Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Pedro Escoll"'
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102175- (2023)
Summary: Regulation of bioenergetics and cell death are pivotal mitochondrial functions determining the responses of macrophages to infection. Here, we provide a protocol to investigate mitochondrial functions during infection of macrophages by intra
Externí odkaz:
https://doaj.org/article/6bc978c5c10243bc9fdc7a6d6c200964
Autor:
Tobias Sahr, Pedro Escoll, Christophe Rusniok, Sheryl Bui, Gérard Pehau-Arnaudet, Gregory Lavieu, Carmen Buchrieser
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Legionella pneumophila expresses a range of bacterial determinants that mimic eukaryotic functions. Here the authors show small RNAs of L.pneumophila mimic eukaryotic microRNA and modulate the host response to infection.
Externí odkaz:
https://doaj.org/article/3df97bae629b4c4cb76dc65b011ff7e6
Autor:
Ignacio Santecchia, Delphine Bonhomme, Stylianos Papadopoulos, Pedro Escoll, Alexandre Giraud-Gatineau, Maryse Moya-Nilges, Frédérique Vernel-Pauillac, Ivo Gomperts Boneca, Catherine Werts
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Leptospira interrogans are pathogenic bacteria responsible for leptospirosis, a zoonosis impacting 1 million people per year worldwide. Leptospires can infect all vertebrates, but not all hosts develop similar symptoms. Human and cattle may suffer fr
Externí odkaz:
https://doaj.org/article/33faeedf681644fc96a715f5af680349
Autor:
Pedro Escoll, Lucien Platon, Mariatou Dramé, Tobias Sahr, Silke Schmidt, Christophe Rusniok, Carmen Buchrieser
Publikováno v:
eLife, Vol 10 (2021)
Legionella pneumophila, the causative agent of Legionnaires’ disease, a severe pneumonia, injects via a type 4 secretion system (T4SS) more than 300 proteins into macrophages, its main host cell in humans. Certain of these proteins are implicated i
Externí odkaz:
https://doaj.org/article/61a858dc6ffb4cb69321f87988334e37
Autor:
Ina Häuslein, Tobias Sahr, Pedro Escoll, Nadine Klausner, Wolfgang Eisenreich, Carmen Buchrieser
Publikováno v:
Open Biology, Vol 7, Iss 11 (2017)
Legionella pneumophila CsrA plays a crucial role in the life-stage-specific expression of virulence phenotypes and metabolic activity. However, its exact role is only partly known. To elucidate how CsrA impacts L. pneumophila metabolism we analysed t
Externí odkaz:
https://doaj.org/article/6cf6aeb409d84909b9cad4bc67c8a089
Autor:
Pedro Escoll, Ismael Ranz, Norman Muñoz-Antón, Ana van-den-Rym, Melchor Alvarez-Mon, Carlos Martínez-Alonso, Eva Sanz, Antonio de-la-Hera
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Clinical treatment with glucocorticoids (GC) can be complicated by cytokine-induced glucocorticoid low-responsiveness (GC-resistance, GCR), a condition associated with a homogeneous reduction in the expression of GC-receptor- (GR-) driven anti-inflam
Externí odkaz:
https://doaj.org/article/6a9f204788ba4601865361b5c29efc5f
Autor:
Mélissa Erin Khan, Chloé Borde, Eduardo P C Rocha, Véronique Mériaux, Vincent Maréchal, Pedro Escoll, Sophie Goyard, Jean-Marc Cavaillon, Bénédicte Manoury, Noëlle Doyen
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 11, p e3308 (2014)
DNA sequences purified from distinct organisms, e.g. non vertebrate versus vertebrate ones, were shown to differ in their TLR9 signalling properties especially when either mouse bone marrow-derived- or human dendritic cells (DCs) are probed as target
Externí odkaz:
https://doaj.org/article/d86f9af2179f47cda91144f92049eace
Autor:
Alba Galan, Pauline Dergham, Pedro Escoll, Antonio de-la-Hera, Philippe M D'Onofrio, Mark M Magharious, Paulo D Koeberle, José María Frade, H Uri Saragovi
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101349 (2014)
Retinal ganglion cells (RGCs) are neurons that relay visual signals from the retina to the brain. The RGC cell bodies reside in the retina and their fibers form the optic nerve. Full transection (axotomy) of the optic nerve is an extra-retinal injury
Externí odkaz:
https://doaj.org/article/0813c48195554d0faa8ac438f040f18e
Autor:
Pedro Escoll
Infectious diseases continue to be a major threat to human health with predictions that these will account for one of five deaths globally over the coming decades. The worrying rise in antibiotic resistance in bacterial pathogens only serves to exace
Publikováno v:
Mitochondria and Bacterial Pathogens Part A
Saverio Marchi-Marche Polytechnic University, Ancona, Italy; Lorenzo Galluzzi-Weill Cornell Medical College, New York, NY, United States. Mitochondria and Bacterial Pathogens Part A, 374, Elsevier Inc, pp.37-81, 2023, International Review of Cell and Molecular Biology, ISSN 1937-6448. ⟨10.1016/bs.ircmb.2022.10.001⟩
Mitochondria and Bacterial Pathogens Part A ISBN: 9780323994033
Saverio Marchi-Marche Polytechnic University, Ancona, Italy; Lorenzo Galluzzi-Weill Cornell Medical College, New York, NY, United States. Mitochondria and Bacterial Pathogens Part A, 374, Elsevier Inc, pp.37-81, 2023, International Review of Cell and Molecular Biology, ISSN 1937-6448. ⟨10.1016/bs.ircmb.2022.10.001⟩
Mitochondria and Bacterial Pathogens Part A ISBN: 9780323994033
International audience; Legionella pneumophila is the causative agent of Legionnaires’ disease, a severe pneumonia. L. pneumophila injects via a type-IV-secretion-system (T4SS) more than 300 bacterial proteins into macrophages, its main host cell i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26be71fad896c18527221a8cd7974f2b
https://hal-pasteur.archives-ouvertes.fr/pasteur-04132531
https://hal-pasteur.archives-ouvertes.fr/pasteur-04132531