor (TNF) interacts with two receptors known as TNFR1 and TNFR2. TNFR1 activation may result in either cell proliferation or cell death. TNFR2 activates Nuclear Factor-kappaB (NF-kB) and c-Jun N-terminal kinase (JNK) which lead to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5111960f124f1dd938eaada54de703f
https://doi.org/10.18632/oncotarget.1492
https://doi.org/10.18632/oncotarget.1492
Autor:
Pedro S. Lazo, Patricia Ruperez, Pedro Zuazua-Villar, Alma L. Burlingame, Lucia Cabal-Hierro, Sofía Ramos, Miguel A. Prado, Noelia Artime, Pedro Casado, Eva del Valle
Publikováno v:
Journal of Proteomics. 71:592-600
Microtubule interfering agents (MIAs) are anti-tumor drugs that inhibit microtubule dynamics, while kinesin spindle protein (KSP) inhibitors are substances that block the formation of the bipolar spindle during mitosis. All these compounds cause G2/M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d9360514e481b9cc65f7f9fa32f5eb
https://doi.org/10.1016/j.jprot.2008.09.001
https://doi.org/10.1016/j.jprot.2008.09.001
Autor:
Lucia Cabal-Hierro, Noelia Artime, Pedro Zuazua-Villar, Eva del Valle, Carlos Martínez-Campa, Pedro S. Lazo, Pedro Casado, Sofía Ramos, Miguel A. Prado
Publikováno v:
PROTEOMICS. 7:3299-3304
Departamento de Bioquimica y Biologia Molecular, Instituto Universitario de Oncologiadel Principado de Asturias, Universidad de Oviedo, Oviedo, SpainPaclitaxel (Ptx) is an antitumoural drug that inhibits microtubule dynamics, causes G2/M arrestand in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8493ea2dd075b69ace306b3a89adaf8e
https://doi.org/10.1002/pmic.200700226
https://doi.org/10.1002/pmic.200700226
Autor:
Juan P. Rodrigo, Ignacio Álvarez, Pedro S. Lazo, María Victoria González, Luis A. García, Eliecer Coto, Sofía Ramos, Carlos Suárez
Publikováno v:
Oral Oncology. 38:357-363
The objective of this study is to describe the molecular alterations in carcinomas in one specific location of the head and neck, the hypopharynx. Thirty-seven hypopharyngeal squamous cell carcinomas were studied. The DNA from tumour and healthy tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232da5b927d988515c2550bb5eab3c52
https://doi.org/10.1016/s1368-8375(01)00071-9
https://doi.org/10.1016/s1368-8375(01)00071-9
Autor:
Juana García Pedrero, Masami Muramatsu, Beatriz Del Rio, Pedro S. Lazo, Carlos Martínez-Campa, Sofía Ramos
Publikováno v:
Molecular Endocrinology. 16:947-960
In the search for differences between ERalpha and ERbeta, we analyzed the interaction of both receptors with calmodulin (CaM) and demonstrated that ERalpha but not ERbeta directly interacts with CaM. Using transiently transfected HeLa cells, we exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2adbb3d460c776bd97f03c76960ab598
https://doi.org/10.1210/mend.16.5.0830
https://doi.org/10.1210/mend.16.5.0830
Autor:
Pedro S. Lazo, Lorea Ugarte, Noelia Artime, Miguel A. Prado, Lucia Cabal-Hierro, J. Iglesias, Montserrat Rodríguez
Publikováno v:
Cellular signalling. 26(12)
Tumor Necrosis Factor Receptor 2 (TNFR2) activates transcription factor κB (NF-κB) and c-Jun N-terminal kinase (JNK). Most of the biological activities triggered by TNFR2 depend on the recruitment of TNF Receptor-Associated Factor 2 (TRAF2) to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754216a81a4624f772ba31d7709b71a5
https://pubmed.ncbi.nlm.nih.gov/25152365
https://pubmed.ncbi.nlm.nih.gov/25152365
Publikováno v:
Genomics. 52:79-89
The mouse TNFR2 gene has been cloned, sequenced, and characterized as a gene spanning44 kb of the genome. By alignment of five genomic clones we have established that TNFR2 consists of 10 exons and 9 introns with exons ranging in size from 35 bp to 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e71143f3e3b6f9eee5339257ae5749
https://doi.org/10.1006/geno.1998.5407
https://doi.org/10.1006/geno.1998.5407
Autor:
Ignacio Álvarez, Pedro S. Lazo, Carlos Suárez Nieto, Sofia Ramos Gonzalez, Faustino Núñez Batalla, J. Pablo Rodrigo Tapia
Publikováno v:
American Journal of Otolaryngology. 18:375-381
Purpose: Increasingly, evidence has shown that human papillomavirus (HPV) plays a role in the induction of certain carcinomas. The presence of HPV sequences in 56 previously untreated oral and pharyngolaryngeal carcinomas was examined by the polymera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d53d8ba00bedee7ed5343661f33a7ef
https://doi.org/10.1016/s0196-0709(97)90056-9
https://doi.org/10.1016/s0196-0709(97)90056-9
Publikováno v:
European Journal of Cancer. 32:2004-2010
The activation of ERBB oncogenes has been described in various human tumours, including squamous cell carcinomas of the head and neck (SCCHN), and, in some of them, it has been correlated with a poor prognosis. Tissue samples from 59 patients with SC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76fa67ed49b26fd59a0359bc60d516b
https://doi.org/10.1016/0959-8049(96)00223-7
https://doi.org/10.1016/0959-8049(96)00223-7
Autor:
Pedro S. Lazo, Kazimierz Wrobel, Fernando Segade, Rodrigo Bravo, Estefanía Claudio, Sofía Ramos
Publikováno v:
Experimental Cell Research. 224:63-71
The murine fibrosarcoma cell line WEHI 164 is well known for its susceptibility to tumor necrosis factor (TNFalpha). We have studied the activation of the transcription factor NF-kappaB when WEHI 164 cells are challenged with TNFalpha. NF-kappaB is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96dc468d133aa56b484cd8224541597f
https://doi.org/10.1006/excr.1996.0111
https://doi.org/10.1006/excr.1996.0111