Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Pedro A San-Segundo"'
Autor:
Esther Herruzo, Estefanía Sánchez-Díaz, Sara González-Arranz, Beatriz Santos, Jesús A Carballo, Pedro A San-Segundo
Publikováno v:
PLoS Genetics, Vol 19, Iss 11, p e1011026 (2023)
The meiotic recombination checkpoint reinforces the order of events during meiotic prophase I, ensuring the accurate distribution of chromosomes to the gametes. The AAA+ ATPase Pch2 remodels the Hop1 axial protein enabling adequate levels of Hop1-T31
Externí odkaz:
https://doaj.org/article/9300ae190f1341c2bbea7e33019e69f9
Autor:
Esther Herruzo, Ana Lago-Maciel, Sara Baztán, Beatriz Santos, Jesús A Carballo, Pedro A San-Segundo
Publikováno v:
PLoS Genetics, Vol 17, Iss 7, p e1009560 (2021)
During meiosis, defects in critical events trigger checkpoint activation and restrict cell cycle progression. The budding yeast Pch2 AAA+ ATPase orchestrates the checkpoint response launched by synapsis deficiency; deletion of PCH2 or mutation of the
Externí odkaz:
https://doaj.org/article/bac9f12a83d149aeafe0e4e147a43d54
Autor:
Laura I Lascarez-Lagunas, Esther Herruzo, Alla Grishok, Pedro A San-Segundo, Mónica P Colaiácovo
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009171 (2020)
Epigenetic modifiers are emerging as important regulators of the genome. However, how they regulate specific processes during meiosis is not well understood. Methylation of H3K79 by the histone methyltransferase Dot1 has been shown to be involved in
Externí odkaz:
https://doaj.org/article/1d2bc3070aa04de7829edcf062d6d680
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003262 (2013)
During meiosis, accurate chromosome segregation relies on the proper interaction between homologous chromosomes, including synapsis and recombination. The meiotic recombination checkpoint is a quality control mechanism that monitors those crucial eve
Externí odkaz:
https://doaj.org/article/794e34e04ff34b8ba036531577dc9d5a
Publikováno v:
PLoS Genetics, Vol 8, Iss 7, p e1002826 (2012)
Regulation of PCNA ubiquitylation plays a key role in the tolerance to DNA damage in eukaryotes. Although the evolutionary conserved mechanism of PCNA ubiquitylation is well understood, the deubiquitylation of ubPCNA remains poorly characterized. Her
Externí odkaz:
https://doaj.org/article/c3bba1be09b94deabe0721797b94d9ec
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20948 (2011)
Meiosis, a specialized cell division with a single cycle of DNA replication round and two consecutive rounds of nuclear segregation, allows for the exchange of genetic material between parental chromosomes and the formation of haploid gametes. The st
Externí odkaz:
https://doaj.org/article/3f38cecdbae24c8bb100d25c1a9ebfc6
Autor:
Ramya Ravindranathan, Kavya Raveendran, Frantzeskos Papanikos, Pedro A San-Segundo, Attila Tóth
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Generation of haploid gametes depends on a modified version of homologous recombination in meiosis. Meiotic recombination is initiated by single-stranded DNA (ssDNA) ends originating from programmed DNA double-stranded breaks (DSBs) that are generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfcb81ffc187acca5cce2dcc1fc6b575
https://doi.org/10.1093/nar/gkac355
https://doi.org/10.1093/nar/gkac355
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cells
Volume 10
Issue 10
Cells, Vol 10, Iss 2561, p 2561 (2021)
instname
Cells
Volume 10
Issue 10
Cells, Vol 10, Iss 2561, p 2561 (2021)
During meiosis, the budding yeast polo-like kinase Cdc5 is a crucial driver of the prophase I to meiosis I (G2/M) transition. The meiotic recombination checkpoint restrains cell cycle progression in response to defective recombination to ensure prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0cfcfe01df66a03367f97e196881cde
http://hdl.handle.net/10261/261150
http://hdl.handle.net/10261/261150
Autor:
Jesús A. Carballo, Ana Lago-Maciel, Esther Herruzo, Sara Baztán, Pedro A. San-Segundo, Beatriz Santos
Publikováno v:
PLoS Genetics, Vol 17, Iss 7, p e1009560 (2021)
PLoS Genetics
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Genetics
Digital.CSIC. Repositorio Institucional del CSIC
instname
During meiosis, defects in critical events trigger checkpoint activation and restrict cell cycle progression. The budding yeast Pch2 AAA+ ATPase orchestrates the checkpoint response launched by synapsis deficiency; deletion of PCH2 or mutation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a57cbf4825de1263f30ba61279b23cb
https://doaj.org/article/bac9f12a83d149aeafe0e4e147a43d54
https://doaj.org/article/bac9f12a83d149aeafe0e4e147a43d54
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
The meiotic recombination checkpoint blocks meiotic cell cycle progression in response to synapsis and/or recombination defects to prevent aberrant chromosome segregation. The evolutionarily conserved budding yeast Pch2TRIP13AAA+ATPase participates i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f6879a7ba3143995925455cb902d7c
https://doi.org/10.1007/s00412-019-00696-7
https://doi.org/10.1007/s00412-019-00696-7