Výsledky vyhledávání - "Pedro Freire Jorge"

Akademický článek

Early lactate and glucose kinetics following return to spontaneous circulation after out-of-hospital cardiac arrest

Autor: Pedro Freire Jorge, Rohan Boer, Rene A. Posma, Katharina C. Harms, Bart Hiemstra, Bas W. J. Bens, Maarten W. Nijsten

Publikováno v: BMC Research Notes, Vol 14, Iss 1, Pp 1-7 (2021)

Abstract Objective Lactate has been shown to be preferentially metabolized in comparison to glucose after physiological stress, such as strenuous exercise. Derangements of lactate and glucose are common after out-of-hospital cardiac arrest (OHCA). Th

Externí odkaz: https://doaj.org/article/e7d966a0e73b4454b0f60e8d88d9cbaf

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Akademický článek

Low Cancer Incidence in Naked Mole-Rats May Be Related to Their Inability to Express the Warburg Effect

Autor: Pedro Freire Jorge, Matthew L. Goodwin, Maurits H. Renes, Maarten W. Nijsten, Matthew Pamenter

Publikováno v: Frontiers in Physiology, Vol 13 (2022)

Metabolic flexibility in mammals enables stressed tissues to generate additional ATP by converting large amounts of glucose into lactic acid; however, this process can cause transient local or systemic acidosis. Certain mammals are adapted to extreme

Externí odkaz: https://doaj.org/article/078dd50744b045ad8ee239cf56f74a71

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Akademický článek

The association of early combined lactate and glucose levels with subsequent renal and liver dysfunction and hospital mortality in critically ill patients

Autor: Pedro Freire Jorge, Nienke Wieringa, Eva de Felice, Iwan C. C. van der Horst, Annemieke Oude Lansink, Maarten W. Nijsten

Publikováno v: Critical Care, Vol 21, Iss 1, Pp 1-11 (2017)

Abstract Background The development of renal and liver dysfunction may be accompanied by initially subtle derangements in the gluconeogenetic function. Discrepantly low glucose levels combined with high lactate levels might indicate an impaired Cori

Externí odkaz: https://doaj.org/article/8cb2176263f540f8a4ebfecfe917b133

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Early lactate and glucose kinetics following return to spontaneous circulation after out-of-hospital cardiac arrest

Autor: Bart Hiemstra, Rohan Boer, Katharina C. Harms, Maarten W. N. Nijsten, Bas W. J. Bens, Pedro Freire Jorge, Rene A. Posma

Publikováno v: BMC Research Notes, 14(1):183. BioMed Central Ltd.
BMC Research Notes, Vol 14, Iss 1, Pp 1-7 (2021)
Freire Jorge, P, Boer, R, Posma, R A, Harms, K C, Hiemstra, B, Bens, B W J & Nijsten, M W 2021, ' Early lactate and glucose kinetics following return to spontaneous circulation after out-of-hospital cardiac arrest ', BMC Research Notes, vol. 14, no. 1, 183 . https://doi.org/10.1186/s13104-021-05604-w
BMC Research Notes
BMC Research Notes, 14(1):183. BioMed Central

Objective Lactate has been shown to be preferentially metabolized in comparison to glucose after physiological stress, such as strenuous exercise. Derangements of lactate and glucose are common after out-of-hospital cardiac arrest (OHCA). Therefore,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebb7b75dce398c731a597b31c706bed
https://research.rug.nl/en/publications/c0ba1102-d8a7-4db8-ad91-022474a860a6

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Ischemic priapism as a model of exhausted metabolism

Autor: Maarten W. N. Nijsten, Sanne Vreugdenhil, Mels F. van Driel, Pedro Freire Jorge

Publikováno v: Physiological Reports, Vol 7, Iss 6, Pp n/a-n/a (2019)
Physiological Reports
Physiological Reports, 7(6):13999. Wiley

In vivo metabolic studies typically concern complex open systems. However, a closed system allows better assessment of the metabolic limits. Ischemic priapism (IP) constitutes a special model of the compartment syndrome that allows direct sampling fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2054afc5c9bfd2bb9bf291f47f5b6f
https://hdl.handle.net/11370/684fd28a-575b-45f1-a117-7495ad4e9fb5

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[The Warburg effect and its role in tumour metabolism: opportunities for new cancer treatments]

Autor: Remco, van Horssen, Pedro, Freire Jorge, Gooitzen M, van Dam, Maarten W, Nijsten

Publikováno v: Nederlands tijdschrift voor geneeskunde. 160

Cancer cells are characterised by altered metabolism compared to healthy tissue. Ninety years ago, the German medical doctor and biochemist Otto Warburg discovered that tumours--when compared to healthy tissue--convert considerably more glucose into

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bc5b251e36e144283916a2ccc7442471
https://pubmed.ncbi.nlm.nih.gov/26813013

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