Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Pedro García-Gómez"'
Autor:
Beatriz Ocaña-Tienda, Julián Pérez-Beteta, Juan Jiménez-Sánchez, David Molina-García, Ana Ortiz de Mendivil, Beatriz Asenjo, David Albillo, Luis A. Pérez-Romasanta, Manuel Valiente, Lucía Zhu, Pedro García-Gómez, Elisabet González-Del Portillo, Manuel Llorente, Natalia Carballo, Estanislao Arana, Víctor M. Pérez-García
Publikováno v:
npj Systems Biology and Applications, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Tumor growth is the result of the interplay of complex biological processes in huge numbers of individual cells living in changing environments. Effective simple mathematical laws have been shown to describe tumor growth in vitro, or simple
Externí odkaz:
https://doaj.org/article/23ac769d1d63464d85af6bdbd91fb365
Autor:
Pedro García‐Gómez, Irene Golán, Mahsa S. Dadras, Artur Mezheyeuski, Claudia Bellomo, Kalliopi Tzavlaki, Anita Morén, Jordi Carreras‐Puigvert, Laia Caja
Publikováno v:
Molecular Oncology, Vol 16, Iss 9, Pp 1891-1912 (2022)
Glioblastoma (GBM) is the most aggressive and common glioma subtype, with a median survival of 15 months after diagnosis. Current treatments have limited therapeutic efficacy; thus, more effective approaches are needed. The glioblastoma tumoural mass
Externí odkaz:
https://doaj.org/article/bcbbc3ef2f3e4c95b309c91559fbcb09
Autor:
Lucía Zhu, Diana Retana, Pedro García‐Gómez, Laura Álvaro‐Espinosa, Neibla Priego, Mariam Masmudi‐Martín, Natalia Yebra, Lauritz Miarka, Elena Hernández‐Encinas, Carmen Blanco‐Aparicio, Sonia Martínez, Cecilia Sobrino, Nuria Ajenjo, Maria‐Jesus Artiga, Eva Ortega‐Paino, Raúl Torres‐Ruiz, Sandra Rodríguez‐Perales, RENACER, Riccardo Soffietti, Luca Bertero, Paola Cassoni, Tobias Weiss, Javier Muñoz, Juan Manuel Sepúlveda, Pedro González‐León, Luis Jiménez‐Roldán, Luis Miguel Moreno, Olga Esteban, Ángel Pérez‐Núñez, Aurelio Hernández‐Laín, Oscar Toldos, Yolanda Ruano, Lucía Alcázar, Guillermo Blasco, José Fernández‐Alén, Eduardo Caleiras, Miguel Lafarga, Diego Megías, Osvaldo Graña‐Castro, Carolina Nör, Michael D Taylor, Leonie S Young, Damir Varešlija, Nicola Cosgrove, Fergus J Couch, Lorena Cussó, Manuel Desco, Silvana Mouron, Miguel Quintela‐Fandino, Michael Weller, Joaquín Pastor, Manuel Valiente, Adolfo de la Lama‐Zaragoza, Lourdes Calero‐Felix, Concepcion Fiaño‐Valverde, Pedro David Delgado‐López, Antonio Montalvo‐Afonso, Mar Pascual‐Llorente, Ángela Díaz‐Piqueras, SH Nam‐Cha, Cristina Barrena López, Gerard Plans Ahicart, Elena Martínez‐Saez, Santiago Ramón y Cajal, Pilar Nicolás
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 3, Pp 1-29 (2022)
Abstract We report a medium‐throughput drug‐screening platform (METPlatform) based on organotypic cultures that allows to evaluate inhibitors against metastases growing in situ. By applying this approach to the unmet clinical need of brain metast
Externí odkaz:
https://doaj.org/article/192ccb44b2e3449a849f6353de0e50dd
Autor:
Neibla Priego, Pedro García-Gómez, Ana de Pablos-Aragoneses, María Perea-García, Laura Álvaro-Espinosa, Carolina Hernández-Oliver, Elena Martínez-Saez, Ángel Pérez-Núñez, Aurelio Hernández-Laín, Rebeca Sanz-Pamplona, Marc Schmitz, Stephen J. Crocker, Diego Serrano, Asís Palazón, RENACER Red Nacional de Metástasis Cerebral, Manuel Valiente
Publikováno v:
Cancer Research. 83:5105-5105
Brain metastasis is an unmet clinical need, affecting between 10-30% of cancer patients with 200000 to 400000 newly diagnosis per annum in the US. Recently, several clinical trials have reported benefits using immunotherapy to treat brain metastasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af0af6931783dc6d5df14ff0c36e3ff3
https://doi.org/10.1158/1538-7445.am2023-5105
https://doi.org/10.1158/1538-7445.am2023-5105
Autor:
Pedro García-Gómez, Diana Retana, Pablo Sanz-Martínez, Irene Salgado-Crespo, Carolina Hernández-Oliver, Maria Isabel García, Oliva Sánchez, Kevin Troulé-Lozano, Verona Villar-Cerviño, Miguel Lafarga-Coscojuela, Fátima Al-Shahrour, RENACER Red Nacional de Metástasis Cerebral, Manuel Valiente
Publikováno v:
Cancer Research. 83:3516-3516
