Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Pedro R. Figueiredo"'
Publikováno v:
Journal of Medicinal Chemistry. 66:2761-2772
Autor:
Beatriz C. Almeida, Pedro R. Figueiredo, Daniel F.A.R. Dourado, Stephanie Paul, Andreia F. Sousa, Armando J.D. Silvestre, Derek J. Quinn, Thomas S. Moody, Alexandra T.P. Carvalho
Enzymatic synthesis of polymeric materials is a powerful approach to make these processes greener, more economical, and safer for scale-up. Herein, we characterized new variants of the hyperthermophilic carboxylesterase from the archaeon Archaeoglobu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be94758283c9d531827eb190b2f272a7
http://hdl.handle.net/10773/36075
http://hdl.handle.net/10773/36075
Autor:
Isaura Simões, Sónia F. G. Santos, Pedro R. Figueiredo, Beatriz C. Almeida, Alexandra T. P. Carvalho
Publikováno v:
The Journal of Physical Chemistry B. 125:4368-4374
The development of plant-based synthetic rennets is of high commercial interest, due to the current great consumer demand for animal product alternatives. A previously developed recombinant form of the aspartic protease cardosin B with a three-glycin
Autor:
Carlos B. P. Oliveira, Sérgio R. S. Veloso, Elisabete M. S. Castanheira, Pedro R. Figueiredo, Alexandra T. P. Carvalho, Loic Hilliou, Renato B. Pereira, David M. Pereira, José A. Martins, Paula M. T. Ferreira, Peter J. Jervis
Publikováno v:
Soft matter. 18(20)
Short peptides capped on the N-terminus with aromatic groups are often able to form supramolecular hydrogels—self-assembled networks of fibrils able to trap water molecules. Typically, these hydrogelators can form stiff gels at concentrations of 0.
Nucleic acid technologies with designed delivery systems have surged as one the most promising therapies of the future, due to their contribution in combating SARS-CoV-2 severe disease. Nevertheless, the emergence of new variants of concern still rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::496ff348f359aac36de0802d3895ddcf
https://doi.org/10.1101/2022.02.09.479755
https://doi.org/10.1101/2022.02.09.479755
Autor:
Alexandra T. P. Carvalho, Daniel F. A. R. Dourado, Armando J. D. Silvestre, Pedro R. Figueiredo, Andreia F. Sousa, Beatriz C. Almeida
Publikováno v:
ChemCatChem. 12:4845-4852
Increased hydrolysis of cocaine to nontoxic compounds is a promising way to prevent cocaine-induced toxicity. However, the short half-life of cocaine in the blood and the rapid conversion in the body to the hydrolysis-resistant metabolite benzoylecgo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29eb65b59561b057747ff753e6e7c772
https://doi.org/10.33774/chemrxiv-2021-t5939
https://doi.org/10.33774/chemrxiv-2021-t5939
Autor:
Juliana Garcia, Alexandra Carvalho, Ricardo Pires das Neves, Rui Malheiro, Daniela F. Rodrigues, Pedro R. Figueiredo, Antonio Bovolini, José Alberto Duarte, Vera Marisa Costa, Félix Carvalho
Publikováno v:
Food and Chemical Toxicology. 166:113198
Amanita phalloides is one of the most toxic mushrooms worldwide, being responsible for the majority of human fatal cases of mushroom intoxications. α-Amanitin, the most deleterious toxin of A. phalloides, inhibits RNA polymerase II (RNAP II), causin
Autor:
Alexandra T. P. Carvalho, Pedro R. Figueiredo, Kristala L. J. Prather, Beatriz C. Almeida, Jennifer A Kaczmarek
Publikováno v:
NAR Genomics and Bioinformatics
The development of new synthetic biology circuits for biotechnology and medicine requires deeper mechanistic insight into allosteric transcription factors (aTFs). Here we studied the aTF UxuR, a homodimer of two domains connected by a highly flexible
Publikováno v:
ACS Omega, Vol 4, Iss 4, Pp 6769-6774 (2019)
Accumulation of plastic waste is a major environmental problem. Enzymes, particularly esterases, play an important role in the biodegradation of polyesters. These enzymes are usually only active on...