Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Pedro A. Sánchez‐Murcia"'
Autor:
Hao Ye, Carlos Franco, Mostafa A. Aboouf, Markus Thiersch, Semih Sevim, Joaquin Llacer‐Wintle, Andrea Veciana, Gemma Llauradó‐Capdevila, Kaiyuan Wang, Xiang‐Zhong Chen, Qiao Tang, Roc Matheu, Pedro D. Wendel‐Garcia, Pedro A. Sánchez‐Murcia, Bradley J. Nelson, Cong Luo, Josep Puigmartí‐Luis, Salvador Pané
Publikováno v:
Advanced Science, Vol 11, Iss 44, Pp n/a-n/a (2024)
Abstract Covalent Organic Frameworks (COFs) emerged as versatile materials with promising potential in biomedicine. Their customizable functionalities and tunable pore structures make them valuable for various biomedical applications such as biosensi
Externí odkaz:
https://doaj.org/article/973da5b2b1164c5fae8f320e4c91d055
Autor:
Juan Carlos García-Soriano, Héctor de Lucio, Daniel Elvira-Blázquez, Mercedes Alcón-Calderón, Natalia Sanz del Olmo, Pedro A. Sánchez-Murcia, Paula Ortega, Francisco Javier de la Mata, Antonio Jiménez-Ruiz
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
Species of Leishmania and Trypanosoma genera are the causative agents of relevant parasitic diseases. Survival inside their hosts requires the existence of a potent antioxidant enzymatic machinery. Four iron superoxide dismutases have been described
Externí odkaz:
https://doaj.org/article/8b837ee27de94e09b9a3c10679f946f3
Autor:
Noelia Hernández-Ortiz, Pedro A. Sánchez-Murcia, Celia Gil-Campillo, Mirian Domenech, Daniel Lucena-Agell, Rafael Hortigüela, Sonsoles Velázquez, María José Camarasa, Noemí Bustamante, Sonia de Castro, Margarita Menéndez
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Cationic ultrashort lipopeptides (USLPs) are promising antimicrobial candidates to combat multidrug-resistant bacteria. Using DICAMs, a newly synthesized family of tripeptides with net charges from −2 to +1 and a fatty amine conjugated to the C-ter
Externí odkaz:
https://doaj.org/article/a70e508a6e444b3684cb75e82eb032ee
Autor:
Johannes Bitter, Martin Pfeiffer, Annika J. E. Borg, Kirill Kuhlmann, Tea Pavkov-Keller, Pedro A. Sánchez-Murcia, Bernd Nidetzky
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Biological degradation of natural product glycosides involves, alongside hydrolysis, β-elimination for glycosidic bond cleavage. Here, we discover an O-glycoside β-eliminase (OGE) from Agrobacterium tumefaciens that converts the C3-oxidize
Externí odkaz:
https://doaj.org/article/716101903c9c4f90bd2ea47a7ac4134f
Autor:
Emil Spreitzer, T. Reid Alderson, Benjamin Bourgeois, Loretta Eggenreich, Hermann Habacher, Greta Bramerdorfer, Iva Pritišanac, Pedro A. Sánchez-Murcia, Tobias Madl
Publikováno v:
Current Research in Structural Biology, Vol 4, Iss , Pp 118-133 (2022)
Transcription factors play key roles in orchestrating a plethora of cellular mechanisms and controlling cellular homeostasis. Transcription factors share distinct DNA binding domains, which allows to group them into protein families. Among them, the
Externí odkaz:
https://doaj.org/article/7f409bd87d6e4290a919dff475fc1900
Autor:
Chiara Trigili, Isabel Barasoain, Pedro A. Sánchez-Murcia, Katja Bargsten, Mariano Redondo-Horcajo, Aurora Nogales, Nicola M. Gardner, Arndt Meyer, Guy J. Naylor, Elena Gómez-Rubio, Federico Gago, Michel O. Steinmetz, Ian Paterson, Andrea E. Prota, J. Fernando Díaz
Publikováno v:
ACS Omega, Vol 1, Iss 6, Pp 1192-1204 (2016)
Externí odkaz:
https://doaj.org/article/7a9614ea15bd4eb2ab39764aba08c975
Publikováno v:
Biomolecules, Vol 11, Iss 1, p 120 (2021)
Herein we report the first proof for the application of type II 2′-deoxyribosyltransferase from Lactobacillus delbrueckii (LdNDT) in suicide gene therapy for cancer treatment. To this end, we first confirm the hydrolytic ability of LdNDT over the n
Externí odkaz:
https://doaj.org/article/1c63233fbb5d40ebad3071c5ac28aeb3
Autor:
Javier Rocha-Martin, Pedro A. Sánchez-Murcia, Fernando López-Gallego, Aurelio Hidalgo, José Berenguer, José M. Guisan
Publikováno v:
Microorganisms, Vol 7, Iss 11, p 515 (2019)
The Thermus thermophilus strain HB27 NADH-oxidase (Tt27-NOX) catalyzes the oxidation of nicotinamide adenine dinucleotide (NAD(P)H) by reducing molecular oxygen to hydrogen peroxide in a two-electron transfer mechanism. Surprisingly, Tt27-NOX showed
Externí odkaz:
https://doaj.org/article/4acb424d355d4dfa82c3da5d470f3b16
Autor:
Daniel Platero-Rochart, Tatyana Krivobokova, Michael Gastegger, Gilbert Reibnegger, Pedro Alejandro Sánchez-Murcia
The prediction of enzyme activity in a general extend is maybe one of the main challenges nowadays in catalysis. Computer-assisted methods have been proven to be able to simulate the reaction mechanism at the atomic level of detail. However, these me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdd4f533d758ffb255e3da143e872337
https://doi.org/10.26434/chemrxiv-2023-v0rj6
https://doi.org/10.26434/chemrxiv-2023-v0rj6
Autor:
Héctor de Lucio, Alejandro Revuelto, Alejandra A. Carriles, Sonia de Castro, Sonia García-González, Juan Carlos García-Soriano, Mercedes Alcón-Calderón, Pedro A. Sánchez-Murcia, Juan A. Hermoso, Federico Gago, María-José Camarasa, Antonio Jiménez-Ruiz, Sonsoles Velázquez
Publikováno v:
European journal of medicinal chemistry. 244
N-methylation of the triazole moiety present in our recently described triazole-phenyl-thiazole dimerization disruptors of Leishmania infantum trypanothione disulfide reductase (LiTryR) led to a new class of potent in- hibitors that target different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef646e59d43fd7ad91c8810435c36267
https://pubmed.ncbi.nlm.nih.gov/36332553
https://pubmed.ncbi.nlm.nih.gov/36332553