The physical interaction between metastasis-initiating cells and the pre-existing capillary network (a process known as vascular co-option) is critical during the initial stages of multi-organ metastasis in cancer. As such, this process might provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98b3429031165f4dbb99544404cb6718
https://doi.org/10.1158/1538-7445.am2023-3516
https://doi.org/10.1158/1538-7445.am2023-3516
Autor:
Ángel Acosta Rojas, Esther Hernández-San Miguel, María Pérez-Cano, Gabriel F. Calvo, Lucía Zhu, Ana María García Vicente, Juan Belmonte-Beitia, Juan J. Jiménez, David Albillo, Philippe Schucht, Víctor M. Pérez-García, Pedro García-Gómez, Antonio Francisco Honguero Martínez, François M. Vallette, Manuel Valiente, Jesús J. Bosque, Álvaro Martínez, Julián Pérez-Beteta, David Molina-García, Youness Azimzade, Odelaisy León-Triana, Michael Murek, Pilar Sánchez-Gómez, Ana Ortiz de Mendivil, Rafael Hortigüela, Germán Andrés Jiménez Londoño, Estanislao Arana
Publikováno v:
Nature Physics
Nature Physics, Nature Publishing Group, 2020, Online ahead of print. ⟨10.1038/s41567-020-0978-6⟩
Nat Phys
RUIdeRA. Repositorio Institucional de la UCLM
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Physics, 2020, Online ahead of print. ⟨10.1038/s41567-020-0978-6⟩
Nature Physics, Nature Publishing Group, 2020, Online ahead of print. ⟨10.1038/s41567-020-0978-6⟩
Nat Phys
RUIdeRA. Repositorio Institucional de la UCLM
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Physics, 2020, Online ahead of print. ⟨10.1038/s41567-020-0978-6⟩
Most physical and other natural systems are complex entities composed of a large number of interacting individual elements. It is a surprising fact that they often obey the so-called scaling laws relating an observable quantity with a measure of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ef2f8e9c4b03dd80583491c081de81
https://doi.org/10.1038/s41567-020-0978-6
https://doi.org/10.1038/s41567-020-0978-6
Autor:
Beatriz Ocaña-Tienda, Julián Pérez-Beteta, Juan Jiménez-Sánchez, David Molina García, Ana Ortiz de Mendivil, Beatriz Asenjo, David Albillo, Luís A. Pérez-Romasanta, Manuel Valiente, Lucía Zhu, Pedro García-Gómez, Elisabet González-Del Portillo, Manuel Llorente, Natalia Carballo, Estanislao Arana, Víctor M. Pérez-García
Tumor growth is the result of the interplay of complex biological processes in huge numbers of individual cells living in changing environments. Effective simple mathematical laws have been shown to describe tumor growth in vitro, or simple animal mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cdcce7185600a43e4e30592d880c4c0
https://doi.org/10.1101/2022.02.03.22270146
https://doi.org/10.1101/2022.02.03.22270146
Autor:
Pedro García-Gómez, Manuel Valiente
Vascular co-option is an alternative mechanism to interact with blood vessels used by normal cells and hijacked by cancer cells. Functional experiments using in vivo models have demonstrated that co-option of pre-existing capillary networks is a crit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4b9a184a2a990c4efaec50a3c7a5a3d
https://doi.org/10.1016/b978-0-12-819494-2.00003-1
https://doi.org/10.1016/b978-0-12-819494-2.00003-1
Autor:
Laetitia Andrique, Andrea Barbieri, Raymond Barnhill, Andréas Bikfalvi, Yun Cao, Pedro García-Gómez, Jessica Guerra, Adrian L. Harris, Hynda Kleinman, Alia Komsany, Claire Lugassy, Pierre Nassoy, Francesco Pezzella, Marco Presta, Chao-Nan Qian, Gaelle Recher, Domenico Ribatti, Chiara Tobia, Manuel Valiente, Peter Vermeulen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ef6fcff83f928007bd1feb7c35bb991
https://doi.org/10.1016/b978-0-12-819494-2.00013-4
https://doi.org/10.1016/b978-0-12-819494-2.00013-4
Publikováno v:
Central Nervous System Metastases ISBN: 9783030234164
Repisalud
Instituto de Salud Carlos III (ISCIII)
Repisalud
Instituto de Salud Carlos III (ISCIII)
The microenvironment has emerged as a promising source of novel therapeutic applications in experimental models of brain metastasis. Our limited understanding of the complex brain ecosystem transformed by the presence of cancer cells includes key cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::561d074089dcde5b5d2f40d20eae7337
https://doi.org/10.1007/978-3-030-23417-1_5
https://doi.org/10.1007/978-3-030-23417-1_5