Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Pedro L Martinez-Espinosa"'
Autor:
Pedro L Martinez-Espinosa, Jianping Wu, Chengtao Yang, Vivian Gonzalez-Perez, Huifang Zhou, Hongwu Liang, Xiao-Ming Xia, Christopher J Lingle
Publikováno v:
eLife, Vol 4 (2015)
Two mammalian genes, Kcnt1 and Kcnt2, encode pore-forming subunits of Na+-dependent K+ (KNa) channels. Progress in understanding KNa channels has been hampered by the absence of specific tools and methods for rigorous KNa identification in native cel
Externí odkaz:
https://doaj.org/article/3e7131681543466e9bccd504328f46df
Publikováno v:
The Journal of General Physiology
Martinez-Espinosa et al. show that FGF14 and the voltage-dependent Na+ channel Nav1.3 are the main regulators of rapidly inactivating currents and Nav channel availability in mouse adrenal chromaffin cells. Their results uncover a role for FGF14 in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273b4c101367f04e9e63711a2a96b40d
http://europepmc.org/articles/PMC8020717
http://europepmc.org/articles/PMC8020717
Publikováno v:
The Journal of General Physiology
Martinez-Espinosa et al. show that fast and slow recovery of voltage-dependent Na+ (Nav) channels in rat adrenal chromaffin cells depends on two independent inactivation pathways. Competition between these pathways regulates changes in Nav channel av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d168013a1a9f3e0d1a7fcb95d2f6a78
http://europepmc.org/articles/PMC7927663
http://europepmc.org/articles/PMC7927663
Voltage-dependent sodium (Nav) current in adrenal chromaffin cells (CCs) is rapidly inactivating and TTX-sensitive. The fractional availability of CC Nav current has been implicated in regulation of action potential (AP) frequency and the occurrence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dc30ceb9334189ba73a38a6933645de
https://doi.org/10.1101/2020.10.31.363341
https://doi.org/10.1101/2020.10.31.363341
Adrenal chromaffin cells (CCs) in rodents express a rapidly inactivating, TTX-sensitive sodium current. The current has generally been attributed to Nav1.7, although a possible role for Nav1.3 has also been suggested. Nav channels in rat CCs rapidly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47f842924e3e57821d6e8e99c0335ce9
https://doi.org/10.1101/2020.10.31.363416
https://doi.org/10.1101/2020.10.31.363416
Autor:
Xiao Ming Xia, Monica Sala-Rabanal, Pedro L. Martinez-Espinosa, Nikhil Bharadwaj, Jenny K. Gustafsson, Vivian Gonzalez-Perez, Albert C. Chen, Hongzhen Hu, Christopher J. Lingle, Matthew A. Ciorba, David M. Alvarado
Publikováno v:
Proc Natl Acad Sci U S A
Goblet cells (GCs) are specialized cells of the intestinal epithelium contributing critically to mucosal homeostasis. One of the functions of GCs is to produce and secrete MUC2, the mucin that forms the scaffold of the intestinal mucus layer coating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b162ec5885208bbd51ec8b4eaeb23bb
https://doi.org/10.1101/2020.10.23.341396
https://doi.org/10.1101/2020.10.23.341396
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 470:39-52
Adrenal chromaffin cells (CCs) are the main source of circulating catecholamines (CAs) that regulate the body response to stress. Release of CAs is controlled neurogenically by the activity of preganglionic sympathetic neurons through trains of actio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9092121a8afef76a1458a11bd589b4e7
https://doi.org/10.1007/s00424-017-2048-1
https://doi.org/10.1007/s00424-017-2048-1
Autor:
Sonja J. Pyott, Aizhen Yang-Hood, Mark A. Rutherford, Pedro L. Martinez-Espinosa, Christopher J. Lingle, Yu Zhou, Luis E. Boero, Shelby Payne, Maolei Xiao, Xiao-Ming Xia, Dora Persic, Babak V-Ghaffari
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 116(37), 18397-18403. NATL ACAD SCIENCES
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The perception of sound relies on sensory hair cells in the cochlea that convert the mechanical energy of sound into release of glutamate onto postsynaptic auditory nerve fibers. The hair cell receptor potential regulates the strength of synaptic tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c896841e188e56bb6a9bfb26e85e71
https://europepmc.org/articles/PMC6744894/
https://europepmc.org/articles/PMC6744894/
Publikováno v:
Pflugers Archiv : European journal of physiology. 470(1)
Adrenal chromaffin cells (CCs) are the main source of circulating catecholamines (CAs) that regulate the body response to stress. Release of CAs is controlled neurogenically by the activity of preganglionic sympathetic neurons through trains of actio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::581111dcd19df6086ad2a68b6efa8dca
https://pubmed.ncbi.nlm.nih.gov/28776261
https://pubmed.ncbi.nlm.nih.gov/28776261
Autor:
Vivian Gonzalez-Perez, Xiao-Ming Xia, Chengtao Yang, Christopher J. Lingle, Pedro L. Martinez-Espinosa
Publikováno v:
The Journal of General Physiology
Chromaffin cells from mice lacking the BK β2 subunit show decreased action potential firing during current injection but an increase in spontaneous burst firing.
Rat and mouse adrenal medullary chromaffin cells (CCs) express an inactivating BK
Rat and mouse adrenal medullary chromaffin cells (CCs) express an inactivating BK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276c98ef62a7bac95d9091c9af9491ae
https://doi.org/10.1085/jgp.201411253
https://doi.org/10.1085/jgp.201411253