Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Pedro H. C. Cruz"'
Autor:
Masanori Yoshinaga, Kyuho Han, David W. Morgens, Takuro Horii, Ryosuke Kobayashi, Tatsuaki Tsuruyama, Fabian Hia, Shota Yasukura, Asako Kajiya, Ting Cai, Pedro H. C. Cruz, Alexis Vandenbon, Yutaka Suzuki, Yukio Kawahara, Izuho Hatada, Michael C. Bassik, Osamu Takeuchi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
In this work, Yoshinaga et al. use functional CRISPR screens and in vivo analyses to show that an RNA methyltransferase METTL16 and MTR4-nuclear exosome play an essential role in maintaining erythropoiesis and regulating DNA repair in erythroblasts.
Externí odkaz:
https://doaj.org/article/f78942b01fb44792b4c4ca4cc22d55e8
Autor:
Masanori, Yoshinaga, Kyuho, Han, David W, Morgens, Takuro, Horii, Ryosuke, Kobayashi, Tatsuaki, Tsuruyama, Fabian, Hia, Shota, Yasukura, Asako, Kajiya, Ting, Cai, Pedro H C, Cruz, Alexis, Vandenbon, Yutaka, Suzuki, Yukio, Kawahara, Izuho, Hatada, Michael C, Bassik, Osamu, Takeuchi
Publikováno v:
Nature communications. 13(1)
During erythroid differentiation, the maintenance of genome integrity is key for the success of multiple rounds of cell division. However, molecular mechanisms coordinating the expression of DNA repair machinery in erythroid progenitors are poorly un