Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pedro De Jesús Cruz"'
Publikováno v:
Journal of the American Chemical Society. 144(34)
Tetrasubstituted stereogenic carbon centers bearing a nitrogen substituent represent important motifs in medicinal chemistry and natural products; therefore, the development of efficient methods for the stereoselective synthesis of this class of comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a9f50512b99c5fb7b8a0fea23103754
https://pubmed.ncbi.nlm.nih.gov/35980759
https://pubmed.ncbi.nlm.nih.gov/35980759
Publikováno v:
Journal of the American Chemical Society. 144:15803-15811
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9fb0f43a8e1ebfed1e6bda6fdad4075
https://doi.org/10.1021/jacs.2c06669
https://doi.org/10.1021/jacs.2c06669
Publikováno v:
Science
Synthetic methods that enable simultaneous control over multiple stereogenic centers are desirable for the efficient preparation of pharmaceutical compounds. Herein, we report the discovery and development of a catalyst-mediated asymmetric Michael ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ee268830d5ee5e79d6cb9821e88c21
https://pubmed.ncbi.nlm.nih.gov/35679416
https://pubmed.ncbi.nlm.nih.gov/35679416
Autor:
Mitchell T. Giordano, Katelyn M. Kitzinger, Pedro de Jesús Cruz, Shubin Liu, Jeffrey S. Johnson
Publikováno v:
Journal of the American Chemical Society.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3be5665d7f2f9bea5e0c1d69ef9209b3
https://doi.org/10.1021/jacs.3c03373
https://doi.org/10.1021/jacs.3c03373
Publikováno v:
Org Lett
Progress toward a convergent approach for the enantioselective synthesis of the Veratrum alkaloid jervine is presented. The two requisite fragments were stereoselectively and efficiently fashioned from economical and readily available reagents. Key r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4533e3c7b5a27b0d5a880865b0ca051c
https://doi.org/10.1021/acs.orglett.0c00972
https://doi.org/10.1021/acs.orglett.0c00972
Publikováno v:
J Am Chem Soc
Additions of carbon nucleophiles to racemic α-stereogenic β-oxo acid derivatives that deliver enantiomerically enriched tertiary alcohols are valuable, but uncommon. This article describes stereodivergent Cu-catalyzed borylative cyclizations of rac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1bbbea65df36dbf32e1cc6bd2d1586
https://europepmc.org/articles/PMC8497423/
https://europepmc.org/articles/PMC8497423/
Autor:
Nathan Fisher, Pedro De Jesús Cruz, Mark H. Schoenfisch, Mona Jasmine R. Ahonen, Terry Kougoulos
Publikováno v:
Open Forum Infectious Diseases
Background Multi-drug resistant superbugs are a serious health threat due to limited treatment options and high mortality rates. Certain superbug strains are now resistant to as many as 36 representative FDA-approved antibiotics, including Colistin a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d621dfb88305689e3989f8caf41c2be
http://europepmc.org/articles/PMC5631293
http://europepmc.org/articles/PMC5631293