Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Pedro Lax"'
Autor:
María José Ruiz-Pastor, Xavier Sánchez-Sáez, Oksana Kutsyr, Henar Albertos-Arranz, Carla Sánchez-Castillo, Isabel Ortuño-Lizarán, Natalia Martínez-Gil, Lorena Vidal-Gil, Lucía Méndez, Manuel Sánchez-Martín, Victoria Maneu, Pedro Lax, Nicolás Cuenca
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-17 (2023)
Abstract Central areolar choroidal dystrophy is an inherited disorder characterized by progressive choriocapillaris atrophy and retinal degeneration and is usually associated with mutations in the PRPH2 gene. We aimed to generate and characterize a m
Externí odkaz:
https://doaj.org/article/e0e59e4df12f4f508050012bf7b865b6
Autor:
Xavier Sánchez-Sáez, Isabel Ortuño-Lizarán, Carla Sánchez-Castillo, Pedro Lax, Nicolás Cuenca
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-16 (2023)
Abstract Background The main clinical symptoms characteristic of Parkinson’s disease (PD) are bradykinesia, tremor, and other motor deficits. However, non-motor symptoms, such as visual disturbances, can be identified at early stages of the disease
Externí odkaz:
https://doaj.org/article/00736fbb7bb444c692ce47c80c3b6da4
Autor:
Henar Albertos-Arranz, Natalia Martínez-Gil, Xavier Sánchez-Sáez, Agustina Noailles, Clara Monferrer Adsuara, Lidia Remolí Sargues, Juan J. Pérez-Santonja, Pedro Lax, Ramón Calvo Andrés, Nicolás Cuenca
Publikováno v:
Eye and Vision, Vol 10, Iss 1, Pp 1-18 (2023)
Abstract Background Different ocular alterations have been described in patients with coronavirus disease 2019 (COVID-19). Our aim was to determine whether COVID-19 affected retinal cells and establish correlations with clinical parameters. Methods R
Externí odkaz:
https://doaj.org/article/aded30296c584f4e878c1a88e2cf8610
Autor:
Natalia Martínez-Gil, Oksana Kutsyr, Laura Fernández-Sánchez, Xavier Sánchez-Sáez, Henar Albertos-Arranz, Carla Sánchez-Castillo, Lorena Vidal-Gil, Nicolás Cuenca, Pedro Lax, Victoria Maneu
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16068 (2023)
Ischemia is the main cause of cell death in retinal diseases such as vascular occlusions, diabetic retinopathy, glaucoma, or retinopathy of prematurity. Although excitotoxicity is considered the primary mechanism of cell death during an ischemic even
Externí odkaz:
https://doaj.org/article/0e5b7b978401425ebc2e9aff31acb68d
Autor:
Natalia Martínez-Gil, Victoria Maneu, Oksana Kutsyr, Laura Fernández-Sánchez, Xavier Sánchez-Sáez, Carla Sánchez-Castillo, Laura Campello, Pedro Lax, Isabel Pinilla, Nicolás Cuenca
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
Multiple gene mutations have been associated with inherited retinal dystrophies (IRDs). Despite the spectrum of phenotypes caused by the distinct mutations, IRDs display common physiopathology features. Cell death is accompanied by inflammation and o
Externí odkaz:
https://doaj.org/article/e4a407effc654617ac0f4079c932c0a3
Autor:
Xavier Sánchez‑Sáez, Isabel Ortuño‑Lizarán, Carla Sánchez‑Castillo, Pedro Lax, Nicolás Cuenca
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/89d1fa55fcc2406bb915a514d1ff20e2
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 149, Iss , Pp 112911- (2022)
This review focuses on retina degeneration occurring during glaucoma, age-related macular degeneration (AMD), diabetic retinopathy (DR), and retinitis pigmentosa (RP), and on the potential therapeutic use of triads of repositioned medicines, addresse
Externí odkaz:
https://doaj.org/article/a7ec29209751473c88b1395732b87340
Autor:
Oksana Kutsyr, Lucía Maestre-Carballa, Mónica Lluesma-Gomez, Manuel Martinez-Garcia, Nicolás Cuenca, Pedro Lax
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The gut microbiome is known to influence the pathogenesis and progression of neurodegenerative diseases. However, there has been relatively little focus upon the implications of the gut microbiome in retinal diseases such as retinitis pigmen
Externí odkaz:
https://doaj.org/article/2ff93c3df9104dfe88e4c04a2a2a206d
Autor:
Laura Fernández-Sánchez, Henar Albertos-Arranz, Isabel Ortuño-Lizarán, Pedro Lax, Nicolás Cuenca
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
PurposeRetinitis pigmentosa is primarily characterized by a massive photoreceptor loss. But a global retinal remodeling occurs in later stages of the disease. At that phase, glial cells and retinal vasculature are also strongly affected. The main aim
Externí odkaz:
https://doaj.org/article/8feea8d9e0a8409ebe959f40711b9e14
Autor:
Laura Campello, Oksana Kutsyr, Agustina Noailles, Patrycja Michalska, Laura Fernández-Sánchez, Natalia Martínez-Gil, Isabel Ortuño-Lizarán, Xavier Sánchez-Sáez, Emilio de Juan, Pedro Lax, Rafael León, Antonio G. García, Nicolás Cuenca, Victoria Maneu
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 1, Pp 142-159 (2020)
Externí odkaz:
https://doaj.org/article/fd1c141c1f6741f0bb2aba5c80669253