Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Pedro Miguel Salcedo Gomez"'
Autor:
Masayuki Amano, Akira Mizuno, Sofiya Yashchuk, Pedro Miguel Salcedo Gomez, Arun K. Ghosh, Debananda Das, Hiroaki Mitsuya
Publikováno v:
Antimicrobial Agents and Chemotherapy. 57:6110-6121
We designed, synthesized, and identified two novel nonpeptidic human immunodeficiency virus type 1 (HIV-1) protease inhibitors (PIs), GRL-04810 and GRL-05010, containing the structure-based designed privileged cyclic ether-derived nonpeptide P2 ligan
Autor:
Hiroaki Mitsuya, Akira Mizuno, Pedro Miguel Salcedo Gomez, Yuan-Fang Wang, Masayuki Amano, Sofiya Yashchuk, Irene T. Weber, Arun K. Ghosh, Johnson Agniswamy, Manabu Aoki, Nilanjana Chakraborty
The structure-based design, synthesis, biological evaluation, and X-ray structural studies of fluorine-containing HIV-1 protease inhibitors are described. The synthesis of both enantiomers of the gem-difluoro-bis-THF ligands was carried out in a ster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::149dcb0e20f249002cd5d0c94a922989
https://europepmc.org/articles/PMC4419590/
https://europepmc.org/articles/PMC4419590/