Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Pedro M. P. Gois"'
Autor:
Ana S. André, Joana N. R. Dias, Sandra Aguiar, Sara Nogueira, Pedro Bule, Joana Inês Carvalho, João P. M. António, Marco Cavaco, Vera Neves, Soraia Oliveira, Gonçalo Vicente, Belmira Carrapiço, Berta São Braz, Barbara Rütgen, Lurdes Gano, João D. G. Correia, Miguel Castanho, Joao Goncalves, Pedro M. P. Gois, Solange Gil, Luís Tavares, Frederico Aires-da-Silva
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Antibody–drug conjugates (ADCs) are among the fastest-growing classes of therapeutics in oncology. Although ADCs are in the spotlight, they still present significant engineering challenges. Therefore, there is an urgent need to develop mor
Externí odkaz:
https://doaj.org/article/f9c1a085d74e4cbdaf2217e2c95385f7
Publikováno v:
ACS Omega, Vol 3, Iss 7, Pp 7418-7423 (2018)
Externí odkaz:
https://doaj.org/article/b844fe88fcc54db08acace9c55b8fa1d
Autor:
Maria V. Pinto, Fábio M. F. Santos, Catarina Barros, Ana Rita Ribeiro, Uwe Pischel, Pedro M. P. Gois, Adelaide Fernandes
Publikováno v:
Cells, Vol 10, Iss 11, p 3163 (2021)
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that is characterized by the presence of demyelinated regions with accumulated myelin lipid debris. Importantly, to allow effective remyelination, such debris must be cl
Externí odkaz:
https://doaj.org/article/26e2372176704b5aa39e29b1b4aaad9e
Autor:
Raquel R. Lopes, Catarina S. Tomé, Roberto Russo, Roberta Paterna, João Leandro, Nuno R. Candeias, Lídia M. D. Gonçalves, Miguel Teixeira, Pedro M. F. Sousa, Rita C. Guedes, João B. Vicente, Pedro M. P. Gois, Paula Leandro
Publikováno v:
Biomolecules, Vol 11, Iss 3, p 462 (2021)
Phenylketonuria (PKU) is a genetic disease caused by deficient activity of human phenylalanine hydroxylase (hPAH) that, when untreated, can lead to severe psychomotor impairment. Protein misfolding is recognized as the main underlying pathogenic mech
Externí odkaz:
https://doaj.org/article/930e60cb46ef4088b66394b0dbb9f7c4
Autor:
Diogo L. Poeira, Ana Cláudia R. Negrão, Hélio Faustino, Jaime A. S. Coelho, Clara S. B. Gomes, Pedro M. P. Gois, M. Manuel B. Marques
Publikováno v:
Organic Letters. 24:776-781
A new family of hypervalent iodine reagents containing transferable primary amine groups is described. Benziodoxolone-based reagents were synthesized on the gram-scale through operationally simple reactions in up to quantitative yields. These bench-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a6b9becdc73026217d707e8dd2effa
https://doi.org/10.1021/acs.orglett.1c04312
https://doi.org/10.1021/acs.orglett.1c04312
Autor:
João P. M. António, Joana Inês Carvalho, Ana S. André, Joana N. R. Dias, Sandra I. Aguiar, Hélio Faustino, Ricardo M. R. M. Lopes, Luis F. Veiros, Gonçalo J. L. Bernardes, Frederico A. Silva, Pedro M. P. Gois
Publikováno v:
Angewandte Chemie. 133:26118-26125
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::477943df774d448bd8b49e7a13edbc83
https://doi.org/10.1002/ange.202109835
https://doi.org/10.1002/ange.202109835
Autor:
Maria J. S. A. Silva, Robin Vinck, Youchao Wang, Bruno Saubaméa, Mickaël Tharaud, Elena Dominguez‐Jurado, Johannes Karges, Pedro M. P. Gois, Gilles Gasser
Publikováno v:
ChemBioChem
ChemBioChem, 2022, ⟨10.1002/cbic.202200647⟩
ChemBioChem, 2022, ⟨10.1002/cbic.202200647⟩
International audience; There is an increasing number of novel Ru(II) polypyridyl complexes successfully applied as photosensitizers (PSs) for photodynamic therapy (PDT). Despite recent advances on optimized PSs with refined photophysical properties,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5dbf54943f70db49fae4d1ad048358
https://hal.archives-ouvertes.fr/hal-03892332
https://hal.archives-ouvertes.fr/hal-03892332
Autor:
Maria J. S. A. Silva, Rafaela A. N. Cavadas, Hélio Faustino, Luís F. Veiros, Pedro M. P. Gois
Publikováno v:
Chemistry – A European Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ab1be82efb71e651b00d438576544e0
https://doi.org/10.1002/chem.202203566
https://doi.org/10.1002/chem.202203566
Autor:
Maria J. S. A. Silva, Rafaela A. N. Cavadas, Hélio Faustino, Luís F. Veiros, Pedro M. P. Gois
Publikováno v:
Chemistry – A European Journal. 28
N-terminal Cys modification has been intensively studied to produce homogeneous bioconjugates essentially through two modes of reaction: reversible modification with the equilibrium shifted towards the formation of the desired conjugate or stable and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c9ebb96d62db041299b2bdf47de650
https://doi.org/10.1002/chem.202202377
https://doi.org/10.1002/chem.202202377
Autor:
Cláudia F. Afonso, Marta C. Marques, João P. M. António, Carlos Cordeiro, Pedro M. P. Gois, Pedro M. S. D. Cal, Gonçalo J. L. Bernardes
Publikováno v:
Angewandte Chemie International Edition. 61
Post-translational modifications of histones are essential in the regulation of chromatin structure and function. Among these modifications, lysine acetylation is one of the most established. Earlier studies relied on the use of chromatin containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa51552209387c406ed7a09438db830
https://doi.org/10.1002/anie.202208543
https://doi.org/10.1002/anie.202208543