Toll-like receptor 4 promotes autonomic dysfunction, inflammation and microglia activation in the hypothalamic paraventricular nucleus: role of endoplasmic reticulum stress.

Autor: Gustavo S Masson, Anand R Nair, Rahul B Dange, Pedro Paulo Silva-Soares, Lisete C Michelini, Joseph Francis

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0122850 (2015)

Toll-like receptor 4 (TLR4) signaling induces tissue pro-inflammatory cytokine release and endoplasmic reticulum (ER) stress. We examined the role of TLR4 in autonomic dysfunction and the contribution of ER stress.Our study included animals divided i

Externí odkaz: https://doaj.org/article/dfd9302cb75a4048b630d95d18f059c1

Toll-Like Receptor 4 Promotes Autonomic Dysfunction, Inflammation and Microglia Activation in the Hypothalamic Paraventricular Nucleus: Role of Endoplasmic Reticulum Stress

Autor: Rahul B. Dange, Gustavo S. Masson, Lisete Compagno Michelini, Pedro Paulo Silva-Soares, Joseph Francis, Anand R. Nair

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0122850 (2015)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS ONE

Background & Purpose Toll-like receptor 4 (TLR4) signaling induces tissue pro-inflammatory cytokine release and endoplasmic reticulum (ER) stress. We examined the role of TLR4 in autonomic dysfunction and the contribution of ER stress. Experimental a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a208561b9e2d4883133d1d54950e1ac
https://doi.org/10.1371/journal.pone.0122850