Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Pedro Guillen"'
Autor:
Chao Wang, Ruben Rabadan Ros, Paloma Martinez-Redondo, Zaijun Ma, Lei Shi, Yuan Xue, Isabel Guillen-Guillen, Ling Huang, Tomoaki Hishida, Hsin-Kai Liao, Estrella Nuñez Delicado, Concepcion Rodriguez Esteban, Pedro Guillen-Garcia, Pradeep Reddy, Juan Carlos Izpisua Belmonte
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Short term systemic expression of the reprogramming factors Oct-3/4, Sox2, Klf4, c-Myc (OSKM) rejuvenates aging cells and promotes tissue regeneration. Here the authors show that myofiber-specific expression of OSKM accelerates muscle regeneration by
Externí odkaz:
https://doaj.org/article/ec46029f8e914da49e6eeddd4f0bc4ed
Autor:
Willem Van Der Merwe, Martin Lind, Peter Faunø, Kees Van Egmond, Stefano Zaffagnini, Maurilio Marcacci, Ramon Cugat, Rene Verdonk, Enrique Ibañez, Pedro Guillen, Giulio Maria Marcheggiani Muccioli
Publikováno v:
Journal of Experimental Orthopaedics, Vol 7, Iss 1, Pp 1-14 (2020)
Abstract Purpose To evaluate clinical ad radiological outcomes of anterior cruciate ligament (ACL) reconstruction with an immunochemically modified porcine patellar tendon xenograft controlled against human Achilles tendon allograft at 24-month minim
Externí odkaz:
https://doaj.org/article/44f3d24929f74027a75370123e77eed6
Autor:
Paloma Martinez-Redondo, Isabel Guillen-Guillen, Noah Davidsohn, Chao Wang, Javier Prieto, Masakazu Kurita, Fumiyuki Hatanaka, Cuiqing Zhong, Reyna Hernandez-Benitez, Tomoaki Hishida, Takashi Lezaki, Akihisa Sakamoto, Amy N. Nemeth, Yuriko Hishida, Concepcion Rodriguez Esteban, Kensaku Shojima, Ling Huang, Maxim Shokhirev, Estrella Nuñez-Delicado, Josep M. Campistol, Isabel Guillen-Vicente, Elena Rodriguez-Iñigo, Juan Manuel Lopez-Alcorocho, Marta Guillen-Vicente, George Church, Pradeep Reddy, Pedro Guillen-Garcia, Guang-Hui Liu, Juan Carlos Izpisua Belmonte
Publikováno v:
Protein & Cell, Vol 11, Iss 3, Pp 219-226 (2020)
Externí odkaz:
https://doaj.org/article/37783dd84b5348adb38d66fcf9ff720f
Autor:
Liping Deng, Ruotong Ren, Zunpeng Liu, Moshi Song, Jingyi Li, Zeming Wu, Xiaoqing Ren, Lina Fu, Wei Li, Weiqi Zhang, Pedro Guillen, Juan Carlos Izpisua Belmonte, Piu Chan, Jing Qu, Guang-Hui Liu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
DGCR8 is a component of the canonical microprocessor complex for microRNA biogenesis. Here the authors implicate DGCR8 in heterochromatin maintenance and aging attenuation independent of its miRNA-processing activity through Lamin B1, KAP1 and HP1 in
Externí odkaz:
https://doaj.org/article/ef27753ea31d478c8881938090f2b42a
Autor:
Tomoaki Hishida, Eric Vazquez-Ferrer, Yuriko Hishida-Nozaki, Ignacio Sancho-Martinez, Yuta Takahashi, Fumiyuki Hatanaka, Jun Wu, Alejandro Ocampo, Pradeep Reddy, Min-Zu Wu, Laurie Gerken, Reuben J. Shaw, Concepcion Rodriguez Esteban, Christopher Benner, Hiroshi Nakagawa, Pedro Guillen Garcia, Estrella Nuñez Delicado, Antoni Castells, Josep M. Campistol, Guang-Hui Liu, Juan Carlos Izpisua Belmonte
Publikováno v:
Protein & Cell, Vol 10, Iss 7, Pp 485-495 (2019)
Abstract Identification of the precise molecular pathways involved in oncogene-induced transformation may help us gain a better understanding of tumor initiation and promotion. Here, we demonstrate that SOX2+ foregut epithelial cells are prone to onc
Externí odkaz:
https://doaj.org/article/650bfe1468004174b4f346e6bcc81813
Autor:
