Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Pedro Ayala"'
Autor:
Renatto Anfossi, Raúl Vivar, Pedro Ayala, Fabiola González-Herrera, Claudio Espinoza-Pérez, José Miguel Osorio, Mauricio Román-Torres, Samir Bolívar, Guillermo Díaz-Araya
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Cardiac fibroblasts (CF) are crucial cells in damaged heart tissues, expressing TLR4, IFN-receptor and responding to lipopolysaccharide (LPS) and interferon-β (IFN-β) respectively. While CF interact with immune cells; however, their r
Externí odkaz:
https://doaj.org/article/ff2d036fafee46b78b4f239e3e959d5a
Autor:
Guiliana Mas-Ubillus, Pedro J. Ortiz, Jorge Huaringa-Marcelo, Paola Sarzo-Miranda, Patricia Muñoz-Aguirre, Alejandra Diaz-Ramos, Kattia Arribasplata-Purizaca, Doris Mendoza, Juan Rojas-Poma, Cristian Marcelo-Ruiz, Pedro Ayala-Diaz, Edwin Hidalgo-Arroyo, Lourdes Tupia-Cespedes
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Background Peru is the country with the world’s highest COVID-19 death rate per capita. Characteristics associated with increased mortality among adult patients with COVID-19 pneumonia in this setting are not well described. Methods Retrospective,
Externí odkaz:
https://doaj.org/article/c9f0aef6d58a48a8b6a78b530bfca945
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Alveolar architecture plays a fundamental role in the processes of ventilation and perfusion in the lung. Alterations in the alveolar surface area and alveolar cavity volume constitute the pathophysiological basis of chronic respiratory diseases such
Externí odkaz:
https://doaj.org/article/de7e269e84944c319f12ef7824049ce9
Autor:
Pablo Parra-Flores, Jenaro Espitia-Corredor, Claudio Espinoza-Pérez, Cristian Queirolo, Pedro Ayala, Francisca Brüggendieck, Aimee Salas-Hernández, Viviana Pardo-Jiménez, Guillermo Díaz-Araya
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Death of cardiac fibroblasts (CFs) by ischemia/reperfusion (I/R) has major implications for cardiac wound healing. In in vivo models of myocardial infarction, toll-like receptor 4 (TLR4) activation has been reported as a cardioprotector; however, it
Externí odkaz:
https://doaj.org/article/736c4b9ac2144a8a862cc174b0b9a82c
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background Gastric contents aspiration is a high-risk condition for acute lung injury (ALI). Consequences range from subclinical pneumonitis to respiratory failure, depending on the volume of aspirate. A large increment in inflammatory cells
Externí odkaz:
https://doaj.org/article/de3374f16cb542e98e059162df8108e6
Autor:
Pedro Ayala, Jorge Torres, Raúl Vivar, Manuel Meneses, Pablo Olmos, Tamara San Martin, Gisella R. Borzone
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Gastric contents aspiration in humans has variable consequences depending on the volume of aspirate, ranging from subclinical pneumonitis to respiratory failure with up to 70% mortality. Several experimental approaches have been u
Externí odkaz:
https://doaj.org/article/ac42761498e04dc08c39e1f97c7f1031
Autor:
Carolina Cruz de Sousa, Ana, da Silva Santos, Elias, da Silva Moreira, Thais, Gabriela Araújo Mendes, Maria, Rodrigues Arruda, Bruno, de Jesus Guimarães, Celina, de Brito Vieira Neto, José, Santiago de Oliveira, Yara, Pedro Ayala, Alejandro, Rodrigues da Costa, Mac Dionys, Lima Sampaio, Tiago, Paula Negreiros Nunes Alves, Ana, Pessoa, Cláudia, Petrilli, Raquel, Eloy, Josimar O.
Publikováno v:
In International Journal of Pharmaceutics 15 August 2024 661
Autor:
Chaudhary, Rajni, Yadav, Arti, Singh Bahota, Ashok, Singh, Swapnil, de Castro Fonseca, Jéssica, Pedro Ayala, Alejandro, Prasad, Veena, Tandon, Poonam
Publikováno v:
In Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 5 July 2023 295
A binuclear Fe(iii )/quinizarin complex as a structural model for anthracycline drugs binding to iron
Autor:
Juliana S. do Nascimento, Aurideia P. de Sousa, Ana C. S. Gondim, Eduardo H. S. Sousa, Edson H. Teixeira, Luiz Gonzaga do Nascimento Neto, Beatriz Pinheiro Bezerra, Alejandro Pedro Ayala, Alzir A. Batista, Igor F. Vasconcelos, Francisco G. S. Oliveira, Alda K. M. Holanda
Publikováno v:
New Journal of Chemistry. 46:5515-5525
Quinizarin, an anthracyclin-like compound, was used to prepare a binuclear complex, [(Fe(cyclam))2Qz]Cl(PF6)3, which showed damage to DNA with glutathione. This mimic of anthracyclin drugs might explain undesired side effects of these compounds.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc14c921199e4e1c43f561f3b378d720
https://doi.org/10.1039/d1nj04087a
https://doi.org/10.1039/d1nj04087a
Publikováno v:
CrystEngComm.
In contrast to the widespread polymorphism of single component drugs, polymorphism in cocrystals is still uncommon and often poorly understood. While there are numerous reports of polymorphic forms of single...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e54b7c7774043857ed94144e838ef7c1
https://doi.org/10.1039/d3ce00103b
https://doi.org/10.1039/d3ce00103b