Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Pedro R. Urquilla"'
Autor:
Sherwyn Schwartz, Mark E. Williams, Carlos J. Arauz-Pacheco, Thomas B. Neff, Warren K. Bolton, Dongxia Li, Pedro R. Urquilla, Tyson Lee, K. Lea Sewell, Sharon G. Adler
Publikováno v:
Clinical Journal of the American Society of Nephrology. 5:1420-1428
Background and objectives: This report summarizes the first phase 1 trial treating patients with microalbuminuric diabetic kidney disease (DKD) using FG-3019, a human monoclonal antibody to connective tissue growth factor (CTGF). CTGF is critically i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890012093d4e3e3e81679e3adbdb7194
https://doi.org/10.2215/cjn.09321209
https://doi.org/10.2215/cjn.09321209
Autor:
Robert Z. Orlowski, Suzanne Trudel, Andre Goy, Melissa Alsina, Pedro R. Urquilla, Christopher J. Molineaux, Keith Stewart, Marcy Vallone, Tina M. Woo, Owen A. O'Connor
Publikováno v:
Blood. 108:2430-2430
INTRODUCTION: PR-171 is a novel, irreversible proteasome inhibitor under investigation for the treatment of hematological malignancies. In preclinical studies, PR-171 was well tolerated in rats and monkeys when given daily × 5 (QDx5), every two week
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc81f8f5ee8d60441acf0ff08e9242a0
https://doi.org/10.1182/blood.v108.11.2430.2430
https://doi.org/10.1182/blood.v108.11.2430.2430
Autor:
Pedro R. Urquilla
Publikováno v:
Journal of Vascular Research. 13:249-252
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f072a8147be091f8a254ec58958b7a6d
https://doi.org/10.1159/000158093
https://doi.org/10.1159/000158093
Publikováno v:
Journal of Vascular Research. 12:53-67
5-Hydroxytryptamine (5-HT), norepinephrine (NE), histamine (H) and potassium (K+) chloride induce dose-dependent changes in tension of the isolated middle cerebral artery of the goat. Vasopressin produces highly variable responses followed by tachyph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15686a1d193e71b4cdaa6619532c5f59
https://doi.org/10.1159/000158038
https://doi.org/10.1159/000158038
Autor:
Mark E. Wilson, Robert L. Robinson, Michael D. Taylor, David M. Smith, Pedro R. Urquilla, Michael A. Trush, Knox Van Dyke
Publikováno v:
Pharmacology. 15:377-391
The catecholamine and nucleotide content of chromaffin granules from bovine adrenal medulla was analyzed both qualitatively and quantitatively. Nucleotides were examined by separation on anion exchange high pressure liquid chromatography and ultravio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04cdf0ec1e54e00f06702f1cfa61bb98
https://doi.org/10.1159/000136714
https://doi.org/10.1159/000136714
Publikováno v:
Stroke. 5(4)
Tyramine induces dose-dependent changes in tension of the isolated middle cerebral artery of the goat. Cocaine, phentolamine and reserpine reduce the sensitivity of the tissue to tyramine by factors of 2.8, 3.7 and 3.7, respectively. The norepinephri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a975f56d3ba508fede6dbf9f66098c
https://pubmed.ncbi.nlm.nih.gov/4850443
https://pubmed.ncbi.nlm.nih.gov/4850443
Publikováno v:
European journal of pharmacology. 66(1)
Potassium ( 42 K) or chloride ( 36 Cl) efflux curves were determined in guinea-pig vas deferens from control, reserpine-treated animals (1 mg/kg/day i.p. for 5 days), and from animals whose vas deferens had been sympathetically denervated 1 week befo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70de50cd9494ec3968e17cd798b075c2
https://pubmed.ncbi.nlm.nih.gov/7408957
https://pubmed.ncbi.nlm.nih.gov/7408957
Publikováno v:
Journal of Pharmacy and Pharmacology. 30:189-190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992d72dfc91df980bdef9d781e19908d
https://doi.org/10.1111/j.2042-7158.1978.tb13197.x
https://doi.org/10.1111/j.2042-7158.1978.tb13197.x
Autor:
David Smith, Fred A. Simpson, Chang W. Rhee, Hang J. Yoon, Richard B. Knapp, Jeanne M. Rushin, Hak S. Lee, Thara Srichomkuan, Pedro R. Urquilla
Publikováno v:
Anesthesia & Analgesia. 58:189
The cardiovascular effects of benzquinamide were evaluated in anesthetized dogs. Intravenous benzquinamide, 0.5 to 5 mg/kg, caused tachycardia, elevated blood norepinephrine levels, frequent ventricular arrhythmias, and brief hypotension. Ganglionic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aebaeae17363475448ecadd22caea9b
https://doi.org/10.1213/00000539-197905000-00006
https://doi.org/10.1213/00000539-197905000-00006
Autor:
J. Morganroth, E. Neil Moore
The Symposium on New Drugs provides for an annual forum for academic investigators, research and development personnel from the pharmaceutical and related health care industries, and members of the Food and Drug Administration to discuss important cl
