Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Pedro Pesini"'
Autor:
Hyemin Jang, Ji Sun Kim, Hye Joo Lee, Chi-Hun Kim, Duk L. Na, Hee Jin Kim, José Antonio Allué, Leticia Sarasa, Sergio Castillo, Pedro Pesini, John Gallacher, Sang Won Seo, on behalf of DPUK
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2021)
Abstract Background We assessed the feasibility of plasma Aβ42/Aβ40 determined using a novel liquid chromatography-mass spectrometry method (LC-MS) as a useful biomarker of PET status in a Korean cohort from the DPUK Study. Methods A total of 580 p
Externí odkaz:
https://doaj.org/article/d74c332c41954d569a82cfd39407f8ed
Autor:
Virginia Pérez-Grijalba, Javier Arbizu, Judith Romero, Elena Prieto, Pedro Pesini, Leticia Sarasa, Fernando Guillen, Inmaculada Monleón, Itziar San-José, Pablo Martínez-Lage, Josep Munuera, Isabel Hernández, Mar Buendía, Oscar Sotolongo-Grau, Montserrat Alegret, Agustín Ruiz, Lluis Tárraga, Mercè Boada, Manuel Sarasa, The AB255 Study Group
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-9 (2019)
Abstract Background To facilitate population screening and clinical trials of disease-modifying therapies for Alzheimer’s disease, supportive biomarker information is necessary. This study was aimed to investigate the association of plasma amyloid-
Externí odkaz:
https://doaj.org/article/8ea557f727a645db9b4c9c8e9f242844
Autor:
Shannon L. Risacher, Noelia Fandos, Judith Romero, Ian Sherriff, Pedro Pesini, Andrew J. Saykin, Liana G. Apostolova
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 510-519 (2019)
Abstract Introduction We investigated the relationship of plasma amyloid beta (Aβ) with cerebral deposition of Aβ and tau on positron emission tomography (PET). Methods Forty‐four participants (18 cognitively normal older adults [CN], 10 mild cog
Externí odkaz:
https://doaj.org/article/6d69ae07093b4675b4f5490eb20a0ec3
Autor:
Josef Pannee, Leslie M. Shaw, Magdalena Korecka, Teresa Waligorska, Charlotte E. Teunissen, Erik Stoops, Hugo M. J. Vanderstichele, Kimberley Mauroo, Inge M. W. Verberk, Ashvini Keshavan, Pedro Pesini, Leticia Sarasa, Maria Pascual‐Lucas, Noelia Fandos, José‐Antonio Allué, Erik Portelius, Ulf Andreasson, Ritsuko Yoda, Akinori Nakamura, Naoki Kaneko, Shieh‐Yueh Yang, Huei‐Chun Liu, Stefan Palme, Tobias Bittner, Kwasi G. Mawuenyega, Vitaliy Ovod, James Bollinger, Randall J. Bateman, Yan Li, Jeffrey L. Dage, Erik Stomrud, Oskar Hansson, Jonathan M. Schott, Kaj Blennow, Henrik Zetterberg
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Blood‐based assays to measure brain amyloid beta (Aβ) deposition are an attractive alternative to the cerebrospinal fluid (CSF)–based assays currently used in clinical settings. In this study, we examined different blood‐
Externí odkaz:
https://doaj.org/article/07cf8801f7b140a6a12154efbdfca507
Autor:
Ana-María Lacosta, María Pascual-Lucas, Pedro Pesini, Diego Casabona, Virginia Pérez-Grijalba, Iván Marcos-Campos, Leticia Sarasa, Jesus Canudas, Hassnae Badi, Inmaculada Monleón, Itziar San-José, Josep Munuera, Octavio Rodríguez-Gómez, Carla Abdelnour, Asunción Lafuente, Mar Buendía, Mercè Boada, Lluis Tárraga, Agustín Ruiz, Manuel Sarasa
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-13 (2018)
Abstract Background Immunotherapy targeting the amyloid-β (Aβ) peptide is a promising strategy for the treatment of Alzheimer’s disease (AD); however, none of the active or passive vaccines tested have been demonstrated to be effective to date. W
Externí odkaz:
https://doaj.org/article/1030c599a5ae4b4d8f002a265d9af497
Autor:
Noelia Fandos, Virginia Pérez‐Grijalba, Pedro Pesini, Salvador Olmos, Matías Bossa, Victor L. Villemagne, James Doecke, Christopher Fowler, Colin L. Masters, Manuel Sarasa, AIBL Research Group
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 8, Iss 1, Pp 179-187 (2017)
Abstract Introduction Plasma amyloid β (Aβ) peptides have been previously studied as candidate biomarkers to increase recruitment efficiency in secondary prevention clinical trials for Alzheimer's disease. Methods Free and total Aβ42/40 plasma rat
Externí odkaz:
https://doaj.org/article/688464d11df04c72be99820729a02c57
Autor:
Gorka Fernández-Eulate, Ainhoa Alberro, Maider Muñoz-Culla, Miren Zulaica, Mónica Zufiría, Myriam Barandiarán, Igone Etxeberria, José Javier Yanguas, Maria Mercedes Gallardo, Nora Soberón, Ana María Lacosta, Virginia Pérez-Grijalba, Jesús Canudas, Noelia Fandos, Pedro Pesini, Manuel Sarasa, Begoña Indakoetxea, Fermin Moreno, Itziar Vergara, David Otaegui, Maria Blasco, Adolfo López de Munain
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Many factors may converge in healthy aging in the oldest old, but their association and predictive power on healthy or functionally impaired aging has yet to be demonstrated. By detecting healthy aging and in turn, poor aging, we could take action to
Externí odkaz:
https://doaj.org/article/5c9f9dd3f9d946de9baecb040aaab476
Autor:
Agustín Ruiz, Pedro Pesini, Ana Espinosa, Virginia Pérez-Grijalba, Sergi Valero, Oscar Sotolongo-Grau, Montserrat Alegret, Inmaculada Monleón, Asunción Lafuente, Mar Buendía, Marta Ibarria, Susana Ruiz, Isabel Hernández, Itziar San José, Lluís Tárraga, Mercè Boada, Manuel Sarasa
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/6111a5c9149a442c8ec088d33758a781
Autor:
Jesús Canudas, Daniel Insua, Leticia Sarasa, Ángela González-Martínez, María Luisa Suárez, Germán Santamarina, Pedro Pesini, Manuel Sarasa
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2014 (2014)
Neprilysin (NEP) is the principal amyloid β (Aβ) degrading peptidase; this activity may protect against Alzheimer’s disease (AD), the most important age-related neurodegenerative process. The aim of this work was to analyze NEP mRNA expression in
Externí odkaz:
https://doaj.org/article/bd700db84a974f28964f29c918326819
Autor:
Agustín Ruiz, Pedro Pesini, Ana Espinosa, Virginia Pérez-Grijalba, Sergi Valero, Oscar Sotolongo-Grau, Montserrat Alegret, Inmaculada Monleón, Asunción Lafuente, Mar Buendía, Marta Ibarria, Susana Ruiz, Isabel Hernández, Itziar San José, Lluís Tárraga, Mercè Boada, Manuel Sarasa
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81334 (2013)
Plasma amyloid beta (Aβ) levels are being investigated as potential biomarkers for Alzheimer's disease. In AB128 cross-sectional study, a number of medical relevant correlates of blood Aβ40 or Aβ42 were analyzed in 140 subjects (51 Alzheimer's dis
Externí odkaz:
https://doaj.org/article/1144d95a6c12445f803e453f2c87a54d