Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Pedro M. Faustmann"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Externí odkaz:
https://doaj.org/article/f3870b6d1fe4469baada25ee4dfcbc14
Autor:
Fatme Seval Ismail, Pedro M. Faustmann
Publikováno v:
Epilepsia Open, Vol 8, Iss 2, Pp 692-701 (2023)
Abstract The γ‐aminobutyric acid (GABA) is the main inhibitory transmitter in the central nervous system and GABA receptors mediate the inhibitory synaptic transmission. GABA binding to neuronal GABAAR leads to a rapid hyperpolarization and a high
Externí odkaz:
https://doaj.org/article/1393d06a8e324ed1a1706f1ddcda1e97
Autor:
Fatme Seval Ismail, Pedro M. Faustmann, Marie-Luise Kümmel, Eckart Förster, Timo Jendrik Faustmann, Franco Corvace
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Implications of glia in the pathophysiology of epilepsy raise the question of how these cells besides neurons are responsive to antiseizure medications (ASMs). Understanding ASM effects on glia and glia-mediated inflammation may help to explore astro
Externí odkaz:
https://doaj.org/article/9ad29a7e883a43809c6a77e0e480d09d
Autor:
Fatme Seval Ismail, Timo Jendrik Faustmann, Franco Corvace, Anamariya Tsvetanova, Zahra Moinfar, Pedro M. Faustmann
Publikováno v:
BMC Neuroscience, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background Hepatic encephalopathy (HE) is a neurological complication resulting from acute or chronic liver disease. Hyperammonemia leading to astrocyte swelling and cerebral edema in combination with neuroinflammation including microglia ac
Externí odkaz:
https://doaj.org/article/57a6598a1f4642428372b27efd3393ac
Autor:
Timo Jendrik Faustmann, Marisa Wawrzyniak, Pedro M. Faustmann, Franco Corvace, Fatme Seval Ismail
Publikováno v:
Brain Sciences, Vol 13, Iss 3, p 493 (2023)
Depression may occur in patients with multiple sclerosis, especially during interferon-β (IFN-β) treatment, and therapy with antidepressants may be necessary. Interactions of IFN-β with antidepressants concerning glia-mediated inflammation have no
Externí odkaz:
https://doaj.org/article/f5667e4e041f447bb4263d6355525d57
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Astrocytes and microglia are the main cell population besides neurons in the central nervous system (CNS). Astrocytes support the neuronal network via maintenance of transmitter and ion homeostasis. They are part of the tripartite synapse, composed o
Externí odkaz:
https://doaj.org/article/310b93ec413a41b0ab08f80113fa2684
Autor:
Franco Corvace, Timo Jendrik Faustmann, Sandra Heckers, Pedro M. Faustmann, Fatme Seval Ismail
Publikováno v:
Pharmacology. 108:188-198
Introduction: Multiple sclerosis (MS) is the most common chronic inflammatory, demyelinating disease of the central nervous system. Dimethyl fumarate (DMF) and monomethyl fumarate (MMF) belong to the disease-modifying drugs in treatment of MS. There
Autor:
Fatme Seval Ismail, Pedro M. Faustmann, Eckart Förster, Franco Corvace, Timo Jendrik Faustmann
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology.
Due to the role of astrocytes and microglia in the pathophysiology of epilepsy and limited studies of antiseizure medication (ASM) effects on glial cells, we studied tiagabine (TGB) and zonisamide (ZNS) in an astrocyte-microglia co-culture model of i
Publikováno v:
Behavioural Neurology, Vol 14, Iss 1-2, Pp 39-45 (2003)
Cognitive and emotional capabilities were evaluated in 73 female patients with stable relapsing-remitting definite, and/or laboratory-supported multiple sclerosis (MS) and were compared with 32 matched healthy controls. Patients were categorized acco
Externí odkaz:
https://doaj.org/article/3a881db4539240328c633d4fe9568beb
Publikováno v:
The international journal of neuropsychopharmacology. 25(3)
Background Astrocytes and microglia are involved in the pathophysiology of epilepsy and bipolar disorder with a link to inflammation. We aimed to investigate the effects of the antiepileptic and mood-stabilizing drugs lamotrigine (LTG) and topiramate