Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Pedro H. V. Saavedra"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Tissue-resident macrophages exist in unique environments, or niches, that inform their identity and function. There is an emerging body of literature suggesting that the qualities of this environment, such as the types of cells and debris they eat, t
Externí odkaz:
https://doaj.org/article/0f34bad425d641bbaba7c00a5dd362e5
Autor:
Pedro H. V. Saavedra, Linyan Huang, Farzaneh Ghazavi, Stephanie Kourula, Tom Vanden Berghe, Nozomi Takahashi, Peter Vandenabeele, Mohamed Lamkanfi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
The enterotoxins TcdA and TcdB induce cytotoxicity of epithelial cells during Clostridium difficile infection. Here the authors show that bacterial induced epithelial cell death occurs via activation of caspases 3 and 7, resulting in apoptotic cell d
Externí odkaz:
https://doaj.org/article/708354e64dcb42588aa6882947904dbf
Cryptococcus neoformans Secretes Small Molecules That Inhibit IL-1β Inflammasome-Dependent Secretion
Autor:
Pedro Henrique Bürgel, Clara Luna Marina, Pedro H. V. Saavedra, Patrícia Albuquerque, Stephan Alberto Machado de Oliveira, Paulo Henrique de Holanda Veloso Janior, Raffael Araújo de Castro, Heino M. Heyman, Carolina Coelho, Radames J. B. Cordero, Arturo Casadevall, Joshua D. Nosanchuk, Ernesto S. Nakayasu, Robin C. May, Aldo Henrique Tavares, Anamelia Lorenzetti Bocca
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
Cryptococcus neoformans is an encapsulated yeast that causes disease mainly in immunosuppressed hosts. It is considered a facultative intracellular pathogen because of its capacity to survive and replicate inside phagocytes, especially macrophages. T
Externí odkaz:
https://doaj.org/article/297189d1324a485a8efaf9a6a63736d5
Autor:
Pedro H. V. Saavedra, Alissa Trzeciak, Zhaoquan Wang, Waleska Saitz Rojas, Giulia Zago, Melissa D. Docampo, Jacob G. Verter, Marcel R. M. van den Brink, Christopher D. Lucas, Christopher J. Anderson, Alexander Y. Rudensky, Justin S. A. Perry
The phagocytic clearance of dying cells, termed efferocytosis, is essential for both tissue homeostasis and tissue health during cell death-inducing treatments. Failure to efficiently clear dying cells augments the risk of pathological inflammation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f88d8bbaea31816b390ff1793ac56b0
https://doi.org/10.1101/2022.08.17.504322
https://doi.org/10.1101/2022.08.17.504322
Autor:
Lieselotte Vande Walle, Irma B Stowe, Pavel Šácha, Bettina L Lee, Dieter Demon, Amelie Fossoul, Filip Van Hauwermeiren, Pedro H V Saavedra, Petr Šimon, Vladimír Šubr, Libor Kostka, Craig E Stivala, Victoria C Pham, Steven T Staben, Sayumi Yamazoe, Jan Konvalinka, Nobuhiko Kayagaki, Mohamed Lamkanfi
Publikováno v:
PLoS Biology, Vol 17, Iss 10, p e3000529 (2019)
[This corrects the article DOI: 10.1371/journal.pbio.3000354.].
Externí odkaz:
https://doaj.org/article/608abbed317f4c6598fe817ed9e170da
Autor:
Lieselotte Vande Walle, Irma B Stowe, Pavel Šácha, Bettina L Lee, Dieter Demon, Amelie Fossoul, Filip Van Hauwermeiren, Pedro H V Saavedra, Petr Šimon, Vladimír Šubrt, Libor Kostka, Craig E Stivala, Victoria C Pham, Steven T Staben, Sayumi Yamazoe, Jan Konvalinka, Nobuhiko Kayagaki, Mohamed Lamkanfi
Publikováno v:
PLoS Biology, Vol 17, Iss 9, p e3000354 (2019)
The nucleotide-binding-domain (NBD)-and leucine-rich repeat (LRR)-containing (NLR) family, pyrin-domain-containing 3 (NLRP3) inflammasome drives pathological inflammation in a suite of autoimmune, metabolic, malignant, and neurodegenerative diseases.
Externí odkaz:
https://doaj.org/article/8bd2f4be33dd49be835f2a73d22da938