Immunomodulatory Response of Toll-like Receptor Ligand–Peptide Conjugates in Food Allergy

Autor: Javier Rojo, María José Torres, Javier Ramos-Soriano, Pedro Ramírez-López, Francisca Gómez, Cristobalina Mayorga, Jorge Losada Méndez, Francisca Palomares

Publikováno v: ACS Chemical Biology

Covalent conjugation of allergens to toll-like receptor (TLR) agonists appears to be a powerful strategy for the development of safety compounds for allergen-specific immunomodulatory response toward tolerance in allergy. In this work, we have synthe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b94747f782b3dfb1258bf02e0e0f127
http://europepmc.org/articles/PMC8609526

A Dynamic Kinetic C–P Cross–Coupling for the Asymmetric Synthesis of Axially Chiral P,N Ligands

Autor: Pedro Ramírez-López, Béla Fiser, José M. Lassaletta, Beatriz Estepa, Rosario Fernández, Abel Ros, Enrique Gómez-Bengoa

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS. Depósito de Investigación de la Universidad de Sevilla

The Pd-catalyzed enantioselective C-P cross-coupling between racemic, configurationally stable heterobiaryl triflates and trialkylsilyldiaryl(dialkyl)phosphines has been used for the synthesis of several families of enantiomerically enriched heterobi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8bd110af1714a55b895253a7c611c0c
https://doi.org/10.1021/acscatal.6b00784

The Reversible Nicholas Reaction in the Synthesis of Highly Symmetric Natural-Product-Based Macrocycles

Autor: Miguel A. Sierra, María C. de la Torre, Pedro Ramírez-López, María Asenjo

Publikováno v: European Journal of Organic Chemistry. 2015:1054-1067

Two different approaches to highly symmetric macrocycles by reversible Nicholas reactions have been developed. The first sequence uses a bis[Co2(CO)6] complex derived from a double propargylic alcohol supporting two natural product moieties. The reac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7884697c46aa03388fe4a9a2226d5fc3
https://doi.org/10.1002/ejoc.201403541

Red-emitting tetracoordinate organoboron chelates : synthesis, photophysical properties, and fluorescence microscopy

Autor: Daniel Collado, Vânia F. Pais, Pedro Ramírez-López, Uwe Pischel, Francisco Najera, José M. Lassaletta, Antonio Romero-Arenas, Rosario Fernández, Abel Ros, Ezequiel Perez-Inestrosa

Publikováno v: Arias Montano. Repositorio Institucional de la Universidad de Huelva
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
Digital.CSIC. Repositorio Institucional del CSIC

Seven tetra-coordinate organoboron fluorophores with hetero-biaryl N,O or N,N chelate ligands were prepared and photophysically characterized (in toluene). The electronic variation of the heteroaromatic moiety provided a means for the fine-tuning of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0303ebd6607e5c94cdada99b8fa991
http://hdl.handle.net/10272/14654

A Copper-Catalyzed Azide−Alkyne Cycloaddition Approach to the Synthesis of Bimetallic Chromium(0) (Fischer) Carbene Complexes

Autor: Pedro Ramírez-López, Miguel A. Sierra, Mar Gómez-Gallego, Luis Casarrubios, Beatriz Baeza

Publikováno v: Organometallics. 28:956-959

The Cu(I)-catalyzed 1,3-dipolar cycloaddition of bis-azides to alkynyl chromium(0) (Fischer) carbene complexes has been developed. The method is a new entry to the synthesis of highly functionalize...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d5326ec37db30369e56fba31e2a9097
https://doi.org/10.1021/om801171x