Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Pedro Beltran-Alvarez"'
Autor:
Edward Gilbert, Anamarija Žagar, Marta López-Darias, Rodrigo Megía-Palma, Karen A. Lister, Max Dolton Jones, Miguel A. Carretero, Nina Serén, Pedro Beltran-Alvarez, Katharina C. Wollenberg Valero
Publikováno v:
PLoS ONE, Vol 19, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/01f3997835194e55998b5fad860981e9
Autor:
Lucie J. Bilton, Chloe Warren, Rebecca M. Humphries, Shannon Kalsi, Ella Waters, Thomas Francis, Wojtek Dobrowinski, Pedro Beltran-Alvarez, Mark A. Wade
Publikováno v:
Cancers, Vol 14, Iss 14, p 3491 (2022)
Chromobox 2 (CBX2) is a chromatin-binding component of polycomb repressive complex 1, which causes gene silencing. CBX2 expression is elevated in triple-negative breast cancer (TNBC), for which there are few therapeutic options. Here, we aimed to inv
Externí odkaz:
https://doaj.org/article/efbb27b6aacc40d4bf1a3cec6307e539
Autor:
Sabrina Francesca Samuel, Alistair James Marsden, Srihari Deepak, Francisco Rivero, John Greenman, Pedro Beltran-Alvarez
Publikováno v:
Proteomes, Vol 6, Iss 4, p 44 (2018)
Glioblastomas (GBM) are the most common grade 4 brain tumours; patients have very poor prognosis with an average survival of 15 months after diagnosis. Novel research lines have begun to explore aberrant protein arginine methylation (ArgMe) as a poss
Externí odkaz:
https://doaj.org/article/f051a331a81f4d278ccd606efac1dae3
Autor:
Anna Tarradas, Elisabet Selga, Pedro Beltran-Alvarez, Alexandra Pérez-Serra, Helena Riuró, Ferran Picó, Anna Iglesias, Oscar Campuzano, Víctor Castro-Urda, Ignacio Fernández-Lozano, Guillermo J Pérez, Fabiana S Scornik, Ramon Brugada
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53220 (2013)
Brugada syndrome (BrS) is a life-threatening, inherited arrhythmogenic syndrome associated with autosomal dominant mutations in SCN5A, the gene encoding the cardiac Na(+) channel alpha subunit (Na(v)1.5). The aim of this work was to characterize the
Externí odkaz:
https://doaj.org/article/f35596f2e5fc4cb8a5efbfd0cbb568cf
Autor:
Oriol Gallego, Matthew J Betts, Jelena Gvozdenovic‐Jeremic, Kenji Maeda, Christian Matetzki, Carmen Aguilar‐Gurrieri, Pedro Beltran‐Alvarez, Stefan Bonn, Carlos Fernández‐Tornero, Lars Juhl Jensen, Michael Kuhn, Jamie Trott, Vladimir Rybin, Christoph W Müller, Peer Bork, Marko Kaksonen, Robert B Russell, Anne‐Claude Gavin
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp n/a-n/a (2010)
Protein–metabolite networks are central to biological systems, but are incompletely understood. Here, we report a screen to catalog protein–lipid interactions in yeast. We used arrays of 56 metabolites to measure lipid‐binding fingerprints of 1
Externí odkaz:
https://doaj.org/article/f43378c8acc249edbcfa2446039a4d6c
Autor:
Lauric Feugere, Adam Bates, Timothy Emagbetere, Emma Chapman, Linsey E Malcolm, Kathleen Bulmer, Jörg Hardege, Pedro Beltran-Alvarez, Katharina C Wollenberg Valero
Publikováno v:
PNAS Nexus. 2
Heat alters biology from molecular to ecological levels, but may also have unknown indirect effects. This includes the concept that animals exposed to abiotic stress can induce stress in naive receivers. Here, we provide a comprehensive picture of th
Autor:
Antonia Barry, Sabrina F. Samuel, Ines Hosni, Amr Moursi, Lauric Feugere, Christopher J. Sennett, Srihari Deepak, Shailendra Achawal, Chittoor Rajaraman, Alexander Iles, Katharina C. Wollenberg Valero, Ian S. Scott, Vicky Green, Lucy F. Stead, John Greenman, Mark A. Wade, Pedro Beltran-Alvarez
Publikováno v:
Lab on a Chip.
Treatment of human brain tumour biopsies, maintained on-chip, with type I PRMT inhibitors leads to apoptosis through changes in gene expression and RNA processing, mediated by cross-talk with type II PRMT.
Autor:
Iker Irisarri, Lauric Feugere, Johannes Müller, Adam Bates, Joan Garcia-Porta, Katharina C. Wollenberg Valero, Pedro Beltran-Alvarez, Alexander P. Turner, Sebastian Kirchhof, Panayiotis Pafilis, Miguel Vences, Kenneth B. Storey, Sabrina Francesca Samuel, Olga Jovanović Glavaš
Publikováno v:
Journal of Animal Ecology. 91:1163-1179
Understanding the genomic basis of adaptation to different abiotic environments is important in the context of climate change and resulting short-term environmental fluctuations. Using functional and comparative genomics approaches, we here investiga
Autor:
Francisco Rivero, Barbara-Ann Guinn, Pedro Beltran-Alvarez, David R. J. Riley, Neil T. Kemp, Antonia Barry, Jawad S. Khalil, Alistair James Marsden
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] Protein arginine methyltransferases (PRMTs) catalyze the transfer of methyl groups to arginine residues in proteins. PRMT inhibitors are novel, promising drugs against cancer that are currently in clinical trials, which include oral
Autor:
Lauric Feugere, Adam Bates, Timothy Emagbetere, Emma Chapman, Linsey Malcolm, Kathleen Bulmer, Jörg Hardege, Pedro Beltran-Alvarez, Katharina C. Wollenberg Valero
Heat alters biology from molecular to ecological levels, but may also have unknown indirect effects. This includes the novel concept that animals exposed to abiotic stress can induce stress in naive receivers. Here, we provide a comprehensive picture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14e40835c693b1c0e4a95ced12615025
https://doi.org/10.1101/2022.09.15.508176
https://doi.org/10.1101/2022.09.15.508176