Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Pedro H.R. de A. Azevedo"'
Autor:
Thalita G. Barros, Luiz A.P. Flores-Junior, Luiza R.S. Dias, Suraby O. Albuquerque, Wagner B. Dias, Hector F. Loponte, Estela M.F. Muri, Adriane R. Todeschini, Eldio Gonçalves dos Santos, Pedro H.R. de A. Azevedo, Sergio Pinheiro, Camilo Henrique da Silva Lima
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 154
The vital enzyme O-linked β-N-acetylglucosamine transferase (OGT) catalyzes the O-GlcNAcylation of intracellular proteins coupling the metabolic status to cellular signaling and transcription pathways. Aberrant levels of O-GlcNAc and OGT have been l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f66e30097ae364ada6794e40adf5cf
https://pubmed.ncbi.nlm.nih.gov/32801002
https://pubmed.ncbi.nlm.nih.gov/32801002
Autor:
Lucas Villas Bôas Hoelz, Marcelo B. Zani, Lucas R. de Souza, Luiza R.S. Dias, Sergio Pinheiro, Silvia G. Passos, Bruna C. Zorzanelli, Pedro H.R. de A. Azevedo, Luciano Puzer, Estela M.F. Muri
Publikováno v:
European Journal of Medicinal Chemistry. 112:39-47
Human kallikrein 5 (KLK5) is a potential target for the treatment of skin inflammation and cancer. A new series of statine based peptidomimetic compounds were designed and synthesized through simple and efficient reactions. Some KLK5 inhibitors (2a-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6abb669a29bd6ae72c32310f6f5760
https://doi.org/10.1016/j.ejmech.2016.01.060
https://doi.org/10.1016/j.ejmech.2016.01.060
Autor:
Gustavo Tavares Ventura, Pedro H.R. de A. Azevedo, Thalita G. Barros, Aline C. Portela, Luiza R.S. Dias, Ronaldo Mohana-Borges, Sergio Pinheiro, Estela M.F. Muri, Anna Sophia C.L. Dantas, Camilo Henrique da Silva Lima
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(16)
Hepatitis C infection is a cause of chronic liver diseases such as cirrhosis and carcinoma. The current therapy for hepatitis C has limited efficacy and low tolerance. The HCV encodes a serine protease which is critical for viral replication, and few
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4a4ecb7e27166d8c41a1713e547b77
https://pubmed.ncbi.nlm.nih.gov/28729054
https://pubmed.ncbi.nlm.nih.gov/28729054
Autor:
Luiza R.S. Dias, Ronaldo Mohana-Borges, Amilcar Tanuri, Pedro H.R. de A. Azevedo, Gustavo Tavares Ventura, Alessandra Mendonça Teles de Souza, Anne Miranda Capaccia, Estela M.F. Muri, Bárbara Abrahim-Vieira, Emmerson Corrêa Brasil Da Costa, Sergio Pinheiro, Aline C. Portela, Carlos Rangel Rodrigues
Publikováno v:
Medicinal Chemistry Research. 23:5305-5320
Hepatitis C viral infection is a cause of chronic liver disease, and current therapies are only effective in 50 % of patients. Serine proteases, which are present in both hepatitis C virus (HCV) and the dengue virus, are the most studied class of pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50c106032a1a5791b085aad30470061c
https://doi.org/10.1007/s00044-014-1058-1
https://doi.org/10.1007/s00044-014-1058-1