Pedro Guillen de la Cruz, EfraÃn De La Cruz Lázaro, Guillermo Castañon Najera, Rodolfo Osorio Osorio, Nancy Patricia Brito Manzano, Alejandro Lozano del RÃo, Ulises López Noverola
Publikováno v:
Tropical and Subtropical Agroecosystems, Vol 10, Iss 1, Pp 101-107 (2008)
Eight tropical maize populations were crossed in a diallel system. Parent and their 28 crosses were evaluated for grain yield in two plantations in 2006. The objective was to estimate the general combining ability (GCA) of the parental populations an
Externí odkaz:
https://doaj.org/article/eee3080927a54300a1c9ead290f8acbc
Autor:
Kristen C. Browder, Pradeep Reddy, Mako Yamamoto, Amin Haghani, Isabel Guillen Guillen, Sanjeeb Sahu, Chao Wang, Yosu Luque, Javier Prieto, Lei Shi, Kensaku Shojima, Tomoaki Hishida, Zijuan Lai, Qingling Li, Feroza K. Choudhury, Weng R. Wong, Yuxin Liang, Dewakar Sangaraju, Wendy Sandoval, Concepcion Rodriguez Esteban, Estrella Nuñez Delicado, Pedro Guillen Garcia, Michal Pawlak, Jason A. Vander Heiden, Steve Horvath, Heinrich Jasper, Juan Carlos Izpisua Belmonte
Publikováno v:
Nature Aging. 2:243-253
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46a7b1d59e48387a5aaec6f5f65b72e3
https://doi.org/10.1038/s43587-022-00183-2
https://doi.org/10.1038/s43587-022-00183-2
Publikováno v:
35th International Pipeline Pigging and Integrity Management Conference (PPIM 2023).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88b9a6fcae7878718514b214b20ec3da
https://doi.org/10.52202/068696-0021
https://doi.org/10.52202/068696-0021
Autor:
Hishida, Tomoaki, Yamamoto, Mako, Hishida-Nozaki, Yuriko, Shao, Changwei, Huang, Ling, Wang, Chao, Shojima, Kensaku, Xue, Yuan, Hang, Yuqing, Shokhirev, Maxim, Memczak, Sebastian, Sahu, Sanjeeb Kumar, Hatanaka, Fumiyuki, Ros, Ruben Rabadan, Maxwell, Matthew B, Chavez, Jasmine, Shao, Yanjiao, Liao, Hsin-Kai, Martinez-Redondo, Paloma, Guillen-Guillen, Isabel, Hernandez-Benitez, Reyna, Esteban, Concepcion Rodriguez, Qu, Jing, Holmes, Michael C, Yi, Fei, Hickey, Raymond D, Garcia, Pedro Guillen, Delicado, Estrella Nuñez, Castells, Antoni, Campistol, Josep M, Yu, Yang, Hargreaves, Diana C, Asai, Akihiro, Reddy, Pradeep, Liu, Guang-Hui, Izpisua Belmonte, Juan Carlos
Publikováno v:
Cell reports, vol 39, iss 4
Mammals have limited regenerative capacity, whereas some vertebrates, like fish and salamanders, are able to regenerate their organs efficiently. The regeneration in these species depends on cell dedifferentiation followed by proliferation. We genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::af4dbde436b6ae000f21164e5cbfb54d
https://escholarship.org/uc/item/1xd3j4bj
https://escholarship.org/uc/item/1xd3j4bj
Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration
Autor:
Jing Qu, Pedro Guillen, Kaowen Yan, Piu Chan, Liang Sun, Si Wang, Yanning Cai, Tomoaki Hishida, Zeming Wu, Weiqi Zhang, Qiaoran Wang, Juan Carlos Izpisua Belmonte, Chuqian Liang, Zehua Wang, Wei Li, Qi Zhou, Moshi Song, Guang-Hui Liu, Zunpeng Liu
Publikováno v:
Cell Research
Accumulating evidence indicates an association between the circadian clock and the aging process. However, it remains elusive whether the deregulation of circadian clock proteins underlies stem cell aging and whether they are targetable for the allev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c879d9a9a7d4ef5e3868e517d4f02e
https://doi.org/10.1038/s41422-020-0385-7
https://doi.org/10.1038/s41422-020-0385-7